Electron Transport Chain Flashcards

1
Q

ETC is located on the

A

inner mitochondrial membrane

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2
Q

Main source of energy in the aerobic pathway of energy generation

A

Electron Transport Chain

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3
Q

Krebs Cycle
Beta oxidation
Occur in

A

Matrix of mitochondria

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4
Q

Movement of electrons generate energy utilized to pump H ions into the

A

Intermembrane space from the matrix of mitochondria

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5
Q

Higher concentration of ions is generated in the intermembrane space compared to the inner membrane space make it

A

Positively charged and generates electro-chemical gradient

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6
Q

This enzyme transports H ions into the matrix of mitochondria and uses energy generated from flow of H ions to phosphorylate ADP to ATP

A

ATP Synthase

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7
Q

Complex I

A

NADH Dehydrogenase Complex

NADH oxidoreductase

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8
Q

L shaped complex in the inner mitchondrial membrane

A

Complex I NADH Dehydrogenase

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9
Q

The vertical arm of complex I is located inside the

A

Inner mitochondrial membrane

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10
Q

The horizontal arm of complex I is located in the

A

Matrix of mitochondria

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11
Q

Complex I functions by

A

Removing hydrogen from reduced form of NAD

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12
Q

NADH Dehydrogenase also contains complexes:

A

FMN

Iron-sulfur compounds

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13
Q

Dehydrogenation is an example of this type of reduction

A

Oxido-reduction

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14
Q

Complex II

A

Succinate dehydrogenase Complex

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15
Q

Complex II removes H from succinyl and oxidizes it into

A

Fumarate

Krebs cycle

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16
Q

Complex II is also called a complex because it contains

A

Iron-sulfur clusters

Succinate dehydrogenase

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17
Q

Oxidation of succinate to fumarate produces a reducing equivalent of

A

FADH2 utilized to transport electron to Complex III

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18
Q

Complex III

A

Cytochrome reductase

Q-cytochrome C Oxidoreductase

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19
Q

Group of proteins with heme as complexes or prosthetic groups and iron cores where it can exist in an oxidized or reduced form

A

Cytochrome

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20
Q

Complex III contains 3 types of cytochromes:

A

Cytochrome b
Cytochrome C1
Cytochrome C

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21
Q

The cytochrome component of complex III that transfers it to Complex IV

A

Cytochrome C

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22
Q

Complex IV

A

Cytochrome C oxidase

23
Q

A heme and copper containing complex whose main job is to oxidize cytochrome C or receive electrons and use it for the reduction of oxygen to water

A

Cytochrome C oxidase

24
Q

ETC begins when NADH donates its first electron to the first complex and are received by the prosthetic groups

The electrons are then received by

This is a type of reaction called

A

FMN

Iron-sulfur Fe-S proteins

Redox

Ferrous-Ferric

25
Fe-S proteins donate electrons to
Co-enzyme Q
26
Ubiquinone freely permeable molecule inside the inner mitochondrial membrane
Coenzyme Q Redox
27
The first two redox reactions in complex I and complex II are used to generate energy to pump
4 H ions from matrix to inner membrane space
28
2 H ions from the matrix combine with Coenzyme q and gets converted to
Reduced form of ubiquinone
29
The second complex contains this enzyme which catalyzes the conversion of succinate to fumarate in Krebs (redox) causing generation of
Succinate dehydrogenase FADH2
30
FADH2 stays inside complex II and donates electrons to Fe-S. The electrons are then transferred to
Ubiquinone
31
Freely permeable molecule used to transfer electron to third complex
Ubiquinone
32
In complex III, the electrons are first received by
cytochrome C1
33
Cytochrome C1 transfers electrons to
Fe-S proteins donating electrons to cytochrome b
34
Cytochrome b transfers electrons to cytochrome C which is used to donate electrons to
Complex IV
35
Redox reactions inside complex III cause
pumping of 4 H ions to intermembrane space
36
Complex IV receives electrons from cytochrome C via
Copper ions (a type?) then donate to cytochrome A and transfers electrons to copper ions (b type)
37
Copper ions b type transfer electrons to
Cytochrome A3
38
Cytochrome A3 transfers electrons to final electron acceptor which is:
oxygen
39
Oxygen combines with 2 molecules of H and get reduced to become:
water
40
Redox reactions in complex IV cause pumping of
2 H ions to intermembrane space
41
All the pumping of H ions to intermembrane space cause
High concentration creating electro-chemical gradient used by ATP synthase to phosphorylate ATP from ADP
42
Glucose -> Pyruvate (Glycolysis) Net of ATP? Net of NADH? Total of?
2 ATPs | 2 NADH
43
Pyruvate -> Acetyl Coa Net NADH?
2 NADH
44
Krebs Cycle (1 by glucose) Net GTP? Net NADH? Net FADH2?
2 GTPS 6 NADH 2 FADH2
45
ETC Net NADH? Net FADH2?
``` 2 NADH (Glycolysis) = 5 ATP 2 NADH (Pyruvate -> Acetyl Coa) = 5 ATP 6 NADH (Krebs) = 15 ATP 2 FADH2 (Krebs) = 3 ATP ```
46
In the Electron Transport Chain, for every 4 H ions that flow through ATP synthase, how many ATP is generated?
1 ATP
47
1 NADH = | how many H ions?
10 H ions | Giving rise to 2.5 ATPs
48
1 NADH = ATPs?
2.5 ATPs
49
1 FADH2 = H?
6 H ions | Generating 1.5 ATPs
50
1 FADH2 = ATP?
1.5 ATP
51
Glucose -> Pyruvate Net ATP?
7 ATP
52
Pyruvate -> Acetyl Coa Net ATP?
5 ATP
53
Krebs Cycle Net ATP?
20 ATP
54
Glycolysis Pyruvate to Acetyl CoA Krebs ETC Total ATP yield:
32 ATPs