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Exam 3 Drug Facts(Misc. Lectures) Flashcards

1
Q

Mechanism of Bisphosphonates

A

Becomes part of the bone permanently, making bone resistant to resorption

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2
Q

Osteoblasts

A

involved in the buildup of bone
bone forming cell
decreased activity in older age

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3
Q

Osteoclasts

A

involved in bone resorption-removal of calcium of bone into the blood
Always active

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4
Q

Generic of Fosamax

A

alendronate

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5
Q

Dosage form of Fosamax

A

tablet

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6
Q

Dosage form of alendronate

A

tablet

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7
Q

strengths of Fosamax

A

35mg

70mg

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8
Q

strengths of alendronate

A

35mg

70mg

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9
Q

Dosing interval of Fosamax

A

1 weekly

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10
Q

Dosing interval of alendronate

A

1 weekly

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11
Q

How should you take bisphosphonates

A

Take on empty stomach
Take with water
Remain upright for 30 minutes

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12
Q

Generic of Fosamax Plus D

A

alendronate + cholecalciferol

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13
Q

Synonyms for calcium

A

cholecalciferol

ergocalciferol

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14
Q

Dosing interval of Fosamax Plus D

A

1 weekly

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15
Q

Dosage form of Fosamax Plus D

A

tablet

comes in a package of 4

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16
Q

Strengths of Fosamax Plus D

A

70mg alendronate + 70mcg cholecalciferol

70mg alendronate + 140mcg cholecalciferol

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17
Q

What does 70 mcg of cholecalciferol equal?

A

2800 IU Vit. D

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18
Q

What does 140mcg of cholecalciferol equal?

A

5600 IU Vit.D

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19
Q

Dosage form of Rx Vit. D supplement

A

capsule

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20
Q

Strength of Rx Vit. D supplemet

A

50,000 IU

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21
Q

Dosing interval for Rx Vit. D

A

1 weekly

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22
Q

Indication for Rx Vit. D supplemengt

A

used to treat Vit. D deficiency

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23
Q

How much Vit. D is needed to prevent deficiency?

A

400 IU

available OTC

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24
Q

Why is Vit. D needed?

A

Needed to promote absprotion of calcium

Vit. D deficiency leads to increased osteoclast activity =osteopororsis

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25
Q

Generic of Actonel

A

risendronate

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26
Q

Trade of risendronate

A

Actonel

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27
Q

Dosage form of Actonel

A

tablet

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28
Q

Strengths of Actonel

A

35mg

150mg

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29
Q

Dosing interval for Actonel 35 mg

A

1 weekly

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30
Q

Dosing interval for Actonel 150mg

A

1 monthly

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31
Q

Dosing interval for risendronate 35mg

A

1 weekly

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32
Q

Dosing interval for risendronate 150mg

A

1 monthly

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33
Q

Generic of Atelvia

A

risendronate

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34
Q

Dosage form of Atelvia

A

enteric coated delayed release tablet

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35
Q

Dosing interval for Atelvia

A

1 weekly
take after breakfast
empty stomach can lead to GI upset

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36
Q

Generic of Boniva

A

ibandronate

Bisphosphonate

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37
Q

trade of ibandronate

A

Boniva

Bisphosphonate

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38
Q

Dosing interval for Boniva

A

1 monthly

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39
Q

Dosing interval for ibandronate

A

1 monthly

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40
Q

Strength of Boniva

A

150mg

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41
Q

Dosage form of Boniva

A

tablet

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42
Q

Dosage form of ibandronate

A

tablet

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43
Q

Strength of ibandronate

44
Q

Generic of Evista

A

raloxifene

Selective Estrogen Receptor Modulator(SERM)

45
Q

Trade of raloxifene

A

Evista

Selective Estrogen Receptor Modulator(SERM)

46
Q

Indication of Evista

A

for osteoporosis

for breast cancer prophylaxis

47
Q

Indication for raloxifene

A

for osteoporosis

for breast cancer prophylaxis

48
Q

BBW for Evista

A

Can increase risk of deep vein thrombosis (DVT)

May increase risk of stroke

49
Q

Dosing interval of Evista

50
Q

Dosing interval of raloxifene

51
Q

dosage form of raloxifene

52
Q

dosage form of Evista

53
Q

How does SERM work

A

estrogen receptor agonist in bone-decreasing bone resportion

Estrogen receptor antagonist in breast tissue-reduces probability of breast cancer

54
Q

term for blood clot?

