Fatty Acid Synthesis Flashcards

1
Q

Process by which saturated fatty acid Palmitate is formed

Excess carbohydrates are converted to fatty acids creating a store of energy able to be broken down for future energy

A

Fatty acid synthesis

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2
Q

Acetyl coa cannot be shuttled from mitochondria to

A

Cytoplasm to be converted to fatty acids

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3
Q

From the mitochondria, acetyl coa is converted into this subtrate that can be shuttled to the cytoplasm for production of fatty acids

A

Citrate

Citrate shuttle

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4
Q

Step 1

Citrate leaves mitochondria through citrate shuttle to the cytoplasm

Citrate -> Acetyl Coa by the enzyme

A

ATP Citrate lyase

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5
Q

Step 2

Acetyl CoA -> Malonyl Coa by enzyme

Rate limiting enzyme

Cofactor:

A

Acetyl Coa carboxylase

CO2

Fatty ACCid synthesis

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6
Q

Step 3

Malonyl Coa -> Palmitate by the enzyme

Cofactor:

A

Fatty acid Synthase

NADPH

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7
Q

Rate limiting enzyme of Fatty acid synthesis

A

Acetyl Coa Carboxylase

Acetyl Coa -> Malonyl Coa

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8
Q

Stimulates fatty acid synthesis

A

Insulin

Citrate

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9
Q

Inhibits fatty acid synthesis

A

Glucagon

Palmitoyl CoA

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