Exam 3: Lect 3

Question 1

Lymphatic Filarial Worm - Nematode Wuchereria bancrofti

Wuchereria bancrofti:
Adult worm

Answer 1

• Found primarily in lymphatic vessels
• Nuclear column (the cells that constitute the body of the microfilaria), visualized individually, and do NOT extend to the tip of the tail
• Nocturnal periodicity (10pm, to 2am)

Question 2

Lymphatic Filarial Worm - Nematode Wuchereria bancrofti

Wuchereria bancrofti:
Symptom

Answer 2

• After bite from infected moquito - Anopheles or Aedes
• Elephantiasis (blockage of lymph drainage, lymphedema)
• Hydrocele is most common symptom of infection - swelling of scrotum
• Fever, iguinal or axillary lymphadenopathy testicular and or inguinal pain, skin exfoliation, limb ± genital swelling > 6 months to develop then to elephatiasis

Question 3

Lymphatic Filarial Worm - Nematode Brugia malayi

Brugia malayi:
Symptom

Answer 3

• After bite from infected mosquito - Mansonia and Aedes
• Tropical pulmonary eosinophilia
• Cough, wheezing, dyspnea
• Incraesed eosinophils

Question 4

Filarial Worm - Nematode Loa Loa African Eye worm

African Eye Worm:
Symptoms

Answer 4

• Tabanid fly (Deerflies, mando or mangrove flies)
• Episodic angioedema (calabar swellings) Transient swelling marking path of adult microfilaria migration
• Diagnosis - microfilaria from thick or thin blood smears or adults in the subconjuctiva
• Diurnal periodicity (10am to 2pm)

Question 5

Filarial Worm - Nematode Loa Loa African Eye worm

African Eye Worm: Adult worm

Answer 5

• Uninterrupted column of nuclei extend in to the tip of tail