Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

2: ENRP Exam 1 > Extras: Repro Path and Clinical > Flashcards

Extras: Repro Path and Clinical Flashcards

1
Q

vulvar vestibulitis

A

vestibular gland infection -> erythematous dots that are severely painful

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what causes lichen simplex chronicus vs lichen sclerosis

A
  1. simplex chronicus: chronic itching/rubbing

2. lichen sclerosis: inflammatory disorder with T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

lichen simplex chronicus histo vs lichen sclerosis

A
  1. simplex chronicus: thickened epidermis, hyperkeratosis, elongated rete ridges
  2. lichen sclerosis: thinning, edematous band with lymphocytes, loss of rete ridges
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cause of VAIN

A

HPV 16, 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

mets of vaginal SCC from lowr vs upper vagina

A
  1. lower -> inguinal LNs

2. upper -> regional iliac LNs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

gartner duct vs mullerian cyst origin

A
  1. gartner duct: mesonephros remnants

2. mullerian: paramesonephros

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

histo of acute vs chronic endometritis

A
  1. acute: neutrophils

2. chronic: plasma cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what causes uterus didelphys**

A

failure of Mullerian ducts to fuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how to Dx endometrial hyperplasia in a post-meno woman

A

Bx: endometrium >4mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

types of endometrial carcinoma in type 1 and 2

A

type 1: endometrioid

type 2: MMMT, serous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

RFs for type 1 vs type 2 endometrial carcinoma

A
  1. type 1: unopposed E, obesity (younger age)

2. type 2: age, atrophy, black pts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

which type of endometrial carcinoma has a better prognosis?

A

type I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is JAZF1 gene mutation associated with?

A

Endometrial stromal sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mutation seen in most leiomyomas

A

MED12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

four tx options for leiomyomas

A
  1. E + progesterone
  2. progesterone only
  3. GnRH agonists
  4. surgry
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

three things on histo of leiomyosarcoma

A

atypica, mitoses, tumor necrosis

17
Q

five epithelial tumors of the ovary

A
  1. serous cystadenoma
  2. mucinous cystadenoma
  3. endometrioid
  4. clear cell tumor
  5. Brenner’s tumor
18
Q

RFs for serous cystadenoma of the ovary

A

BRCA1/2

19
Q

mucinous cystadenoma is assoc with what + what mutation?

A

appediceal mucocele; KRAS mutation

20
Q

six types of germ cell tumors of the ovary

A
  1. dermoid cyst
  2. immature malignant teratoma
  3. monodermal teratoma
  4. dysgerminoma
  5. yolk sac tumor
  6. choriocarcinoma
21
Q

dermoid cyst

A

mature cystic teratoma - histo of all three embryonic layers

22
Q

how is immature malignant teratoma different from dermoid cyst

A

immature malignant also has neuroepithelium along with teratoma

23
Q

two types of monodermal teratomas

A

carcinoid tumor, struma ovarii

24
Q

what ovarian tumor produces AFP

A

yolk sac tumor

25
Q

four types of sex cord stromal tumors of ovaries

A
  1. granulosa cell tumor
  2. thecoma
  3. fibroma
  4. sertoli-leydig cell tumor
26
Q

granulosa cell tumor gross + histo

A

yellow (bc H’s); coffee bean nuclei on histo

27
Q

what types of ovarian tumors secrete inhibin?

A

sex cord stromal tumors, esp granulosa cell tumors

28
Q

ovarian tumor with DICER1 mutation that secretes T

A

sertoli-leydig cell tumor

29
Q

CAD: congenital adrenal hyperplasia

A

defect in 21-hydroxylase -> excess androgen -> born with ambiguous genitalia or have precocious heterosexual puberty

30
Q

two conditions that cause pseudoisosexual precocious puberty

A

mccune-albright syndrome, Peutz-Jegher’s

31
Q

what does KAL mutation -> Kallman’s syndrome cause

A

GnRH neurons cant migrate to hypothalamus -> hypogonadotropic hypogonadism

32
Q

one example of hypergonadotropic hypogonadism

A

Turner Syndrome

33
Q

MC cause of primary amenorrhea in pt with normal secondary sex characteristics

A

Mullerian Agenesis

34
Q

to Dx PCOS, need 2/3..

A
  1. oligo/amenorrhea
  2. signs of hyperandrogenism or LH:FSH 2:1
  3. US shows small cysts on ovaries

2: ENRP Exam 1 (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions