export_bact test 6 Flashcards
d
e
Fusobacteriumnecrophroum
Usual cause of hepatic abscesses in feedlot cattle
Clostridium perfringens Type A, Clostridiums perfringens type CClostridium difficile
According to the required reading, what are the 3 most common clostridium involved in diarrhea diseases in baby pigs
Porphyromonas, Prevoteilla
2 genera that contain most of the species of Black-pigmented obligately anaerobic bacteria
Clostridium botulinum type C
You are a wildlife vet in oregon. You are studying the cause of death of 1000 ducks in some shallow ponds in a wildlife refuge. The major symptom you saw was a flaccid paralysis w/o recovery in the birds. One bacteria known to cause this type of disease is?
Clostridium tetani
This agent causes a toxin that will cause a generalized rigid spastic paralysis of skeletal muscle in affected dogs
Clostridium haemolyticum
Fever, anemia, hemoglobinuria were observed in 4 cows from a herd of 50 Holstein cows in Wisconsin. Lesions(one cow died) of anemia and a large liver infarct were seen at necropsy. Large gram positive sporeforming rods were isolated from liver on anaerobic culture
Clostridium botulinum Type C
This agent produces a toxin that causes a generalized flaccid paralysis in ducks and other avian species when ingested from environmental sources
Clostridium perfringens Type D
This gram positive obligately anaerobic sporeforming bacteria is the cause of one type of bovine enterotoxemia in feedlot cattle that usually results in sudden death. In the live animal, it is characterized by symptoms of CNS disease
Clostridium novyi
The cause of infectious necrotic hepatitis in cattle
Clostridium piliforme
Animal: 3 wk old foal in MO
Symptoms: Foal died suddenly
Lesions: Multiple foci of hepatic necrosis were seen
Lab: No growth on aerobic blood agar
Histo: Large filamenious bacteria arranged in parallel fashion in hepatocytes were seen on a silver stain of a liver lesion
Clostridium perfringens Type A
Bacteria commonly associated w/ canine hemorrhagic gastroenteritis
Clostridium Perfringens Type C
This agent produces a toxin that causes a necrosis of intestinal epithelium in neonatal foals
Clostridium piliforme
Considered to be the cause of Tyzzer’s disease in mice
Clostridium botulinum Type B
Animal: well-nourished 3 week old foal in KY
Syptoms: Generalized flacid paralysis of major skeletal muscele masses
Foal rfails to respond to stimuli
Lesions: gastric ulcers were observed
Clostridium perfringens type C
Animals: two neonatal calves
Symptoms and lesions> sudden death, small intestine had signs of a necrotic bloody enteritis
Lab: large gram positive rods observed in direct smear
Bacillus anthracis
Animals: Group of 50 yearling cattle in Tx
Symptoms: sudden death in 2 animals
Necropsy: blood didn’t clot, spleen is enlarged
Lab: Large sporeforming gram positive rod grew on primary aerobic culture
Clostridium perfringens Type A
Animal: 3 yr old Beagle in Columbia
Symptoms: Dog is in acute shock and has a bloody diarrhea
Lab: Direct smear of bloody feces, large gram positive rods on majority population
Fusobacteriumnecrophorum
and
Porphyromonas levii
These 2 species of bacteria act as synergistic agents in pathogenesis of acute foot rot
Bacillus anthracis
This agent is the cause of anthrax in hores
Clostridium chauvoei
Animal: Yearling well-nourished steer in Missouri
Symptoms: sudden death
Lesions: Gas bubbles under skin of left hidnd leg, large dry dark area in muscle of the leg
Your diagnosis: Blackleg
Clostridium difficile
This species of gram positive sporeforming rod was originally associated w/ antibiotic induced overgrowth digestive tract disease in humans. Subsequently it was identified as a cause of the same type of disease in lab animals and has recently ibeen identifed as a cause of a severe hemorrhagic necrotizing enterocolitis in neonatal foals
Bacillus anthracis
Clostridium botulinum type A
Two bacteria from 2 different genera that are considered by the CDC to be class A bioterrorism agents
Fusobacteriumnecrophorum
Animals: herd of 200 dairy cows in MO
Symptoms: chronic lameness in about 50 of the cows w/ involvement of 2-4 feet
Lesions: interdigital necrosis and chronic destruction of the bulbs of the feet
Diagnosis?
