Feline Flashcards
Acetaminophin toxicity
cats are unable to process acetaminophen because of deficiencies int he liver’s ability to glucuronidate the drug into a form that can be excreted by the body. When the liver’s enzyme pathways for glucuronidation is saturated, the drug is broken down into a toxic metabolite called NAPQI that damages hemoglobin and red blood cells and liver cells. This can lead to fatal methemoglobinemia followed by acute liver damage (Heinz bodies and glossy brown color of the blood). Although liver failure and life-threatening methemoglobinemia are the two primary processes that occur, some cats may develop renal failure from nephrotoxicity. Renal failure occurs more infrequently, however.
Acute cholangiohepatitis
usually seen in younger cats (3-3.5 years) and is more common in males than in females. Likely to be depressed, dehydrated, and febrile. Neutrophilia with or without left shift. Mild increase in bilirubin and ALP common, with more severe elevations of ALT. Treatment includes antibiotics with aerobic and anaerobic coverage that are excreted unchanged in the bile (tetracyclines, ampicillin, amoxicillin, erythromycin, chloramphenicol, and metronidazole). Ursodeoxycholic acid is useful in all types of inflammatory liver disease because of its anti-inflammatory and anti-fibrotic properties on the liver. It also increases fluidity of biliary secretions. 50% survival.
Acute Glaucoma
Very painful condition characterized by epiphora, episcleral injection, corneal edema, and sometimes mydriasis.
Aelurostrongylus abstrusus
feline lungworm, treat with ivermectin and fenbendazole
Amylase
Hydrolyzes starches: Enzyme produced by the pancreas and also found in saliva that is responsible for digestion of starch or carbohydrates.
Amyloidosis familial disorder affects ____ breeds. Clinical signs are associated with ____ and ___ failure, while ____ may be secondary to glomerulotubular disease. Diagnosis is via biopsy and ____ stain but often not done due to the high risk of hemorrhage.
Abyssinian (kidney), Siamese and Oriental (liver) shorthair. Amyloid deposition occurs most frequently in the kidney and liver. Clinical signs in Abyssinian are typically those of chronic renal failure. Hypertension may be secondary to glomerulotubular disease. Biopsy and stain with congo red definitive but often not necessary due to high risk of hemorrhage. Manage symptoms and do not breed from these cats.
Anterior uveitis
Rubiosis iridis, aqueous flare, hyphema, hypopyon, keratic precipitates, and decreased intraocular pressure are all suggestive of anterior uveitis which an be caused by a number of infectious, immune-mediated, traumatic, and idiopathic causes.
Arginine deficiency
Arginine is an essential amino acid in cats used to make ornithine, which binds to ammonia that is formed from the catabolism of protein. Deficiency results in build up of ammonia and signs similar to hepatic encephalopathy
Black widow spider bite
Clinical presentation: found in basement recumbent and vocalizing, very rigid with muscle spasms
Toxin binds calcium channels, increasing membrane permeability and enhancing depolarization. Ascending motor paralysis and destruction of peripheral nerve endings occur. A single bit may be serious to adult humans and could kill a small animal. Clinical signs occur almost immediately with pain, due in part to the release of acetylcholine, which stimulates contraction of major muscle groups. There may be ascending motor paralysis, muscle spasms, muscle rigidity, and salivation. Death from respiratory or cardiovascular failure is possible.
Calicivirus
acute presentation of marked upper respiratory signs as well as oral ulcerations +/- conjunctival chemosis, and edematous lesions of the skin on the head and limbs. outbreaks of highly virulent and often lethal strains have been seen.
Capillaria aerophila
lungworm, parasite of the frontal sinus, trachea, bronchi, and rarely nasal cavity.
