Antiinfective Drug Facts Flashcards
Age limit for fluoroquinolones
18
BBW’s for fluorquionolones
- May cause tendon rupture-especially the Achilles tendon
- Avoid giving to pt’s with myasthenia gravis
Myasnethia gravis
automimmune neuromuscular disease-causes muscle weakness
What other concern is associated with Fluoroquinolones?
lowers the seizure threshold
What shoudl pt’s avoid while taking fluoroquinolones?
multivitamins/dairy of calcium supplement
causes chelation
tablet trade name for moxifloxacin
Avelox
ophthalmic solution trade name for moxifloxacin
Vigamox
Indication for Vigamox
bacterial conjunctivitis
generic for Avelox
moxifloxacin
generic for Vigamox
moxifloxacin
Indication for levofloxacin Op. solution
bacterial conjunctivitis
tablet trade name levofloxacin
Levaquin
generic of Levaquin
levofloxacin
what fluoroquinoloone has the highest incidense
Levaquin (levofloxacin)
trade name of besifloxacin
Besivance
generic for besivance
besifloxacin
dosage form of Besivance
Op. Suspension
dosage form of besifloxacin
Op. suspension
Indication for Besivance
bacterial conjunctivitis
indication for besifloxacin
bacterial conjunctivitis
Trade name for ophthalmic ofloxacin
Ocuflox
generic for Ocuflox
ofloxacin
Dosage form for Oculfox
Op. solution
other dosage form of ofloxacin
otic solutioin
Indication for Ocuflox
bacterial conjunctivitis
generic for Zymaxid
gatifloxacin
trade name for gatifloxacin
Zymaxid
indication for Zymaxid
bacterial conjunctivitis
indication for gatifloxacin
bacterial conjunctivitis
dosage form for gatifloxacin
Op. solution
dosage form for Zymaxid
Op. solution
trade tablet name for ciprofloxacin
Cipro
trade name for Op. soln and ointment for ciprofloxacin
Ciloxan
Inidcation for Ciloxan
bacterial conjunctivitis
auxillary label for Ciprodex
Shake well
ingredients in Ciprodex
ciprofloxacin, dexamethasone
indication for Ciprodex
bacterial conjunctivitis
Ingredients in Tobradex
tobramycin, dexamethasone
what does Tobradex do in children
causes glaucoma
What is Tobradex not indicated fo
bacterial conjunctivitis
generic macrolide
erythromycin
tablet trade name for clarithromycin
Biaxin
strength(s) for Biaxin tablet
250mg, 500mg
strength(s) for clarithromycin tablets
250mg, 500mg
clarithromycin extended release tablet
Biaxin XL
strength(s) of Biaxin XL
500mg
strength(s) of clarithromycin extended release
500mg
strengths for Biaxin granules for oral suspension
125/5 250/5
How do you store Biaxin suspension?
store at room temperature when mixed
trade name for azithromycin
Zithromax
strength(s) for azithromycin tablet
250mg, 500mg
strengths for azithromycin powder for oral suspension
100mg/5ml
200mg/5ml
Who reconstitutes azithromycin powder for oral suspension
reconstituted in the pharmacy
strength of single dose azithromycin powder packet
1 gram
Instructions for pt’s with 1g Azithromycin powder pack
mix with 60ml and drink all at once
INdication for 1g powder pack Azithromycin
chlamydia
dosage form for Z-Max
extended-release microspheres for oral suspension
Strength for Z-Max
2g single dose bottle
Who reconstitutes Z-MAx?
