Feline Panleukopenia & FIP (Exam 2) Flashcards
___________ mutates to form Feline Infectious Peritonitis.
feline coronavirus
FIP infects ________, causing “leaky” vessels and vasculitis.
macrophages
____________ inflammation occurs with FIP.
pyogranulomatous
What are the 2 forms of FIP?
- Wet Form (Effusive)
- Dry Form (Non-Effusive)
The Wet Form of FIP causes fluid to leak into what two locations?
peritoneum
pericardium
What primary lesion is seen in Dry Form FIP?
anterior uveitis
FIP is a ________ of Feline Coronavirus.
biotype
Feline Coronavirus which infects enterocytes and macrophages is called:
Transmissible Gastroenteritis Virus
(T/F) The vaccine for Feline Coronavirus or FIP is recommended but is not a core vaccine.
False - NOT recommended & noncore
What are two ways to definitively diagnosis FIP?
- immunocytochemistry
- visualize macrophages in fluid
(T/F) FIP infects lymphocytes which leads to leukopenia.
False!
FIP vaccination is only useful if the cat is _________.
seronegative
Why is FIP vaccination generally not effective?
covers serotype 2 (different than most common one that causes disease - Type 1)
Feline Panleukopenia is a (small/large) (enveloped/nonenveloped) (ss/ds) (RNA/DNA) virus.
small nonenveloped ssDNA virus
What is the significance of Feline Panleukopenia being a ssDNA virus?
forms intranuclear inclusion bodies
What 3 locations does disease occur in cats infected by Feline Panleukopenia?
- bone marrow
- lymphoid tissue
- enterocytes
Feline Panleukopenia is associated with what condition, especially in neonates up to 2 weeks in age?
cerebellar hypoplasia
All felids can be infected with Feline Panleukopenia. Recently ________ kittens are at greater risk of infection.
weaned
(T/F) Dogs are at risk for Feline Panleukopenia.
False
Feline Panleukopenia virus replicates in __________ tissues.
mitotically active
_____% of circulating WBCs decrease with Feline Panleukopenia infection.
90%
List the 4 possible clinical syndromes that can occur with Feline Panleukopenia infection and what age groups are associated.
- Subclinical (healthy adults)
- Enteritis + Bone Marrow/Lymphocyte Infection (2-6 month kittens)
- Perinatal infection (neonates)
- In-utero infection (fetus)
What is the primary mode of transmission for Feline Panleukopenia?
fecal-oral (can be vertical transmission)
Incubation period of Feline Panleukopenia.
5 days
(T/F) Feline Panleukopenia is a core vaccine.
True