Cate bite abscess
Anaerobes most frequently isolated bacteria in cat bit abscesses. These include obligate anaerobes such as Fusobacterium spp., Bacteroides spp., and Clostridium spp. as well as facultative anaerobes such as Pasteurella spp. and Actinmyces spp. Treatment by establishing drainage, vet still choose to treat with antibiotics (Clindamycin or amoxicillin with clavulanate)
Chlamydophila felis is a ____ pathogen. The characteristic lesion is severe ____. The drug class of choice for treatment is ____
Chlamydophila felis is a respiratory pathogen. The characteristic lesion is severe chemosis. The drug class of choice is tetracyclines.
Cholangiohepatitis
Inflammation of the biliary system and liver parenchyma. Can be autoimmune in nature, or may be triggered by underlying infection or neoplasia. Concurrent disease often includes pancreatitis and inflammatory bowel disease.
Treatment: for non-suppurative cholangiohepatitis is prednisolone since it is most often immune in origin. Ursodiol is often used for its immunomodulatory, hepatoprotectant, and antifibrotic effects.It helps with the flow of bile through the liver. Other helpful therapies include S-adenosylmethionene (SAMe) and Vitamin E.
Chronic cholangiohepatitis
occurs in older cats (mean age 9 years)
Chronic kidney failure management
Restrict dietary protein (decreases formation of nitrogenous wastes and help to palliate hyperphosphatemia), phosphate binders (prevent absorption of phosphorus from the intestines), H2 blockers (decrease gastric acid secretion to help prevent vomiting and formation of gastric ulcers), Calcium channel blockers like amlodipine (palliate hypertension)
Cobalamin deficiency
causes inappetence, lethargy, and failure to thrive
Common congenital defect of white cats with blue eyes
deaf
Corneal dermoid
congenital
Cryptococcus neoformans
yeast-like fungus which has narrow based budding. Clinical signs: respiratory, central nervous system, eyes and skin are usually areas you will see affected. Most have nasal involvement characterized by facial swelling, distortion ‘roman nose’, chronic snuffling and discharge, and granulomatous masses seen coming out of the nostril.
Treat with Itraconazole
Diagnosis: serology is very useful, latex agglutination on serum, CFS, or urine. Visible yeasts surrounded by a large capsuleoccasionallyy seen.
Cryptosporidium
A coccidian that invades the small intestinal villi after ingestion of infected oocysts. It can be diagnosed with PRC. It is treated with clindamycin, azithromycin, or tylosin most commonly. It is usually an opportunist, so evaluation for underlying disease is appropriate.
Cuterebra
Fly that lays its eggs on soil or plants. The eggs stick to the animal’s fur when they come into contact. The eggs hatch and the larvae either penetrate the skin, are ingested when the animal grooms; or they enter the animal’s body through a natural opening, such as the nose. In most cases, the larvae migrate to areas just under the skin on the head, neck, or trunk of the animal. In dogs, cats, and ferrets, who are not the usually hosts of this parasite, the larvae may also migrate to the brain, eye, eyelids, or throat. As the larva grows under the skin, it produces a nodule or swelling.A small opening develops in the skin, through which is breathes. A small amount of drainage may occur around this breathing hole. The treatment is to incise the skin if needed to remove the larva. You have to make sure to remove the larva in whole and not crush it. If it is damaged or crushed, it can cause an anaphylactic reaction.
cytauxzoon felis is transmitted by _____, cats show clinical signs ____ after infection and these include a charateristic scleral _____, marked ____, icterus or pallor, an anemia associated ____ and thrombocytopenia. This organism lives in ____ as well as
Cytauxzoon felis is trasmitted by ticks, Cats usually show clinical signs 1-3 weeks after infection. Signs can include a characteristic scleral hemorrhage, marked pyrexia, icterus or pallor, an anemia-associated heart murmur and thrombocytopenia. This organism lives in the red blood cells as well as reticuloendothelial cells of the lungs, spleen, liver, lymph nodes. Cranial organomegaly can often be present. The bone marrow can be affected causing pancytopenias. Thrombocytopenia is likely related to the development of DIC. There is no effective therapy and prognosis is poor to grave.
Demodex cati
long slender mite which lives in the hair follicles
Diagnose on deep skin scrape
Treat with lime sulfur dip