Propionibacterium acnes
This agent is commonly used in products sold as immunomodulators
Binary fission
Term that would describe the method of reproduction of Bacillus anthracis
Dipicolinic acid
Compound found in the core of endospores that may be responsible for its environmental resistance
Septate hyphae
The type of hyphae that are characteristic of the Deutoromycetes
Catalase
Superoxide dismutase
These 2 enzymes produced by certain bacteria protect them from toxic oxygen containing compounds produced when oxygen is the terminal electron acceptor in energy metabolism
Gingivitis
Inflammation of the gum tissue of the mouth
Deutoromycetes
This form class contains most of the fungi pathogenic to animals
Obligately anaerobic bacteria
How would Clostridium perfringens be classified in regards to utilization of oxygen in their environment?
Gangliosides
These gylcosphingolipids are components of the cell plasma membrane which modulate cell signal transduction events
Cytochrome systema
These proteins are important in electron transport in the presence of oxygen
Myositis
Inflammation of the muscles
Endemic
Term referring to a persistence of infection or disease in an animal population at a more or less constant low level
Reducing agents
These compounds are used to remove oxygen from media
Eh
Term that is used to express oxidation reduction potentials
Chitin
This compound is a structural component of the cell wall of fungi but not of bacteria
Embden Meyerhoff pathway
This biochemical pathway is responsible for anaerobic glycolysis of glucose
Anoxia
If an animal died due to a lack of oxygen in his system, we would say this animal died of?
Prebiotics
Complex carbs that are given to stimulate the growth and/or activity of bacteria in the digestive system which are beneficial to the health of the body
Prebiotics
Complex carbs tat are given to stimulate the growth and or activity of bacteria in the digestive system which are beneficial to the health of the body
Crepitation
A crunching crackling sensation that is felt w/ gas production by bacteria in tissues
Pyogenic
Bacterial infections that are characterized by pus formation and abscesses
Endotoxin
When a label on an injectable vial states that the contents are pyrogen free it means that the contents do not contain?
Ergosterol
This compound is in the plasmalemma but not in mammalian cell structures
Conjugation
The name for the process which refers to the transfer of genetic elements b/t bacteria that is mediated by bacterial pili
Krebs cycle
This biochemical pathway is the major energy producing pathway in facultatively anaerobic bacteria but is not present in obiligately anaerobic bacteria
Liver
What organ serves as the principal site of infection for Clostridium haemolyticum infection in cattle?
Liver
What is the organ that serves as the principal site of infection for Clostridium piliforme infection in mice?
SI
What is the organ that serves as the principal site of infection for neonatal enterotoxemia in pigs?
LI
What is the organ that serves as the principal site of infection of clostridium difficile infections in humans?
Commercial toxoid
You have an owner who wishes to prevent necrotic abomasitis in his calves
Commercial antitoxin
You have just castrated a horse w/ an unknown vaccination history. You wish to prevent tetanus
Commercial bacterin or whole culture bacterin
You have an owner who wishes to prevent periodontal disease in his dogs
Commercial toxoid
You have an owner who wishes to prevent toxicoinfectious botulism in his horses
Commercial toxoid
You wish to vaccinate a horse for long term prevention of tetanus
Commercial Modified or avirulent live vaccine
You have horses that you want to vaccinate to prevent anthrax
Commercial bacterin or whole culture bacterin
You have an owner who wishes prevent blackleg in his feedlot steers
Commercial bacterin toxoid combo
You have an onwer who wishes to vaccinate his cows to prevent neonatal enterotoxemia in his calves
Jugular blood sample
The best tissue for bacteriolgocialcultureto send to a diagnostic lab from an 800 lb dead steer that you suspect has anthrax would be?
Demonstrationof bacteria on histopathology
Which of the following would be the most important procedure in the routine confirmation of a diagnosis of Tyzzer’s disease in a foal
Bacteriocidal and time dependent
Cephalosporins in regards to use in the patient and action on the bacteria are?
Cell wall synthesis
Cephalosporins in regards to site of action in the bacteria affects?
Gram negative non-sporeforming anaerobic rod
A description of Bacteroides fragilis would be?
