FATIMA

Question 1

causes pulmonary and hepatic toxicity with long-term use

Answer 1

nitrofurantoin

Question 2

which agents are used to reduce the risk of death in ppt with systolic HF?

Answer 2

Beta-blockers
ACE OR ARBS
Spirolactone or eplerenone
hydralazine
nitrates

Question 3

(def): data shows no difference between 2 experimental treatments but there is actually a difference

Answer 3

type II error: null hypothesis (assumes there’s no difference) is false

Question 4

(def): confirm efficacy/ effectiveness, monitor side effects, compare it with standard or similar interventions, and collect information about safety

Answer 4

phase 3 study

Question 5

what to use in areas of chloroquine-resistant malaria?

Answer 5

atovaquone-proguanil, doxycycline, or mefloquine

Question 6

active ingredients in malarone?

Answer 6

atovaquone 250mg and proguanil hydrochloride 100mg.

Question 7

products used in allergic conjunctiva?

Answer 7

ketotifen (anti-histamine)
sodium cromoglycate + nedocromil (mast cell stabilizer)

Question 8

products used in dry eyes?

Answer 8

polysorbate

Question 9

used in ocular abrasion to reduce pain

Answer 9

flurbiprofen (NSAID)

Question 10

agent used to reduce eye redness?

Answer 10

naphazoline (vasoconstrictor)

Question 11

good physical exercise for osteoporosis?

Answer 11

regular weightlifting (NOT SWIMING)

Question 12

good physical exercise for osteoarthritis?

Answer 12

regular swimming (NOT WEIGHT-LIFTING)

Question 13

class 100 environment means_______.

Answer 13

no more than 100 particles 0.5 micron or larger present per cubic foot

Question 14

provide examples of Estrogen/Progestogen Combinations for Emergency Contraception?

Answer 14

Alesse (20mcg estrogen + 100mcg levonorgestrol)
MinOvral (30mcg estrogen + 150mcg levonorgestrol)
Triquilar (30mcg estrogen + 125mcg levonorgestrol)

Question 15

how to use alesse for an emergency indication?

Answer 15

-5 tabs to be taken po & another 5 tabs to be taken po after 12 hours

Question 16

how to use minOvral for an emergency indication?

Answer 16

-4 tabs to be taken po & another 4 tabs to be taken po after 12 hours

Question 17

how to use triquilar for an emergency indication?

Answer 17

-4 yellow tabs to be taken po & another 4 yellow tabs to be taken po after 12 hours

Question 18

_______ is money that has already been spent and cannot be recovered.

Answer 18

sunk cost

Question 19

what should be the ACR value range for a case to be diagnosed as a nephropathy?

Answer 19

-higher than 2.0 mg/mmol in men
- higher than 2.8 mg/mmol in women

Question 20

If the PSI score is ≥91, the recommendation is to treat in ________.

Answer 20

hospital

Question 21

Methicillin-susceptible (MSSA) pneumonia is treated with_____

Answer 21

cloxacillin, cefazolin

Question 22

Methicillin-resistant (MRSA) pneumonia is treated with_____.

Answer 22

vancomycin, linezolid

Question 23

often should patients on clozapine perform blood work assessment?

Answer 23

every week for 6 months; after 6 months, tests should be performed every 2 weeks

Question 24

Within 6 months of initiation, these drugs decrease serum PSA levels by approximately 50% in patients with BPH and may partially suppress serum PSA in those with prostate cancer.

Answer 24

5-alpha reductase inhibitors

Question 25

The _________ Questionnaire (mTOQ-4) is a validated tool used to assess a patient’s clinical response to acute therapy

Answer 25

Migraine Treatment Optimization

Question 26

maximum duration of teriperatide?

Answer 26

24months

Question 27

FAST score for Alzheimers?

Answer 27

pre-clinical=3 mild=4 moderate=5 severe= 6 terminal=7

Question 28

The daily dose of clarithromycin should be limited to ________ in patients with severe renal impairment

Answer 28

500 mg

Question 29

antibiotics (with dosage) for community-acquired pneumonia?

