Fat-Soluble Charts Flashcards
beta-carotene
vitamin A precursor made by plants and stored in human fat
orange pigment
breaks into two molecules of vitamin A
Vitamin A function, deficiency, sources
function: maintains cornea, light detection in retina, protein synthesis & cell differentiation, antioxidant
deficiency: hypovitaminosis A; impaired cell differentiation and maturation, epithelial cells flatten and ketatinize, progressive blindness (xeropthalmia), infections, dry salivary glands, less mucous in GI tract
sources: milk, cheese, fortified cereals, fruits, veggies
Vitamin A toxicity
RBC breakage, nosebleeds, headache, impaired growth, digestive system disturbance, absence of menstruation, dry skin, hair loss
vitamin A and cornea/retina
maintains cornea: hard transparent membrane covering outside of the eye
retina: layer of lightsensitive nerve cells in back of the eye; rods and cones
night blindness
slow recovery of vision after exposure to flashes of light at night; early symptom of vitamin A deficiency
xerosis
drying of the cornea; early symptom of xeropthalmia
keratomalacia
total blindness; last and most severe stage of xeropthalmia
follicular hyperkeratosis
accumulation of hard keratin around hair follicles
carotenemia
yellowing of skin caused by excess carotene in the blood
mucous membranes lining eyelids do not turn yellow like in jaundice
teratogenic
vitamin D facts
more like a hormone
not essential if you get enough sun (20 min on face/forearms)
precursor made from cholesterol in liver (UV rays convert to 2nd precursor)
kidney/liver disease = deficiency
vitamin D function, deficiency, sources
function: mineralization of bones
deficiency: rickets/osteromalacia; decreased blood calcium/phosphorus, abnormal growth, soft bones, misshapen bones, muscle spasm
sources: sunlight, fortified milk, butter, eggs, cereal, sardines
vitamin D toxicity
raised blood calcium/phosphorus, kidney stones, thirst, headache, irritability
rickets
vitamin D deficiency disease in children
osteomalacia
bone disease characterized by soft bones
bending of the spine and bowing of the legs
adults
osteoporosis
porous bones, reduced density of bone, adult bone loss
vitamin E function, deficiency, sources
function: antioxidant, stabilize cell membranes
deficiency: muscular dystrophy, RBC hemolysis, fibrocystic breast disease, intermittent claudication
sources: PUFA, leafy greens, wheat germ, nuts, seeds
muscular dystrophy
hereditary: muscles gradually weaken, worst effect on lungs
vitamin E deficiency: gradual paralysis of muscles
erythrocyte hemolysis
bursting of RBC due to lack of vitamin E
fibrocystic breast disease
harmless condition where lumps form in the breasts
caffeine abstinence helps or increased vitamin E
intermittent claudication
severe calf pain caused by inadequate blood supply
occurs when walking, stops when resting
vitamin K facts
we synthesize 50%
essential for activating 7 blood clotting proteins (prothrombin)
vitamin K function, deficiency, sources
function: synthesis of blood-clotting proteins and a protein that binds calcium in bones
deficiency: hemorrhagic disease
sources: leafy greens, milk, cabbage, synthesize in gut
vitamin K toxicity
interferes with anti-clotting medications
jaundice, RBC hemolysis, brain damage
when does vitamin K deficiency occur?
fat malabsorption or no bile
after antibiotics kill gut bacteria
ACE
vitamins that are antioxidants