21: Medical Complications in Pregnancy Flashcards
screening for gestational DM
50gm glucose drink in one hour -> values 130+ are abnormal
next step if pts gestational DM test is abnormal
3 hour 100gm oral glucose tolerance test
maternal complications of gestational DM
gestational HTN, preeclampsia, DM later in life (70%)
fetal complications of DM in pregnancy
birth defects**, SAB, IUGR, prematurity
Class A1 and A2 gestational DM
A1: gestational DM, diet controlled
A2: gestational DM, insulin or oral meds controlled
med options for DM in pregnancy
insulin -> metformin
two meds that can be used for maternal hyperthyroidism
PTU, methimazole
biggest risk of maternal hyperthyroidism meds
can cause fetal goiter -> cant deliver vaginally
S/S thyroid storm
hyperthermia, tachy, perspiration, high output cardiac failure, maternal mortality of 25%
untx hypothryoid in pregnancy
SAB, preeclampsia, abruption, low birth weight infants, stillbirth
neonatal thyrotoxicosis
transplacental transfer of thyroid stimulating Abs (transient)
primary pulmonary HTN and pregnancy
pregnancy contraindicated bc decompensation -> high mortality rate
MC cardiac arrhtymia in pregnancy
SVT
best thing for pregnant cardiac pts**
co-management with a cardiologist
tx for immune idiopathic thrombocytopenia
prednisone
fetal complications of SLE
preterm delivery, IUGR, miscarriage, neonatal lupus
fetal complications of Anti-phospholipid syndrome
miscarriage, preeclampsia, IUGR
what causes asymptomatic bacteriuria
urinary stasis, glucosuria -> E coli MC organism
hyperemesis gravidaru
N/V persistent, >5% loss of pre-preg weight, ketonuria, dehydration
Chron and UC in pregnancy
usually do pretty well, only issue is possible nutrition deficits
ICP: intrahepatic cholestasis of pregnancy
cholestasis and pruritis in 2nd half of pregnancy - benign for mother but increased risk of fetal demise
treatmet for ICP
ursodeoxycholid acid, cold baths, but nothing helps fetal state
Acute fatty liver of pregnancy: cause and sx
cause unknown -> abd pain, N/V, jaundice, irritability, HTN
acute fatty liver of pregnancy treatmet
termination of pregnancy bc maternal and fetal mortality are high