Answer 29

ciprofloxacin: 500–750 mg BID PO levofloxacin: Oral: 500 mg Q24H PO × 10 days or 750 mg Q24H PO × 5 days moxifloxacin: 400 mg Q24H PO/IV Azithromycin: PO: 500 mg on the first day then 250 mg daily PO × 4 days or 500 mg daily PO × 3 days Clarithromycin: Regular-release: 500 mg BID PO Erythromycin: 500 mg QID PO Doxycycline: 100 mg BID on first day then 100 mg daily PO

Question 30

what is the maximum permissible dosage of triamcinolone in adults and kids?

Answer 30

Adults and children ≥12 y: 2 sprays (55 mcg/spray) in each nostril once daily, may decrease to 1 spray in each nostril once daily Children 4–11 y: 1 spray in each nostril once daily, may increase to 2 sprays in each nostril once daily if needed. Decrease to 1 spray in each nostril daily for maintenance; maximum 110 mcg/day

Question 31

Respiratory fluoroquinolones include:

Answer 31

levofloxacin & moxifloxacin.

Question 32

provide examples of first-generation antihistamines?

Answer 32

diphenhydramine, dimenhydrinate, doxylamine, chlorphenylramine, azatadine, cyproheptadine, meclizine, cyclizine (*has anti-emetic properties), hydroxyzine

Question 33

provide examples of second-generation antihistamines?

Answer 33

cetrizine, fexofenadine, loratadine, rupatadine, desloratadine

Question 34

unique properties about desloratadine?

Answer 34

decongestant property with minimal emetic property

Question 35

what is the maximum daily dose of gliclazide?

Answer 35

320 mg/day PO; administer in 2 divided doses if daily dose ≥160 mg

Question 36

Hypoglycemic effects in sulfonylurea can be potentiated by ______.

Answer 36

salicylates, sulfonamides and monoamine oxidase inhibitors

Question 37

washout period between when switching from tetracycline to isotretinoin?

Answer 37

7-day period *due to increased risk of high cranial pressure*

Question 38

which PDE-5 inhibitors is affected by fatty meals?

Answer 38

sildenafil (delays Tmax*) Vardenafil (reduces Cmax)

Question 39

which type of hypersensitivity is not managed antihistamines?

Answer 39

type 4 reaction

Question 40

anti-retroviral that should be avoided in patients with positive HLA-B5701?

Answer 40

abacavir

Question 41

T/F: didanosine is used in HIV post-exposure prophylaxis

Answer 41

FALSE!

Question 42

__________is an adrenal steroid synthesis inhibitor that exerts its action by inhibiting steroid 11-beta-monooxygenase

Answer 42

metyrapone

Question 43

_______ is an agent that interferes with the biosynthesis of thyroid hormones by preventing the iodination & proteolytic release of thyroid hormones.

Answer 43

SSKI (*saturated solution of potassium iodine)

Question 44

_________ is used to treat certain fertility problems in women. Binds to the follicle stimulating hormone receptor (FSH), which results in ovulation in the absence of sufficient endogenous luteinizing hormone (LH). It also binds the LH receptor, thereby stimulating proper hormone release.

Answer 44

menotropin

Question 45

______ is an agent used in hyperhidrosis and headaches. It interferes with the release of AcH

Answer 45

Onabotulism toxin A (Botox)

Question 46

T/F: Acetaminophen does not interfere with warfarin

Answer 46

false; a dose higher than 2g/day reduces the metabolism of warfarin= increasing INR

Question 47

______ is a monoclonal antibody that targets proteasomes.

Answer 47

bortezomib

Question 48

what is the normal respiratory rate?

Answer 48

10-20 breaths/minute

Question 49

what is the normal resting heart rate?

Answer 49

60-100 beats/minute

Question 50

Somogyi VS dawn phenomenon

Answer 50

Dawn phenomenon happens when hormones your body naturally makes in the early morning (including cortisol and growth hormone) increase your blood sugar. The Somogyi effect also involves a surge of hormones, but it's due to a low blood sugar episode overnight. Dawn phenomenon doesn't happen because of low blood sugar.