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Virology > Canine Distemper (Exam 2) > Flashcards

Canine Distemper (Exam 2) Flashcards

1
Q

(T/F) Canine Distemper is a systemic disease affecting multiple organs.

A

True

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2
Q

Where does most disease of Canine Distemper occur?

A

shelters/rescues (lack of vax history)

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3
Q

Canine Distemper often infects ________ which leads to companion animals becoming infected.

A

raccoons

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4
Q

_______ are the principal reservoir host for Canine Distemper.

A

dogs

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5
Q

All cats can become infected and develop clinical disease from CDV.

A

False - wild cats only

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6
Q

(T/F) Domestic cats cannot become infected with Canine Distemper.

A

False - infected w/o clinical disease

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7
Q

Dogs are the greatest risk for Canine Distemper are what age range?

A

3-6 months

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8
Q

How is Canine Distemper transmitted?

A

aerosols (respiratory)

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9
Q

Dogs infected with Canine Distemper can begin shedding by day ____ post-infection which can persistent for _____ to ____ days.

A

day 7
60-90 days

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10
Q

Canine Distemper is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.

A

enveloped RNA virus

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11
Q

(T/F) Canine Distemper is highly resistant to heat and disinfectants.

A

False - easily destroyed

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12
Q

(T/F) Canine Distemper is NOT believed to be zoonotic.

A

True

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13
Q

Canine Distemper is spread through aerosols and infects __________ within 24 hours which spreads to the tonsils and bronchial lymph nodes.

A

macrophages

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14
Q

Within ___ to ___ days after infection, primary viremia and multiplication of CDV occur in multiple organs such as spleen, thymus, stomach, intestines, and liver.

A

4-6 days

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15
Q

After primary viremia and multiplication, fever and _________ occur during CDV infection.

A

lymphopenia

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16
Q

After fever and lymphopenia, _________ occurs from day 8-10 in CDV infection.

A

secondary viremia

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17
Q

During secondary viremia of CDV, what two tissue types become infected with the virus?

A

epithelium
CNS

18
Q

By day 14 of CDV infection, _____ antibody and _________ immunity block further spread of the virus.

A

IgG
cell-mediated

19
Q

(T/F) Canine Distemper can remain subclinical and not cause disease in some animals.

A

True

20
Q

In mild cases of Canine Distemper, its clinical signs are often confused with:

A

kennel cough

21
Q

What rare condition occurs when skin becomes infected by Canine Distemper?

A

hyperkeratosis

22
Q

In young and immunosuppressed dogs, CDV causes cytolytic injury to neurons, leading to a demyelinating disease and neural necrosis. This is called:

A

Acute Canine Distemper Virus Encephalitis

23
Q

(T/F) Because CDV infected many tissues in the body, it is fairly easy to determine infection when testing infected tissue.

A

False - needs to be sampled at the right time or false negative

24
Q

Serum _____ antibody tests are useful in diagnosis of Canine Distemper Virus.

A

IgM

25
Q

(T/F) It is difficult to differentiate between vaccination and an active infection of Canine Distemper Virus with a serum antibody test.

A

True

26
Q

Canine Distemper is a (core/noncore) vaccine and currently protects against all known strains.

A

core

27
Q

When vaccinated wildlife, ________ vaccine type should be used.

A

recombinant

28
Q

Which animal is a canarypox-vectored recombinant vaccine used for CDV?

A

ferrets

29
Q

Canine Herpes Virus 1 is a(n) _________-herpesvirus.

A

alpha

30
Q

Canine Herpes Virus 1 is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.

A

enveloped DNA virus

31
Q

Many dogs are __________ for Canine Herpes Virus 1 so clinical disease is rare.

A

seropositive

32
Q

(T/F) Canine Herpes Virus 1 is not stable in the environment and easily destroyed by heat and disinfectants.

A

True

33
Q

Canine Herpes Virus 1 is a disease which infects which two systems?

A

respiratory system
genitals

34
Q

Canine Herpes Virus 1 can remain ________ in dogs, shed intermittently, and not detected by blood samples or other testing.

A

latent

35
Q

What 3 ways is Canine Herpes Virus 1 transmitted?

A

oronasal
genital
maternal transmission

36
Q

__________ is not a good sample for PCR testing for CHV-1 as latent infections are not detected.

A

blood

37
Q

CHV-1 infection causes a generalized viremia which is often fatal, followed by ________.

A

hypothermia

38
Q

Grossly, CHV-1 causes _________ and ________ of multiple tissues such as kidney, liver, lung, adrenal glands, heart, intestines, and spleen.

A

necrosis + hemorrhage

39
Q

(T/F) There is no CHV-1 vaccine available in the US.

A

True

40
Q
A

Virology (13 decks)

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