15: Pap Smear

Question 1

two types of epithelia on the cervix

Answer 1

columnar, statified squamous

Question 2

four HPVs that cause the majority of cancer

Answer 2

16, 18, 31, 45

Question 3

RFs for cervical neoplasia

Answer 3

multiple sex partners, smoking, organ transplant, STIs, DES, high parity

Question 4

descripe colposcopy

Answer 4

wash cervix with acetic acid -> visualize cervix with stereomicroscope, looking for acetowhite changes, punctation, mosaicism, abnormal vessels, masses

Question 5

ablative vs excisional treatmnt for cervical CA

Answer 5

1. ablative: cryotherapy, laser ablation

2. excisional: cold knife cone, LEEP

Question 6

what does LEEP stand for

Answer 6

loop electrode excisional procedure

Question 7

risks that come with excisional procedures on the cervix

Answer 7

cervical incompetence during pregnancy and resultant second trimester loss, PPROM, cervical stenosis

Question 8

how long does it take for precursor lesion to become invasive carcinoma

Answer 8

about 10 years (slow growing)

Question 9

sx of cervical carcinoma

Answer 9

watery vaginal bleeding, post-coital bleeding, intermittent spotting

Question 10

two best ways to prevent cervical CA

Answer 10

1. barrier protection

2. HPV vaccine**

Question 11

who gets the HPV vaccine

Answer 11

all genders ages 9-26

Question 12

dosing of the HPV vax

Answer 12

first dose -> 2nd dose 2 months later -> 3rd dose 4 months after 2nd