Canine Parvovirus (Exam 2) Flashcards
Canine Parvovirus is a (small/large), (enveloped/non-enveloped), (ssDNA/ssRNA/dsDNA/dsRNA) virus.
small non-enveloped ssDNA
(T/F) Canine Parvovirus is zoonotic.
False
(T/F) Canine Parvovirus-1 is the concerning, life-threatening strain of parvovirus.
False (2!!!)
Canine Parvovirus-2 causes what two major conditions?
enteritis
myocarditis
Canine Parvovirus-2 is a result of a mutation of _____________ virus.
Feline Panleukopenia
(T/F) Dogs and wild animals such as foxes, coyotes, and wolves can be affected by Canine Parvovirus-2, but is it most severe in young puppies.
True
(T/F) Canine Parvovirus-2 can infect cats.
True - can shed virus and similar to panleukopenia
(T/F) Cats vaccinated for Feline Panleukopenia Virus receive cross-protection against CPV-2.
True
What is the primary sign of Canine Parvovirus?
diarrhea
Canine Parvovirus causes (diffuse/segmented) infection of the intestines.
segmented
Which variant of CPV is a common isolate which causes enteritis to dogs in the US?
CPV-2b
(T/F) Vaccines for CPV are effective against all strains and the tests detect all known variants.
True
How is Canine Parvovirus transmitted?
feces or fomites
Canine Parvovirus can survive in the environment for up to ____ months and is resistant to __________.
5
disinfectants
What phase of the cell cycle does Canine Parvovirus require for replication in the host cell nucleus?
S phase
Canine Parvovirus first infects lymphoid tissue of the oropharynx and replicates in the host nucleus. Then _________ occurs 1-5 days after infection.
primary viremia
After primary viremia, Canine Parvovirus infects ________ epithelium and eventually, _____ necrosis leading to diarrhea.
crypt
What is the incubation period of CPV?
7-14 days
(T/F) CPV is not actively shed until the onset of diarrhea.
False - before onset
Myocarditis develops with CPV without sufficient ________ around 3 weeks of age.
maternal antibody
_________ is a diagnostic method used for CPV in hospital, however false negatives are possible and the modified-live vaccine causes a false positive 5-12 days post-vaccination.
ELISA
For serology, ______ levels are not very useful for CPV diagnosis as they go up after viral replication stops.
IgG
What disinfectant is used for CPV?
diluted household bleach (1:30) for 10 min
Puppies with CPV should not go to any dog parks, kennels, or other locations with high dog volume until __________.
fully vaccinated
What is the most common cause of vaccination failure in puppies?
blocking by maternal antibodies
Canine Coronavirus is a(n) (enveloped/nonenveloped) (RNA/DNA) virus.
enveloped RNA
Canine Coronavirus is (resistant/sensitive) to change in temperature and (resistant/sensitive) to disinfectants.
resistant
sensitive
Canine Coronavirus is a (core/noncore) vaccine.
non-core (may be recommended in kennels)
CPV testing in a diagnostic lab is more accurate for diagnosis. Which two tests are used?
histopath
PCR
ELISA is (more/less) sensitive than PCR for CPV.
less (send it out if negative!)
In dogs 6 weeks and older, the predominant clinical signs of CPV are:
enteritis + leukopenia
Canine Coronavirus replicates in what cell type?
enterocytes
