fatigue Flashcards
acute fatique
decrease in maximal force or power production in response to contractile activity
anaerobic pathways for ATP
pcr and glycolysis
Pcr re-synthesis of ATP depends on
creatine levels
type 1s use
mitochondria and some glycolsis and PCr
fuel used for type 1s
fat
glycogen depletion rate for type 1 fibers
slow
type 2 use
both mitochondria and glycolysis (some pcr)
fuel used for type 2
both cho and fat but mainly CHO
type 2x use
Pcr and glycolysis
glycogen depletion rate for type 2x
very fast
glycogen is depleted more from which fiber
fiber 2
traid is
the area of ATP demand/use
where do we use ATP
CA Pump
NA - K pump
myosin ATPase
SR
AP
what pathway is relied upon for high intensity exercise
glycolysis
if glycolysis isnt produced fully then
fat becomes ATP source but it is too slow for high intensity exercise
the 3 things involved in the triad is
1, membrance - Ca pump and Na-K pump
2. SR Ca pump
3. sarcomere - myosin ATPase
if atp cant resynthesize fast enough, what builds up
Pi
excessive build up Pi inhibits
cross bridge cycling by reducing myofibillar sensitivity to CA
extra Pi seeps into
SR and binds to CA so that it can leave to initiate cross bridge cycling
-so troponin cant bind to CA
Ca apperance stimulates
glycogenolysis
low Ph
high amount of H
-acidic
high ph
low amount of H
-basic
what does LDH do
converts pyruvate to lactate
hydrogen is being produced when
pyruvate is being converted to lactate and when ATPase releases energy from ATP
lower ph inhibits
bioenergetic enzymes = decrease in ATP production
ROS signals ____ which stimulates
AMPK, PGC1-a
ROS inhibits _
force production because of too much NO, and superoxide production
what affects ROS the most
level of intensity
endurance exercise
prolonged steady state exercise performed for durations between four minutes and four hours, usually at the highest power output for the duration
oxidative pathways for ATP (complete oxidation of glucose
glycolysis, pdh, krebs, ETC
fiber types recruited in endurance training
types 1 and type 2a
pathways used in endurance training
mitochondria and glycolysis
moderate to low intensity exercise uses
fat instead of glycogen
if ATP is resynthesized well then
-Pi doesn’t accumulate
-Ca flow is uniterrupted
-Ros doesnt accumulate
-lactate and ATPase activity stays lower
-H doesnt accumulate
when glycogen gets too low
-Atp supply becomes compromised - dont have enough fuel for glycolysis
- poor CA pump performance - leads to reduced calcium in the sarcoplasm = less glycogenolysis
-poor NA-K pump performance - wont have any AP
-poor delivery of Atp to sarcomere
CHO recommendations for athletes
3-12 g cho/kg bm/ day
light activity is __and needs ___ amount of CHO
low intensity or skill-based exercise
-need 3-5 g/kg/day
moderate activity is __and needs ___ amount of CHO
moderate exercise about 1 hour and needs 5-7 g/kg/day
high intensity is __and needs ___ amount of CHO
endurance program 1-3h a day moderate to high intensity and needs 6-10 g/kg/day
very high intensity is __and needs ___ amount of CHO
extreme commitment 4-5h a day moderate-high intensity and needs 8-12 g/kg/day
if you eat CHO during exercise then
body will burn more dietary CHO and less glycogen
for 1-2 hours, how much dietary CHO should be consumed
30 g/ hour
for 2-3 hours, how much dietary CHO should be consumed
60 g/ hour
for > 2.5 hours, how much dietary CHO should be consumed
90 g/hr
increase in triggers lead to
-mitochondrial biogenesis
-angiogenesis
-CHO oxidation enzyme (glycolysis, mitochondria)
to increase true anaerobic capacity an athlete needs to increase
PCr
-by eating meat - you get a supply of creatine
