Diabetes UofT

Question 1

T/F: Hyper-osmolar hyperglycaemia state has a higher glucose reading than diabetic ketoacidosis?

Answer 1

true; hyperglycaemia is higher in hyperosmolar hyperglycaemic state

Question 2

Glycemic target control for the following conditions:
-Functionally dependent
-Recurrent severe hypoglycaemia
-limited life expectancy
-frail elderly and/or dementia

Answer 2

-functionally dependent: 7.1-8.0%
-the rest of the condition between 7.1%-8.5%

Question 3

food interaction with sulfonylurea ?

Answer 3

-OH use

Question 4

At what renal function is the risk of hypoglycaemia with sulfonylurea the highest?

Answer 4

Risk of hypoglycemia with fasting or eGFR<60ml/min/1.73m2

Question 5

Thiazolidinediones
(Pioglitazone &
Rosiglitazone) are contraindicated in which scenario?

Answer 5

congestive heart failure & bladder cancer

Question 6

Common side effects of Thiazolidinediones
(Pioglitazone &
Rosiglitazone) include?

Answer 6

fractures

Question 7

S.e. of dipeptidyl Peptidase-4 inhibitors (DPP-4) ?

Answer 7

pancreatitis

Question 8

Glucagon-like peptide 1 agoinst (GLP) that can be used in renal failure?

Answer 8

Liraglutide & Dulaglutide (<15ml/min).