Female Genital Pathology II Flashcards

1
Q

leukorrhea curd like in vagina
pruritis
erythema

A

candida albicans

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2
Q

flagella protozoan

A

trichomonas vaginalis

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3
Q

strawberry cervix

A

trichomonas vaginalis

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4
Q

trichomonas vaginalis

A

STD - 4 days to 4 weeks

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5
Q

yellow frothy discharge, pruritis, dysuria, dyspareunia, red vaginal/cervical mucosa

A

trichomonas vaginalis

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6
Q

clue cells

A

gardnerella vaginalis

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7
Q

fishy vagina smell

A

gardnerella vaginalis

gray-green discharge

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8
Q

culture of gardnerella

A

chocolate agar

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9
Q

vaginitis

A

candida albicans
trichomonas vaginalis
mycoplasma
gardnerella

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10
Q

diagnosis of candida

A

KOH prep

pap smear

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11
Q

KOH yeast pseudohyphae

A

candida

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12
Q

flagellated protozoa on wet mount

A

trichomoniasis

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13
Q

vaginal atrophy

A

atrophic vaginalis

tx - topical estrogen

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14
Q

gram negative, intracellular, diplococci

A

gonococcus

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15
Q

skin lesion with umbilication

-can be itchy

A

molluscum contagiosum
-central pit - not blister

adults sex transmission
kids share towels

pox virus - type 2 is STD

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16
Q

PID organisms

A

neisseria gonorrhea
chlamydia

most common

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17
Q

PID

A

infection between uterine corpus

most infections - polymicrobial

typically due to endometrial infections

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18
Q

cervical motion tenderness

A

PID

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19
Q

complication of PID

A

rupture of tuboovarian abscess
infertility - scarring of tubes
ectopic pregnancy
intestinal obstruction

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20
Q

sex

A

can introduce organisms to PID

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21
Q

all patients diagnosed with acute PID

A

should be tested for HIV infection

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22
Q

salpingitis

A

inflammation of fallopian tubes

23
Q

acute salpingitis

A

neutrophils

24
Q

chronic salpingitis

A

plasma cells

25
Q

skene ducts

A

paraurethal ducts

26
Q

squamous atrophy

A

lichen sclerosis et atrophicus

27
Q

squamous hyperplasia - with itching and scratching

A

lichen simplex chronicus

28
Q

condyloma acuminatum

A

HPV

29
Q

infibulation

A

sew labia to cover lumen of vagina

30
Q

bartholin gland cyst

A

4 and 8 oclock of vagina

obstruction of duct
-common all ages

can become infected > abscess

31
Q

tx bartholin gland cyst

A

incise and drain - high recurrence

word catheter - induces fistula formation
marsupialization - purse - cyst sewn inside out

32
Q

planar, pruritic, purple, papular

A

4 Ps of lichen planus

inflammatory dermatoses of the vulva

33
Q

lichen planus

A

squamous epithelium normal thickness

-chronic inflammation at derm/epiderm junction

34
Q

increased risk of cancer development of vulva

A

lichen sclerosus

35
Q

lichen sclerosus et atrophicus

A

elderly and post-menopausal women

atrophic changes

white/tense skin** - parchment like areas

tx - corticosteroids

36
Q

hyalinzation in vulva lesion

A

lichen sclerosis - collagen

37
Q

lichen simplex chronicus

A

squamous hyperplasia

pink lesion**

layer of keratin with thick epidermis
NO atypia

38
Q

chronic scratching

A

lichen simplex chronicus

39
Q

veneral warts

A

condyloma acuminatum

HPV 6 and 11 - low risk - 90%

high risk 10% - can go to VIN 2-3 and carcinoma

see koilocytosis

40
Q

high risk HPV

A

16, 18, 33

41
Q

tx of veneral warts

A

cryo
chemical
laser
excise

frequently regress

42
Q

biopsy of condyloma acuminatum

A

hyperkeratosis

43
Q

bowenoid papulosis

A

condylomata

44
Q

nuclear enlargement

A

high grade HPV

viral DNA incorporated into host

45
Q

koilocytosis

A

nuclei in a clear space

raisinoid nuclei

low grade HPV infection

46
Q

VIN

A

vulvar intraepithelial neoplasm
-pre-malignant

progression from dysplasia to invasive SCC

47
Q

VIN 1

A

low risk HPV 6, 11
mild dysplasia
see condyloma acuminatum

48
Q

VIN 2

A

moderate dysplasia

HPV 16,18

49
Q

VIN 3

A

severe dysplasia/CIS
HPV 16,18 - high risk

warty and basaloid

50
Q

bowenoid papulosis

A

multi discrete warty papules that coalesce into plaques

-reflects early HPV infection and may spontaneously resolve

51
Q

bowen disease

A

VIN 3 - CIS

-requires surgery

52
Q

risk of invasive SCC

A

age, extent of vulvar growth, smoking, immunocompromised, LS and A

53
Q

height of nuclear enlargement and VIN

A

full - high grade - VIN 3
half - moderate - VIN 2
low - low grade - VIN 1

54
Q

tx of VIN 1 and 2

A

conservative removal

-goal is negative margins