55
Q

Definition of thrombus

A

blood clot

56
Q

Generic of Imitrex

A

sumatriptan

Antimigraine agents

57
Q

How do antimigraine agents work?

A

Migraines are caused by vasodilation of the cerebral arteries. Antimigraines cause vasoconstriction

58
Q

Dosage forms of Imitrex

A

tablet
injection
nasal spray

59
Q

Strengths of Imitrex tablet

A

25mg
50mg
100mg

60
Q

Dosing interval for Imitrex tablets

A

1 tablet at onset. Repeat every 2 hours if necessary.Do not exceed maximum daily dose of 200mg

61
Q

What is the max daily dose of Imitrex tablets

62
Q

Strengths of Imitrex Injection

A
  1. 4mg

0. 6mg

63
Q

Dosing interval for Imitrex injection

A

1 inj. at onset. Repeat in 1 hour if needed. Do not exceed 2 injections/day

64
Q

Max dose of Imitrex injection

A

2 inhections per day

65
Q

Strengths of Imitrex nasal spray

66
Q

Dosing interval for Imitex nasal spray

A

1 time use nasal spray bottle
1 spray at onset. Repeat in 2 hours if necessary
Do not exceed 40mg/2 sprays a day

67
Q

Max dose of Imitrex nasal spray

A

2 sprays/40mg per day

68
Q

Generic of Relpax

A

eletriptan

69
Q

Dosage form of Relpax

70
Q

dosage form of eletriptan

71
Q

strength of Relpax

72
Q

strength of eletriptan

73
Q

max daily dose of eletriptan

74
Q

Dosing interval for Relpax

A

1 at onset. Repeat every 2 hours until you reach max dose if necessary

75
Q

Generic of Zomig

A

zolmitriptan

76
Q

trade of zolmitriptan

77
Q

dosage form of Zomig

A

tablet
ODT
nasal spray

78
Q

Strength of Zomig tablet

79
Q

Srength of Zomig-ZMT

80
Q

MAx dose for Zomig tablet

81
Q

Max dose on Zomig-ZMT

82
Q

Dosing interval for Zomig tablet

A

1 at onset. Repeat evry 2 hours until your reach max daily dose

83
Q

Dosing interval for Zomig-ZMT

A

1 at onset. take every 2 hours until you reach max daily dose

84
Q

Whats the trade name of Zomig ODT?

85
Q

Strength of Zomig nasal spray

86
Q

MAx dose of Zomig Nasal spray

87
Q

Dosing interval of Zomig Nasal Spray

A

1 spray at onset. repeat in 2 hours if necessary. Do not exceed 2 sprays/10mg per day

88
Q

Generic of MAxalt

A

rizatriptan

Antimigraine agent

89
Q

Trade of rizatriptan

A

Maxalt

Antimigraine agent

90
Q

Dosage form of Maxalt

91
Q

strength of Maxalt

92
Q

Dosage form of Maxalt-MLT

93
Q

Strength of Maxalt-MLT

94
Q

MAx dose of Maxalt

95
Q

Dosing interval for Maxalt

A

1 at onset. repeat every 2 hours until you reach max daily limit

96
Q

Dosing interval of Lastacaft

97
Q

Dosing interval of alcaftadine

98
Q

Dosing interval of Bepreve

A

twice daily

99
Q

Dosing interval bepotastine

A

twice daily

100
Q

Dosing interval of Optivar

A

twice daily

101
Q

Dosing interval of azelastine

A

twice daily

102
Q

Dosing interval of Zaditor

A

twice daily

103
Q

Dosing interval of ketotifen

A

twice daily

104
Q

Therapeutic class of Pataday

A

Mast Cell Stabalizer

105
Q

Dosing interval of Pataday

106
Q

Dosing interval of olopatadine

107
Q

Mech. of action for Mast Cell Stabalizers

A

decrease histamine production

Drug Info (21 decks)

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