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Exam 3 Flashcards

1
Q

Vector of potyvirus?

A

aphids

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2
Q

NA of potyvirus

A

+ssRNA

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3
Q

What therapeutic agents are used to treat people exposed to influenza?

A

Amantadine and Zanamivir

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4
Q

morphology of the granulovirus

A

has one enveloped nucleocapsid per occlusion body

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5
Q

this virus’s symptoms included hemorrhaged, malaise, abdominal pain, and vommitting

A

filovirus

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6
Q

to which family is influenza a member?

A

orthomyxoviridae

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7
Q

Which gene is unique to plant viruses?

A

cell to cell movement protein gene

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8
Q

What are some ways plant viruses are typically classified?

A

genomic organization, virion morphology, common name of host, and characteristic symptoms

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9
Q

a plant virus with divided genomic molecules that are encapsidated serpatedly

A

a multicomponent plant virus

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10
Q

What are some of the effects of the influenza virus?

A

rhinotracheitis, viral pnemonia, upper repiratory tract infection, followed with bacterial pneumonia

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11
Q

the protein matrix of the baculovirus structure is soluble at which pH?

A

11

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12
Q

The ebola virus genome is

A

-ssRNA

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13
Q

This drig is effective at reduciing the risk of untaxed ppl becoming ill, iused to shorten duration of influenza, can be given to people exposed to influence, and needs to be taken within 48 hrs

A

amantadine

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14
Q

true/falsvirus resistant pants have been generated by genetic engineering through pathogen derived resistance

A

true

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15
Q

which subtypes of influenza virus share antigens?

A

none

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16
Q

what causes the antigenic drift of the influenza virus?

A

cause by point mutations in the RNA genes

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17
Q

Where does maturation of the ebola virus occur?

A

budding of the plasma membrane

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18
Q

Baculoviral envelopes are obtained in the following ways

A

cytoplasmic membranes, de novo asembly, budding through plasma membranes, from peri-nuclear membranes

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19
Q

congenital heart disease, deafness, cataracts, and mental retardation are all symptoms of

A

congenitall rubella syndrome

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20
Q

structural proteins of these viruses ae translated from a 26s subgeneric fragment, rather than from the whole genome

A

alphavirus

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21
Q

Which type of influenza undergoes antigenic shirt

A

A

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22
Q

The marburg virus is transmissible to humans through

A

monkeys

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23
Q

what vector trasmits the tobacco mosaic virus?