Growth stimulant
Carbon dioxide
Catalyst
Palladium
Chemical indicator of Eh
Resazurin
Reducing agent
sodium Thioglycoliate
Endotoxins
The inciting lesions allowing bacterial overgrowth in canine hemorrhagic gastroenteritis are probably due to this toxin
Lethal factor
A major toxin of Bacillus anthracis
Epsilon toxins
Major toxin produced by Clostridium perfringens Type D
Beta toxins
Major toxin produced by Clostridium perfringens type C
Metronidazole
Drug of choice to treat a Clostridium difficile inefection in a horse
Amoxicillin
Drug of choice for treatment of acute foot rot in dairy cattle
Gentamicin
This drug has long term residues in the kidneys of cattle such that vets recommend that the drug not be used to treat feedlot cattle even though it can be legally used for treatment
Amoxicillin
Drug of choice for treatment of clostridial myositis in a horse
Enrofloxacin and Gentamicin
2 antimicrobialswhich are commonly used to treat bacterial infections but which are unlikely to wwork against anaerobic bacteria
Amoxicillin
Drug of choice for treatment of Anthrax in a dog
Tilmicosin
This macrolide drug used to treat cattle and swine is known for having significant toxicity on accidental injection in humans
Amoxicillin
Clavulanic acid is used as a potentiator in combo w/ this drug
Antimicrobialsdont work/fit the given description
Drug of choice for treatment of Tyzzer’s disease in a horse
Clostridium chauvoei
Animal: Yearling well-nourished steer in Missouri
Symptoms: Sudden death
Lesions: Gas bubbles under skin of left hind leg, large dry dark area in muscle of the leg.
Your diagnosis: Blackleg
Clostridium novyi
Cause of infectious necrotic hepatitis in cattle
Clostridium tetani
Animal: 3 yr old QH
Symptoms: Uncontrolled paraoxysomal spasms of major muscle masses brought on by a randomstimulus leading to a temporary rigid paralysis
Clostridium botulinum Type B
Cause of Toxicoinfectious botulism in horses
Clostridium perfringens Type C
This agent produces a toxin that causes a necrosis of intestinal epithelium in neonatal foals
Clostridium piliforme
Considered to be the cause of Tyzzer’s disease in horses
Clostridium botulinum Type B
Cause of toxicoinfectious botulism in horses
Clostridium perfringens type C
This agent produces a toxin that causes a necrosis of intestinal epithelium in neonatal foals
Clostridium piliforme
Considered to be the cause of Tyzzer’s disease in horses
Clostridium botulinum Type B
Animal: Well nourished 3 week old foal in KY
Symptoms: Generalized flaccid paralysis of major skeletal muscle masses
Foal fails to respond to stimuli
Lesions: Gastric ulcers were observed
Clostridium botulinum Type C
This agent produces a toxin that causes a generalized flaccid paralysis in ducks and other avian species when ingested from environmental sources
Clostridium Botulinum Type C
This agent produces a toxin that causes a generalized flaccid paralysis in ducks and other avian species when ingested from environmental sources
Clostridium Perfringens type C
This agent produces a toxin that causes a necrosis of intestinal epithelium in neonatal foals
Clostridium perfringens type A
Bacteria commonly associated w/ canine hemorrhagic gastroenteritis
Clostridium tetani
This agent produces a toxin that will cause a generalized rigid spastic paralysis of skeletal muscle in affected dogs
Porphyomonasdenticanis
Porphyromonas gulae
Porphyromonas salivosa
These 3 agents are considered to be important in periodontal disease in dogs and are included in bacterin to prevent this disease
Clostridium perfringens type C
Animals: group of neonatal pigs
Symptoms: sudden death, SI shows signs of a necrotic bloody enteritis
Lab: Large gram positive rods observed in direct smear
Fusobacteriumnecrophorum
Usual cause of hepatic abscesses in feedlot cattle
Clostridium botulinum Type C
You are a wildlife vet in the northwest. You are studying the cause of death of 3000 birds in some shallow ponds near watercourses. The major symptom you saw was a flaccid paralysis w/o recovery in the birds. One bacterium known to cause this type of disease in the NW is?
