Feline Panleukopenia & FIP (Exam 2)

Question 1

___________ mutates to form Feline Infectious Peritonitis.

Answer 1

feline coronavirus

Question 2

FIP infects ________, causing “leaky” vessels and vasculitis.

Answer 2

macrophages

Question 3

____________ inflammation occurs with FIP.

Answer 3

pyogranulomatous

Question 4

What are the 2 forms of FIP?

Answer 4

1. Wet Form (Effusive)
2. Dry Form (Non-Effusive)

Question 5

The Wet Form of FIP causes fluid to leak into what two locations?

Answer 5

peritoneum
pericardium

Question 6

What primary lesion is seen in Dry Form FIP?

Answer 6

anterior uveitis

Question 7

FIP is a ________ of Feline Coronavirus.

Answer 7

biotype

Question 8

Feline Coronavirus which infects enterocytes and macrophages is called:

Answer 8

Transmissible Gastroenteritis Virus

Question 9

(T/F) The vaccine for Feline Coronavirus or FIP is recommended but is not a core vaccine.

Answer 9

False - NOT recommended & noncore

Question 10

What are two ways to definitively diagnosis FIP?

Answer 10

1. immunocytochemistry
2. visualize macrophages in fluid

Question 11

(T/F) FIP infects lymphocytes which leads to leukopenia.

Answer 11

False!

Question 12

FIP vaccination is only useful if the cat is _________.

Answer 12

seronegative

Question 13

Why is FIP vaccination generally not effective?

Answer 13

covers serotype 2 (different than most common one that causes disease - Type 1)

Question 14

Feline Panleukopenia is a (small/large) (enveloped/nonenveloped) (ss/ds) (RNA/DNA) virus.

Answer 14

small nonenveloped ssDNA virus

Question 15

What is the significance of Feline Panleukopenia being a ssDNA virus?

Answer 15

forms intranuclear inclusion bodies

Question 16

What 3 locations does disease occur in cats infected by Feline Panleukopenia?

Answer 16

1. bone marrow
2. lymphoid tissue
3. enterocytes

Question 17

Feline Panleukopenia is associated with what condition, especially in neonates up to 2 weeks in age?

Answer 17

cerebellar hypoplasia

Question 18

All felids can be infected with Feline Panleukopenia. Recently ________ kittens are at greater risk of infection.

Answer 18

weaned

Question 19

(T/F) Dogs are at risk for Feline Panleukopenia.

Answer 19

False

Question 20

Feline Panleukopenia virus replicates in __________ tissues.

Answer 20

mitotically active

Question 21

_____% of circulating WBCs decrease with Feline Panleukopenia infection.

Answer 21

90%

Question 22

List the 4 possible clinical syndromes that can occur with Feline Panleukopenia infection and what age groups are associated.

Answer 22

1. Subclinical (healthy adults)
2. Enteritis + Bone Marrow/Lymphocyte Infection (2-6 month kittens)
3. Perinatal infection (neonates)
4. In-utero infection (fetus)

Question 23

What is the primary mode of transmission for Feline Panleukopenia?

Answer 23

fecal-oral (can be vertical transmission)

Question 24

Incubation period of Feline Panleukopenia.

Answer 24

5 days

Question 25

(T/F) Feline Panleukopenia is a core vaccine.

Answer 25

True