Exam III Review Beyond The Individual gene And Genome Chapter 20 Flashcards

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1
Q

The total of all alleles carried in all members of a population

A

Gene pool

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2
Q

Only one allele

A

Monomorphic

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3
Q

More than one allele

A

Polymorphic

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4
Q

Proportion of all total individuals in a population that have particular phenotype

A

Phenotype frequency

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5
Q

Proportion of all total individuals in a population that carry a particular genotype

A

Genotype frequency

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6
Q

Proportion of gene copies in a population that are of a given allele type

A

Allele frequency

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7
Q

One. The population has an infinite number of individuals. Two. Individuals mate at random. Three. No new mutations appear. Four. No migration into or out of the population. Five. Genotypes have no affect on ability to survive and transmit alleles to the next generation.

A

Hardy Weinberg assumptions

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8
Q

A group of interbreeding individuals of a single species living in the same time and place

A

Population

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9
Q

p2 + 2pq + q2 = 1

p + q = 1

A

Hardy Weinberg proportions

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10
Q

Combining DNA indexing system. 13 unlinked highly variable simple sequence repeat loci.

A

Codis

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11
Q

Computer program that uses a random number generator to choose an outcome for each probablistic event, i.e. Mating between individuals in a population. Population size is kept constant. Each run represents a possible pathway of genetic drift

A

Monte Carlo simulation

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12
Q

A change in allele frequency as a consequence of the randomness of inheritance due to sampling error from one generation to the next

A

Genetic drift

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13
Q

Loss of an allele from the population

A

Extinction

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14
Q

Only one allele remains in the population

A

Fixation

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15
Q

A few individuals separate from a larger population and establish a new population that is isolated from the original

A

Founder effects

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16
Q

Large proportion of individuals die often from environmental disturbances or disease

A

Population bottlenecks

17
Q

Variant DNA sequence in and individuals genome that was not present in either parent

A

Mutation

18
Q

Mutation that disrupts important functions

A

Deleterious mutation

19
Q

Mutations that provide a selective advantage

A

Beneficial mutations

20
Q

Mutations without benefit or harm, most mutations

A

Neutral mutations

21
Q

Mutation rates appear to be relatively constant so genetically isolated populations accumulate DNA differences at roughly constant rate. Method to determine how long ago populations diversion from a common ancestor using differences in their DNA

A

Molecular clock

22
Q

An individual’s relative ability to survive (viability) and transmit it’s jeans to the next generation, reproductive success. Cannot be measured within a single individual. Can be measured by considering all individuals of the same genotype.

A

Fitness. W ranges from 1 (all individuals survive to reproduce) to 0 (no individuals survive to reproduce)

23
Q

The process that progressively eliminates individuals whose fitness is lower. individuals whose fitness is higher survive and become the parents of the next generation.

A

Natural selection

24
Q

Recessive lethal alleles do not cause death in the heterozygous form because a certain threshold of protein output is maintained. In the homozygous form, the protein output does not meet the threshold, causing death.

A

Recessive lethal alleles

25
Q

Heterozygotes have the highest fitness

A

Heterozygote advantage

26
Q

Maintains genetic polymorphisms

A

Balancing selection

27
Q

In The absence of the selective agent, resistance is subject to negative selection. mosquitoes

A

Fitness cost

28
Q

DNA maternally derived. One most recent common ancestor

A

Mitochondrial DNA

29
Q

Paternally derived. One most recent common ancestor

A

Y chromosome

30
Q

Modern humans originated in Africa. African populations show much greater DNA sequence diversity then do populations in other parts of the world. non-Africans all share a more recent common ancestor for all genomic regions than do Africans.

A

Out of Africa hypothesis

31
Q

Humanlike hominins. The hominin lineages leaving to Neanderthals and Homo sapiens diversion between 500 and 800,000 years ago

A

Neanderthals

32
Q

A hominin whose lineage separated from the Neanderthal lineage perhaps 600,000 years ago and from the modern human lineage roughly 800,000 years ago. Dennisovians died out roughly 30,000 years ago.

A

Dennisovians

33
Q

FIRMM

A

Fitness, Immigration, random, mutation, migration