Female Genital Pathology I Flashcards
metrorrhagia
abnormal interval periods - MMR
menorrhagia
heavy bleeding
infertility
with PID and PCOD
mass effects
leiomyoma
ovarian neoplasms
red plaques of vulva
dermatitides
extramammary paget
ovary embryo
mesoderm germ cells
fallopian tube embryo
paired mullerian ducts
-aka paramesonephric
fuse to form fallopian tubes, uterus, upper vagina
fusion of mullerian ducts
at urogenital sinus
forms uterus
wolffian ducts
aka mesonephric
regress - they are male structure
rests may remain
all epithelial surfaces
lined with mesothelial (coelemic) origin
gartner duct cyst
remnant of wolffian duct
sexual abuse
need trauma and sperm
NOT hymen alone
also - culture for gonorrhea, herpes, etc.
ovarian serosa
invaginates into coelomic cavity - becomes covered with this during embryogenesis
epithelial inclusion cysts
serosa invaginates into ovary
didelphys
two cavities of uterus and double vagina
bicornuate
two uterus - failure of fusion of mullerian ducts
difficulty urinating
imperforate hymen
fills uterus with blood
spontaneous abortions
2nd and 3rd trimesters
occur with congenital anomalies of uterus and vagina
positions of uterus
anteverted
retroverted
anteflexed
retroflexed
covering of vagina and cervix
squamous mucosa
mucosa in endocervical canal
glandular
maintains position of uterus
round ligament
clue cells
gardnerella vaginalis
donovan body
klebsiella granulomatous
granuloma inguinale
spirochete
syphilis
trepnema pallidum
PID
chlamydia trachomatis
koilocyte change
HPV
multinucleated giant cell with intracellular inclusion
herpes
tzanck test
bulbous intranuclear inclusion body
CMV
molluscum bodies
molluscum contagiosum
trichomonad
trichomonas vaginalis
sulphur granules
actinomyces israelii
also causes PID
necrotizing granulomas
mycobacterium tuberculosis
candida
candida albicans
vaginal cuff
surrounding cervix
goal of pap smear
get both squamous AND glandular cells
location of herpes infection
vulva, vagina, cervix
location of molluscum infection
vulva
location of HPV infection
vulva, vagina, cervix
location of chlamydia trachomatis
cervix, corpus, adnexa
location of neisseria gonorrhea
vulva, vagina, cervix, corpus, adnexa
location of candida
vulva, vagina, cervix
genital herpes subtype
HHV-2
latency in neurons
herpes
DNA virus - PCR test on sample - IgG serology
phases of herpes
ulcer - active
latent - inactive
pain, dysuria, vesicles that erupt
- lasts 1-3 weeks
- systemic symptoms
- recurrence
herpes infection
vesicles - with neutrophils
tx of herpes
suppression and some symptomatic tx.
herpes complication
transmission to neonate at birth
this is most significant one
tzanck test
herpes
-of vesicle fluid - smear onto glass side
is diagnostic
multinuclear giant cell with ground glass intranuclear inclusions
herpesvirus
neonatal herpes
50% born to asymptomatic mothers
skin, eyes, mouth - 70% progress
-to CNS or disseminated
CNS - 50% mortality
disseminated - 85% mortality
tx for neonatal herpes
C section - if maternal infection present