Clostridium perfringens type D
This gram positive anaerobic sporeforming bacteria is the cause of the type of bovine enterotoxemia, characterized by sudden death, or if the animal lives it is characterized by symptoms of CNS disease
Clostridium perfringens Type A
Animal: 2 year old german shepherd in KC
Symptoms: Bloody diarrhea, acute shock
Lab:
Lab: direct smear of bloody feces, large gram positive rods are majority poplation
Fusobacteriumnecrophorum
Dichelobacter nodosus
Animal: flock of 100 sheep in MO
Symptoms: Chronic lameness in about 50 of the sheep in 204 feet on each sheep
Lesion: Interdigital necrosis, chronic destruction of the bulbs and overgrowth of horn in many nanimals
Diagnosis: contagious digital epidermatitis/chronic foot rot
(2 agents)
Propionibacterium acnes
This agent is commonly used in products sold as immunomodulators
Fusobacteriumnecrophorum
Porphyromonas levii
These 2 species of bacteria act as synergistic agents in pathogenesis of acute foot rot in cattle
Bacillus anthracis
Clostridium botulinum
These 2 bacteria from 2 different genera are considered by the CDC to be Class A bioterrorism agents
Bacillus
Clostridum
2 gernea of gram positive spreforming bacteria
Binary fission
Term used to describe the method of repro of Clostridium perfringens
Eh
Term that is used to express oxidation reduction potentials
Conjugation
Name for the process which refers to the transfer of genetic elements b/t bacteria that is mediated by bacterial pili
Ergosterol
This compound in the plasmalemma but not in mammalian cell structures
Sepsis
A systemic inflammatory response resulting in a severe toxic febrile state due to infection w/ pyogenic bacteria w/ or w/o an associated septicemia
Bacteria
In classification, to which domain do the bacteria belong?
Endotoxin
When a label on an injectable vial states that the contents are pyrogen free it means that the contents do not contain?
Periodic-Acid-Schiff stain
You have submitted a tissue specimen to a diagnostic lab. You request that they stain a histopathologic slide specifically for the cell wall of fungi. They would probably use this stain
Crepitation
A crunching crackling sensation that is felt w/ gas production by bacteria in tissues
Reducing agents
These compounds are used to remove oxygen from media
Toxoids
Product containing specific inactivated exotoxins and used for immunization of animals against these exotoxins
Gangliosidosis
These glycosphingolipids are components of the cell wplasma membrane which modulate cell signal transduction events
Dipicolonic acid
Compound found in the core of endospores that mayb be responsible for its environmental reseistance
Obligately anaeerobic bacteria
How would clostridium pefringens be classified in regards to utilization of oxygen in their environment?
Endemic
Term referring to a persistence of infection or disease in an animal population at a more or less constant low level
Catalase
Superoxide dismutase
These 2 enzymes produced by certain bacteria protect them from toxic oxygen containing compounds produced when oxygen is the terminal electorn acceptor in energy metabolism
Amoxicillin
Drug of choice for treatment of clostridial myositis in adog
Sulfadiazine
Trimethoprim is used as a potentiator in combo w/ this drug
Amoxicillin
Clavulanic acid is used as a potentiattor in combo w/ this drug
Amoxicillin
Drug of choice for treatment of blackleg in cattle
Antimicrobialsdo not work/ fit in the described condition
Drug of choice for treatment of Tyzzers disease in a horse
ofulvin
This agent should not be used in pregnant queens because it may cause teratogenic effects
Amoxicillin
Drug of choice for treatment of anthrax in a horse
Enrofloxacin
This agent must be used w/ caution in cats because use above 5 mg/kg can cause retinal degeneration
Enrofloxacin
Gentamicin
2 antimicrobialswhich are commonly used to treat bacterial infections but which are unlikely to work against anaerobic bacteria
Commercial toxoid
You wish to vaccinate a horse for long term prevention of tetanus
Commercial bacterin or whole culture bacterin
You have an owner who wishes to prevent Bacillary Hemoglobinuria in his cattle
Commercial bacterin or whole culture bacterin
You have just castrate a horse w/ an unknown vaccination history. You wish to prevent tetanus
Commercial bacterin or whole culture bacterin
You have an owner who wishes to prevent periodontal disease in his dogs
Commercial toxoid
You have an owner who wishes to prevent toxicoinfectious botulism in his horses
Commercial modified or avirulent live vaccine
You have cattle that you want to vaccinate to prevent anthrax
Commercial bacterin toxoid combination
You have an owner who wishes to vaccinate his sows to prevent neonatal enterotoxemia
SI
What is the organ that serves sat the principal site of infection w/ neonatla enterotoxemia in pigs?
Liver
What is the organ that serves as the principal site of infection w/ Clostridium piliforme infection in mice?
