Canine Distemper (Exam 2) Flashcards
(T/F) Canine Distemper is a systemic disease affecting multiple organs.
True
Where does most disease of Canine Distemper occur?
shelters/rescues (lack of vax history)
Canine Distemper often infects ________ which leads to companion animals becoming infected.
raccoons
_______ are the principal reservoir host for Canine Distemper.
dogs
All cats can become infected and develop clinical disease from CDV.
False - wild cats only
(T/F) Domestic cats cannot become infected with Canine Distemper.
False - infected w/o clinical disease
Dogs are the greatest risk for Canine Distemper are what age range?
3-6 months
How is Canine Distemper transmitted?
aerosols (respiratory)
Dogs infected with Canine Distemper can begin shedding by day ____ post-infection which can persistent for _____ to ____ days.
day 7
60-90 days
Canine Distemper is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.
enveloped RNA virus
(T/F) Canine Distemper is highly resistant to heat and disinfectants.
False - easily destroyed
(T/F) Canine Distemper is NOT believed to be zoonotic.
True
Canine Distemper is spread through aerosols and infects __________ within 24 hours which spreads to the tonsils and bronchial lymph nodes.
macrophages
Within ___ to ___ days after infection, primary viremia and multiplication of CDV occur in multiple organs such as spleen, thymus, stomach, intestines, and liver.
4-6 days
After primary viremia and multiplication, fever and _________ occur during CDV infection.
lymphopenia
After fever and lymphopenia, _________ occurs from day 8-10 in CDV infection.
secondary viremia
During secondary viremia of CDV, what two tissue types become infected with the virus?
epithelium
CNS
By day 14 of CDV infection, _____ antibody and _________ immunity block further spread of the virus.
IgG
cell-mediated
(T/F) Canine Distemper can remain subclinical and not cause disease in some animals.
True
In mild cases of Canine Distemper, its clinical signs are often confused with:
kennel cough
What rare condition occurs when skin becomes infected by Canine Distemper?
hyperkeratosis
In young and immunosuppressed dogs, CDV causes cytolytic injury to neurons, leading to a demyelinating disease and neural necrosis. This is called:
Acute Canine Distemper Virus Encephalitis
(T/F) Because CDV infected many tissues in the body, it is fairly easy to determine infection when testing infected tissue.
False - needs to be sampled at the right time or false negative
Serum _____ antibody tests are useful in diagnosis of Canine Distemper Virus.
IgM
(T/F) It is difficult to differentiate between vaccination and an active infection of Canine Distemper Virus with a serum antibody test.
True
Canine Distemper is a (core/noncore) vaccine and currently protects against all known strains.
core
When vaccinated wildlife, ________ vaccine type should be used.
recombinant
Which animal is a canarypox-vectored recombinant vaccine used for CDV?
ferrets
Canine Herpes Virus 1 is a(n) _________-herpesvirus.
alpha
Canine Herpes Virus 1 is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.
enveloped DNA virus
Many dogs are __________ for Canine Herpes Virus 1 so clinical disease is rare.
seropositive
(T/F) Canine Herpes Virus 1 is not stable in the environment and easily destroyed by heat and disinfectants.
True
Canine Herpes Virus 1 is a disease which infects which two systems?
respiratory system
genitals
Canine Herpes Virus 1 can remain ________ in dogs, shed intermittently, and not detected by blood samples or other testing.
latent
What 3 ways is Canine Herpes Virus 1 transmitted?
oronasal
genital
maternal transmission
__________ is not a good sample for PCR testing for CHV-1 as latent infections are not detected.
blood
CHV-1 infection causes a generalized viremia which is often fatal, followed by ________.
hypothermia
Grossly, CHV-1 causes _________ and ________ of multiple tissues such as kidney, liver, lung, adrenal glands, heart, intestines, and spleen.
necrosis + hemorrhage
(T/F) There is no CHV-1 vaccine available in the US.
True
