Eyes Flashcards

1
Q

Three layers

A

Schleroid
* White of the eye
* Continuous with cornea

Choroid
* Blood vessel layer
* Iris and ciliary body

Retina
* Back and sides only
* photoreceptors

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2
Q

Vitreous and Aqueous Humour

A

Vitreous humour (behind lense)
-Gelatinous, thick
-Maintains shape of eye

Aqueous humour
-Provides nutrients to the cornea
- 5 mL/day, comes through front of lease

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3
Q

Glaucoma

A

-Blocked drainage duct

-Aqueous humour fluid builds

-Build-up of pressure, eye gets elevated pressure

  • Can damage nerve

-throws off sizes and causes blurry vision

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4
Q

Iris and Pupil

A

Pupil
-Eye opening for light

Iris
-Colour of the eye
-Controls amount of light entering eye

  • Circular muscles constrict pupil (get smaller, limit light)
  • Radial muscles dilate pupil (pulls them open, done in dark)
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5
Q

Convex structures of eye produce
convergence of diverging light rays that reach eye

A

defracting pattern
- bent in
-diverging

Images formed on the retina are upside down and are only a small fraction of the object’s actual size

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6
Q

Refraction is a result of

A

Cornea, doesn’t bend
* Contributes most to refraction
* Refractive ability remains constant because curvature never changes

Lens
* Refractive ability can be adjusted by changing curvature as needed for near
or far vision
- allows focus of near/far

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7
Q

Accommodation

A

For far vision
-Light rays are parallel – need less bending
-Lens should be flatter, doesn’t need to be as strong

For near vision
-More bending needed, focus on retina
-Rounder lens, fatter and rounder

contracted = lower tension and more rounded lens

relaxed = higher tension and more flattened lens

Involves:
-Ciliary muscles - changes lens
-Suspensory ligaments - springs of trampoline

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8
Q

Near vs Far accommodation

A

For far vision
-Ciliary muscles relax
-Suspensory ligament are pulled taut (tight)
-Lens is flatter / weaker

For near vision
-Ciliary muscles contract
-Suspensory ligaments go slack
-Tension in lens causes it to become rounder/stronger

at rest=far vision

out of focus is going from far to near and light rays don’t bend in time due to changing lens shape

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9
Q

Lenses

A

Convex lens
-convergent
-Bends light rays in
-Eg. Lens of eye

Concave lens
-divergent
-Bends light rays out

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10
Q

Eye conditions

A

Emmetropia
-Normal vision

Myopia (can’t see far)
-Near-sightedness
-Lens is too strong or eye
too long (bending rays too much)
-Focus is in front of retina
-Corrected with a concave lens
- prescription makes lenses weaker

Hypermetropia or hyperopia
-Far-sighted-ness (only see far)
- Lens too weak or eye to short (not bending enough)
-Focus is behind retina
-Corrected with a convex lens
- prescription makes lenses stronger

-want focus on retina

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11
Q

Presbyopia

A

-Loss of near vision with age
Due to stiffening of lens
-Harder to become round
-Correct with reading
glasses

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12
Q

Light transduction

A

Light transduction occurs on the retina
- from light rays to electrical impulses

Photoreceptors
- Rods and cones

Bipolars

Ganglions

Optic nerve

From light waves to rods and cones then back to bipolar cells then ganglia and then out blind spot

Horizontal cells – lateral inhibition (acuity)
Amacrine cells – assist?

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13
Q

Retinal layers and Retina

A

Retinal Layers
-Light must filter through cell layers before hitting the rods and cones
- Blind spot – where optic nerve leaves eye

Retina:

Fovea
-Pinhead-sized depression in centre of retina
-Most distinct vision
-Has only cones (no filtering)
-no ganglia or rods

Macula lutea
-Area immediately surrounding
fovea
-High acuity
* cones only – but with overlaid
bipolars and ganglions
-2nd best visual

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14
Q

Macular Degneration

A

Macular degeneration
-Loss of cones in macula
- Lose central vision

  • Leading cause of blindness
    in western hemisphere (peripheral)
    “doughnut” vision

Wet – more blood vessels – bleeding
Dry – atrophy of pigment

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15
Q

Properties of Rod and Cone vision

A
  1. Rods - peripheral vs Cones - central (fovea and macula lutea)
  2. Rods = 100 million per retina vs Cones = 3 million per retina
  3. Rods = vision in shades of grey vs Cones = colour vision, 3 main types
  4. Rods = high sensitivity, low acuity vs Cones = low sensitivity, high acuity
  5. Rods are night vision, Cones is day vision
  6. Rods = Much convergence in retinal
    pathways vs Cones =Little convergence in retinal pathways
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16
Q

Rods vs Cones

A

Rods - many convergence in retinal

-100:1 wiring (rods to bipolars)
* Low light needed to stimulate 1 bipolar. Don’t know where light source

-Larger receptor field
* Poor acuity (high sens)

Cones - little convergence in retinal

-1:1 wiring
* Need a lot of light for AP Small receptor field (know where light from)

  • High acuity (low sens)
17
Q

Photopigments

A

Photopigments
Rod pigment
-Provide vision only in shades of grey
Rhodopsin
* Absorbs all/most visible wavelengths (spectrum)

Cone pigments
-Colour Vision
* Red cones
* Green cones
* Blue cones

-red and green close in spectrum

Chemical change when activated by light (pigments brokendown)

Consists of two components:

Opsin
* Protein that is integral part of disc membrane
Retinene
* Derivative of vitamin A
* Light-absorbing part of photopigment

18
Q

Resting state in dark

A

Na+ gates are open
-Rods and cones are depolarized
-Release inhibitory NT
* glutamate (inhibitory in eye)
-Bipolar cells are inhibited
-No AP’s to ganglions / optic nerve

19
Q

In light

A

Light breaks down photopigment

Closes Na+ gates
Hyperpolarizes membrane
Decreases inhibition of bipolars
* Bipolars excited -GP too
* GP’s to ganglions
* AP’s to Optic nerve

20
Q

Events in Photoreceptor in Response
to a Light Stimulus that Initiate An AP
in Visual Pathway

A

RODS

-Light which activated photopigment
- Leads to decrease in cyclical GMP
- Close of sodium channels
- Membrane is hyper polarized
- Closes Ca channels in synaptic terminal
-Release of inhibitory transmitter
- Bipolar neurones disinhibited
-Graded potential change in bipolar cell
- AP in ganglion cell

21
Q

In Cones

A
  • Different patterns of AP for colour
  • Responding to light
  • Remember colour with response to identify of action potentials
22
Q

Colour blindness

A

Poor or lack of function in one or more
colour cones

Protanopia
* Lack or red cones
Deuteranopia
* Lack of green cones
Tritanopia
* Lack of blue cones

Poor function of cones
Protanomaly
* Poor red funcion
Deuteranomaly
* Poor green function
Tritanomaly
* Poor blue function

23
Q

Dark adaptation

A

Go from light to dark
Re-form more photopigment
* Changes threshold (lower if make more)
-Eyes become more sensitive (rods)
-More rods used
-Vitamin A needed for regeneration
Eg. Entering movie
theatre

24
Q

Light adaptation

A

When you go from dark to bright light
Sudden break-down of photo-pigment
* Bleaching
Eyes become less sensitive with less
photopigment (adapt but leave broken down)
Eg. Walking outside after a movie

25
Q

Optic Chaism

A

This is the neuroanatomical
pathway responsible for processing
visual information;

the visual association cortex is responsible for visual illusions

Upside down and opposite (backwards)

View stitches at optic chaism. left view goes to right retina