LI
What is the organ that serves as the principal site of infection w/ Clostridium difficile infections inhumans
Liver
What is the organ that serves as the principal site of infection w/ clostridium hemolyticum infection in cattle?
Reducing agent
Soidum thioglycollate
Chemical indicator of Eh
Resazurin
Reducing agent
Hydrogen
Catalyst
Palladium
Demo of bacteria on histopath
Which of the following would be the most important procedure in the routine confirmation of a diagnosis of Tyzzer’s disease in a foal?
Liver
Endotoxin is possibly one major etiologic factor in canine hemorrhagic gastroenteritis. The major organ affected by the endotoxin resultin in the symptoms of HGE is?
Gram negative non-sporeforming anaerobic rod
A description of Bacteroides fragilis would be?
Protective antigen
What fraction of the exotoxin Bacillus anthracis is necessary for the activity of the other 2 fractions?
Major infection followed by intoxication
How would you classify disease caused by clostridium tetani?
Alpha toxins
Major toxin produced by all strains of Clostridium perfringens Type A
Lethal factor
A major toxin of Bacillus anthracis
Epsilon toxins
Major toxin produced by Clostridium perfringens type D
Toxins A and B
Major toxin produced by clostridium difficile
Iota toxins
The inciting lesions allowing bacterial overgrowth in Canine Hemorrhagic Gastroenteritis are probably due to this toxin
Commercial toxoid
You wish to vaccinate a horse for long-term prevention of tetanus
Commercial toxoid
You have an owner who wishes to prevent toxicoinfectious botulism in his horses
Commercial antitoxin
You have just castrated a horse w/ an unknown vaccination history. You wish to prevent tetanus
Commercial bacterin or whole culture bacterin
You have an onwer who wishes to prevent blackleg in his feedlot steers
Commercial modified or avirulent live vaccine
You have horses that you want to vaccinate to prevent Anthrax
Gram positive sporeforming aerobic rod
A description of Bacillus anthracis would be?
Jugular blood sample
The best tissue for bacteriologicalcultureto send to a diagnostic lab from an 800 lb dead steer that you suspect has anthrax would be?
Liver
In clostridium haemolyticum infections in cattle the major site of infection is?
Liver
What is the principal site of infection w/ clostridium piliforme in animals?
Bacteriocidal and time dependent
Imipenem in regards to use in the patient and action on the bacteria is?
Robert Koch
Who identified the causative agent of anthrax?
Intoxication w/o major infection
How would you classify disease caused by clostridium botulinum?
Bacteriostatic and time dependent
Chloramphenicol in regards to use in the patient and action on the bacteria?
Process of translation
Chloramphenicol, in regards to site of action in the bacteria affects?
Demonstrationof bacteria on histopathology
Which of the following would be the most important procedure in the routine confirmation of a diagnosis of Tyzzer’s disease in a foal?
Process of translation
Gentamicin in regards to site of action in the bacteria affects?
Bacteriocidal and concentration dependent
Gentamicin in regards to use in the patient and action on the bacteria is?
Liver
A certain toxin is one major etiologic factor often involved in canine hemorrhagic gastroenteritis. The organ directly affected by the toxin resulting in the symptoms of HGE is?
Gram negative non-sporeforming anaerobic rod
A description of Bacteroides fragilis would be?
Increased permeability
The major mechanism in diarrhea due to Clostridium perfringens Type C infection in a neonatal calf is probably?
Vancomycin
This drug belongs to the glycopeptide family
Tilmicosin
This macrolide drug used to treat cattle and swine is known for having significant toxicity on accidental injection in humans
Amoxicillin
Drug of choice for treatment of clostridial myositis in a horse
Metronidazole
Drug of choice to treat a clostridium difficile infeciton in a horse
Enrofloxacin
Gentamicin
2 antimicrobialswhich are commonly used to treat bacterial infections but which are unlikely to work against anaerobic bacteria
Amoxicillin
Drug of choice for treatment of acute foot rot in dairy cattle
Gentamicin
This drug has long term residues in the kidneys of cattle such that vets recommend that the drug not be used to treat feedlot cattle even tho it can be legally used for treatment
Amoxicillin
Drug of choice for treatment of anthrax in a dog
Chloramphenicol
This drug belongs to the acetamide family of drugs
Amoxicillin
Clavulanic acid is used as a potentiator in combo w/ this drug