Autonomic Nervous system Flashcards
Autonomic Nervous system
Automatic reflex, two antagonist branches
-control of cardiac and smooth muscle and glands in homeostasis
Sympathetic: fight or flight, adrenalin rush. Increased BP and HR, adrenalin released
Parasympathetic: rest and digest, slower hr and lower bp
Balance between two at all time
The Hypothalamus, Pons, and Medulla
Hypothalamus: Hormones
Pons: breathing
Medulla: HR and breathing
Coordination of homeostatic responses
-Autonomic
-Endocrine
-Behavioural
Autonomic Branches
Sympathetic neurons:
Short pre-ganglionic neurons
Long post-gangionic neurons
Ach at ganglion, Epinephrin at Effector organ
Parasympathetic neurons
Long pre-ganglionic neurons
Short post-ganglionic neurons
Ach at ganglion and effector organ
Cholinergic Receptors
Bind Acetylcholine
Nicotinic receptors found at the
-Sympathetic Ganglia
-Parasympathetic Ganglia
-Neuromuscular junction (skeletal muscle)
Muscarinic Receptors found at the
-Parasympathetic effector organs
Adrenergenic Receptors (Alpha)
Alpha 1 (epi and norepi)
-Vasoconstricts blood vessels – heart, muscle, gut, kidneys, skin
-Increased sweat gland secretion/goose bumps
-Dilates pupils
-Propels urine
Alpha 2 (epi and norepi)
-Inhibits insulin release / constricts gut sphincters
-Decreases norepinephrine release
Adrenergenic Receptors (Beta), exercise
Beta 1 (epi and norepi)
Increases heart rate and contractility
Increased renin from kidney
Beta 2 (only epi)
Vasodilates blood vessels – muscle, heart
Bronchodilation
Relaxes gut wall and uterus
Beta 3
Lipolysis – fat tissue
Relaxes bladder
Somatic vs Autonomic
Somatic:
1. Consists of a single neuron between CNS and skeletal muscle cells
2. Innervates only skeletal muscle
3. Only excitation
Autonomic:
1. Two-neuron chain (connected by a synapse) between CNS and effector organ
2. Innervates smooth and cardiac muscle, glands and GI neurons
2. Inhibitory vs Excitatory
Sympathetic vs Parasympathetic locations
Sympathetic: Thoracic and
lumbar regions
Parasympathetic: Cranio-sacral
Sympathetic effects
↑ heart rate and contractility
↑ breathing rate and depth
Blood vessel effects
Vasoconstriction to non-essentials (eg. Gut)
vasodilation to muscle
↓ Gut activity and secretions
↓ kidney function and urine output
Pupil dilation
Parasympathetic effects
↓ heart rate and contractility
↓ breathing rate and depth
NO EFFECT ON BLOOD VESSELS
↑ Gut activity and secretions
↑ kidney function and urine output
Pupil constriction