Exam 3 Study Guide Flashcards

1
Q

What is the epimysium?

A

surrounds the muscle; “overcoat” of dense irregular connective tissue that surrounds entire muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are fascicles?

A

grouped muscle fibers; resemble bundle of sticks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the perimysium?

A

layer of dense irregular connective tissue that surrounds each layer of the fascicle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is insertion?

A

movable bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is origin?

A

the less movable bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the three basic types of muscle tissue? Which are voluntary and involuntary?

A

skeletal, smooth, and cardiac; skeletal is voluntary, smooth and cardiac are involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do actin and myosin interact?

A

myosin and actin drive skeletal muscle contraction; myosin binds to actin to contract muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why is calcium important?

A

Calcium binds to troponin to change shape and remove tropomyosin; Ca provides the final “go signal” for contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the sarcolemma?

A

plasma membrane of the muscle fiber

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the sliding filament model of muscle contraction.

A

states that during the contraction, the thin filaments slide past the thick ones so that the actin and myosin filaments overlap to a greater degree

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How are muscle fibers stimulated to contract?

A

an action potential travels along the nerve, down the sarcolemma, through its t tubules, and the sarcoplasmic reticulum releases Ca to to bind to troponin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe the events that occur at the neuromuscular junction.

A

-the motor neuron releases ACh that stimulates the skeletal muscle fiber, causing a local depolarization
-muscle fiber excitation; EPP triggers an action potential that travels across sarcolemma
-excitation contraction coupling; AP in sarcolemma propogates along the t tubules and causes release of Ca from terminal cisterns of the SR.
-cross bridge cycling; muscle contracts as a result of a repeating cycle of steps that cause myofilaments to slide relative to each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does ACh do?

A

binds to receptor proteins on the sarcolemma and triggers an action potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does acetylcholinesterase do?

A

breaks down ACh

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the difference between oxidative slow twitch muscle fibers and glycolytic muscle fibers?

A

Oxidative slow twitch muscle fibers are for low intensity long lasting muscle contractions. Glycolytic muscle fibers are best suited for short term rapid intense movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Why are gap junctions important for smooth muscle?

A

gap junctions are communicating junctions between adjacent cells. In smooth muscle, they coordinate changes in both membrane potential and intracellular Ca between adjacent smooth muscle cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What protein binds calcium in smooth muscle?

A

calmodulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the structural divisions of the nervous system?

A

-central nervous system(brain & spinal cord); the control center of the nervous system
-peripheral nervous system(nerves that branch off and extend throughout the body); they carry impulses to and from the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the afferent pathway?

A

information traveling across the afferent pathway approaches the control center

20
Q

Efferent pathway

A

output flows from the control center along the efferent pathway to the third component

21
Q

What are the types of neuroglia in the CNS?

A

-astrocytes
-microglial cells
-ependymal cells
-oligodendrocytes

22
Q

What are the types of neuroglia in the PNS?

A

-satellite cells
-schwann cells

23
Q

Astrocytes

A

most abundant and versatile glial cells; support and brace neurons and anchor them to their nutrient supply lines

24
Q

Microglial cells

A

small and ovoid with relatively long thorny processes; processes touch nearby neurons, monitoring their health and migrate towards neurons that are injured

25
Q

Ependymal Cells

A

many are ciliated; line the central cavities of the brain and spinal cord to form a fairly permeable barrier

26
Q

Oligodendrocytes

A

line up along the thicker nerve fibers in the CNS and wrap their processes tightly around the fibers, producing and insulating covering called myelin sheath

27
Q

Satellite cells

A

surround neuron cell bodies located in the peripheral nervous system

28
Q

Schwann cells

A

surround all nerve fibers in the PNS and form myelin sheath around the thicker nerve fibers

29
Q

What neuroglia makes myelin in the CNS?

A

the oligodendrocytes

30
Q

What neuroglia makes myelin in the PNS?

A

Schwann cells

31
Q

Explain the importance of the myelin sheath

A

the myelin sheath protects and electrically insulates fibers; also increases the transmission speed of nerve impulses

32
Q

How is the myelin sheath formed in the PNS?

A

formed by Schwann cells, which indent to receive an axon and then wrap themselves around it in a jelly roll fashion; form only one segment of a myelin sheath

33
Q

How is the myelin sheath formed in the CNS?

A

Oligodendrocytes form the CNS; they have multiple flat processes that can coil around as many as 60 axons at the same time

34
Q

What is a synapse?

A

a junction that mediates information transfer from one neuron to the next, or from a neuron to an effector cell, it is where the action begins

35
Q

How do neurons communicate with each other?

A

through the neuromuscular junctions(I think)

36
Q

Sensory/afferent neurons

A

transmit info from sensory receptors to CNS; typically unipolar

37
Q

Motor/efferent neurons

A

transmit from CNS to muscle/glands; all multipolar

38
Q

Interneurons

A

sit between and help shuttle signals around; typically multipolar and very common in CNS

39
Q

ATP is required for the myosin head to _____ from actin.

A

release

40
Q

ADP+P is released from the myosin head, resulting in the

A

power stroke

41
Q

What neurotransmitter is used at the neuromuscular junction to send a signal from the motor neuron to the skeletal muscle

A

acetylcholine

42
Q

What occurs during muscle relaxation?

A

ATP binds to the myosin head
the troponin-tropomyosin complex covers the myosin binding sites

43
Q

membrane potential chart

A
  1. resting potential
  2. depolarization
  3. repolarization
  4. hyperpolarization
44
Q

Describe the resting membrane potential

A

-more sodium outside the cell
-more potassium inside the cell
-ACh binding

45
Q

Describe depolarization

A

-sodium goes into the cell
-voltage gated channels open
-action potential

46
Q

Describe repolarization

A

-Na channels close and K channels open
-negative charge restored in cell

47
Q

Describe hyperpolarization

A

-further efflux of potassium
-redistribution of ions and resting potential restored