In the pharmacy with 60ml of H20
INstructions for Z-Max to pt’s
Drink within 12 hours
Take on empty stomach
trade name for op. solution of azithromycin
AzaSite
polymer found in AzaSite
DuraSite
Indication for AzaSite
bacterial conjunctivitis
Dosing interval for AzaSite
1 drop twice daily for 2 days, then 1 drop daily for the next 5 days
Storage instructions for AzaSite
store in fridge at pharmacy-pt can store at room temperature
Allergy considerations for Cephalosporins
ceph’s are related to penicillins-pt’s allergic to pennicillins may be allergic to ceph’s
Rule about ceph’s generations
the higher the generations go, the more gram- activity and less gram+ activity
Gen. of Keflex
1st Gen
Gen. of cephalexin
1st Gen
dosage forms of Keflex
capsule
powder for oral suspensions - fridge after reconstitution
trade name for cefadroxil
none
Gen. of cefadroxil
1st Gen
dosage forms for cefadroxil
capsule
powder for oral suspension - fridge after reconstitution
trade name for cefuroxime
Cefdin
Gen. of Cefdin
2nd Gen
generic name for Cefdin
cefuroxime
Gen. of cefuroxime
2nd Gen
Dosage forms of Cefdin
tablet
powder for oral suspension - fridge after reconstitution
trade name for cefixime
Suprax
generic name for Suprax
cefixime
Gen. of Suprax
3rd Gen
gen for cefixime
3rd gen
dosage forms for Suprax
tablet
powder for oral suspension - store at room temp after reconstitution
trade name for cefditoren
Spectracef
generic name for Spectracef
cefditoren
dosage form for Spectracef
tablet - take with food
trade name for cefdinir
none
gen for cefdinir
3rd Gen
dosage form for cefdinir
caspule
powder for oral suspension - store at room temp
Important info about cefdinir
can cause red stool in children
Generic name for Bactroban
mupirocin
trade name for mupirocin
Bactroban
Indication for Bactroban
impetigo-blisters around the mouth
strength of mupirocin
2%
strength for Bactroban
2%
mupirocin trade name for intranasal ointment
Bactroban Nasal
Indication for Bactroban Nasal
eradicate MRSA-methicillin resistant staph aureus
trade name for retapamulin
Altabax
generic name for Altabax
retapamulin
strength of Altabax
1%
strength of retapamulin
1%
dosage form of Altabax
ointment
dosage form for retapamulin
ointment
Indication for Altabax
impetigo
Indication for retapamulin
impetigo
tablet size for Lamisil
250mg
tablet strength for terbinafine
250mg
onychomychosis
fungal infection of the toe or finger nail
tinea unguium
fungal infection of the toe or finger nail
trade name for terbinafine cream
Lamisil AT
strength of Lamisil AT cream
1%
strength of terbinafine cream
1%
Indication(s) for Lamisil
onychomycosis
Indication(s) for Lamisil AT
tinea corporis
tinea pedis
tinea cruris
What is tinea corporis?
Ring worm
What is tinea pedis?
athlete’s foot
what is tinea cruris?
Jock itch
What SALAD drug is often confused with Lamisil?
Lamictal(lamotrigine)
dosage forms of fluconazole
tablet
powder for oral suspension
dosage forms of Diflucan
tablet
powder for oral suspension
Storage for Diflucan suspension
store at room temp
storage for fluconazole suspension
store at room temp
Indications for Diflucan
oral candidiasis
esophageal candidiasis
vaginal candidiasis
Yeast that causes candidiasis
candida albicans
Dose of DIflucan for vaginal candidiasis
150mg single oral dose
dosage forms of Zovirax
capsule tablet ready-to-use oral suspension cream ointment
indications for Zovirax capsule
herpes genitalis
herpes zoster
vericella zoster
herpes labialis
Indications for Zovirax tablet
herpes genitalis
herpes zoster
vericella zoster
herpes labialis
Indications for Zovirax ready-to-use suspension
herpes genitalis
herpes zoster
vericella zoster
herpes labialis
What antiviral is a prodrug?
Valtrex (valacyclovir)
What does Valtrex convert into?
acyclovir
Indication for Zovirax cream
herpes labialis
Indication for Zovirax ointment
genital herpes
Indication for acyclovir cream
herpes labialis
Indication for acyclovir ointment
genital herpes
What is herpes genitalis?
genital herpes
What is herpes zoster?
Shingles
What is varicella zoster?
Chickenpox
What is herpes labialis?
Cold sore
Available strengths for Valtrex
500mg, 1000mg
Available strengths for valacyclovir
500mg, 1000mg
Dosing interval for Valtrex treating initial herpes genitalis
1g twice daily for 10 days
Dosing interval for Valtrex treating recurrent herpes genitalis
500mg twice daily for 3 days
Dosing interval for Valtrex treating herpes zoster
1g three times daily for 1 week
Dosing interval for Valtrex treating herpes labialis
2g in the morning, then 2g in the evening. This is a 1 day dose
Dosing interval for Valtrex treating varicella zoster
Depends on weight - Three times daily for 5 days
What does a neuroaminidase do?
Inhibits the key protein needed for viral replication
Dosage forms for Tamiflu
capsule
powder for oral suspension
Storage info for Tamiflu suspension
store in fridge after reconstitution
INstructions for patients taking Tamiflu
take with food - reduces the nausea associated with taking Tamiflu
Dosing interval for Tamiflu for treatment
Twice daily for 5 days
Dosing interval for Tamiflu for prophylaxis
1 dose daily for 10 days
Dosage forms for Differin
cream
gel
lotion
What causes red stool in children
Cefdinir
Definition of comedo
Initial lesion of acne
Differin reduces comedo formation
Takes 2 to 3 months for a noticable difference