A

no know vector

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24
Q

the breaking color of petals, the result of anthocyanin pigment loss

A

variegation

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25
common control methods of plant viruses include
use virus resistant varieties, use of virus free seed or propagation stocks, genetic engineering, control of vectors
26
nucleocapsids are occluded by spheroidic proteins in which subfamily?
chordopoxviridae
27
natural virus transmission includes
seeed, nematode, vegetative, and pollen
28
Which of the following immune system components protects against an infection of the upper respiratory tract with influenza
igA
29
What is a characteristic of the genus granulovius?
one enveloped nucleocapsid per occlusion body
30
what prevents infection of the lungs during an influenza infection?
igG
31
ow does the flavivirus acquire its envelope?
budding into intracellular vesicles
32
what is the primary role of cell mediated immunity in influenza infections?
cell mediated immunity is essential for recovery from both influenza and viral pneumonia
33
baculovirus proteins include
glycoproteins, infected cell proteins, and phosphoproteins
34
what is spheroidin
occlusion protein for entomopoxvirus
35
what restricts an influenza infection to the original site?
heterotypic immunty
36
which type of influenza is associated with pandemics?
influenza a
37
what is the target cell for HIV?
cd4+ t lymphocytes
38
where does the yellow fever get its name?
jaundice
39
what is the genome of the baculoviridae which is pathogenic to insects?
dsDNA
40
where does rubella cause infection, unlike other toavirus infections?
respiratory illness
41
vertical transmission where ovarian follicles are permissive to virus replication
transovarial
42
verticle transmission where virus is transferred to the egg as the egg passes through the oviduct
transovum
43
genome shape for togavirus
linear
44
genome NA for togaviruss
+ssRNA
45
capsid shape for togavirus
icosahedral
46
is togavirus enveloped?
yes
47
what does toga virus's envelop look like
glycoprotein sprides protruding from surface
48
What are the two general of togaviruses
alphaviruse, rubivirus
49
sindis, equine encephalitis, ross river, annoying neon, semliki, and cjikungunya virus are all in the ___ genera
alphavirus
50
vector of alphavirus
mosquitos
51
genome encodes early nonstructural genomes, and then late structural genomes
alphavirus
52
where is alpha virus replication
cytoplasm
53
where do alpha viruses bud
plasma memrane
54
how does alphairus enter into the cell
receptor mediaed endocytosis, faces with endosome
55
what happens after viral DNA of alpha virus binds to ribosome?
2/3 genome transcribed into polyprotein, cleaved into 4 early proteins
56
what acts as the template for more viral genome in alpha virus?
full lengths -RNA (42S) transcribed
57
what codes for late proteins in alpha virus
a smaller 26s RNA transcribe from -RNA template
58
how is alpha virus released from the cell
budding
59
symptoms of alphaviruse
low grade and mild, may be flu-like, may progress to encephalitis
60
amplified by wild birds, 5% of infections result in encephalitis, with 33% mortality and brain damage in most survivors
eastern equine encephalitis virus
61
amplified by rodents, emerging pathogen of humans and quinces in the neotropics
venezuelan equine encephalitis
62
amplified by wild birds, 639 confirmed cases since 1964
western encephalitis virus
63
host: humans, causes fever, rash, polyarthritis, eye pain, chest pain, inflammation of lymph nodes, lethargy, no mortality
onyongnyong
64
hosts: humans, uses fever, joint paints (weeks to months) , rash, headache, muscle pan, nausea, fatigue
chikungunya
65
how is rubella transmitte
airborne droplets
66
this virus causes serious illness in infants and young children, but infection in pregnant women can cause unborn babies to have serious congenital defects or death
rubella
67
symptoms of congenital rubella syndrome
deafness, cataracts, heart defects, mental retardation
68
4 generae in flaviviridae
flavivirus, hepacivirus, pegivirus, pastivirus
69
is flavivirus envelopes?
yes
70
symetry of flavivirus
icosahedreal
71
genome NA of flavivirus
+ssRNA
72
what transmits flaviviridae
mosquitos and ticks
73
flavivirus genome translated into
single polyprotein
74
flavivirus synthesizes __ proteins first
structural
75
how do flavivirus acquire envelope
budding into intracellular vesicles
76
how are flavivirus released
exocytosis or cell lysis
77
yellow fever, dengue, wet nile, are all types of
flavivirus
78
amplified by pigs, incidental hosts, humans and horses,
japaneses encephalitis
79
amplified by birds, incidental hosts humans and horses, causes fever, headache, muscle pain in neck and back
st. louis encephalitis
80
amplified by wild birds, incidental hosts humans, horses,, fever and meningoencephalitis (fatalities mostly in elderly)
west nile
81
rapid onset chilld, headache, dizziness, myalgia then nausea, vomitting, bradycardia, progress to jaundice, renal failure, systemic hemorrhage
yellow fever
82
how long does dengue last
2-7 days
83
malaise, heaache, retroorbital pain, myalgia, arthralgia, can progress to hemorrhagic fever and shock syndrome
dengue
84
infection of one serotype provides ___ term protection against reinfection for dengue
long
85
shape of baculovirus DNA
covalently closed
86
baculovius NA type
dsDNA
87
is baculovirus enveloped?
yes
88
protein matrix of baculovirus, composed of polyhedron protein coded by virus and soluble at alkaline ph
occlusion body
89
when do the early genes get transcribed for baculovirus?
as soon as the DNA is uncoated
90
envelope acquisition of baculovirus
de novo assembly, nuclear and cytoplasmic budding
91
which virus is used for genetic engineering?
baculovirus
92
what is the one mechanism we know of for plant defenses against viruses
post-transcriptional gene silencing
93
plant genes that confer resistance to viruses are known as ____
R genes
94
wgich ig prevents against viral pneumonia
IgG
95
which ig spees recovery from viral infection? for influenza
igg
96
what host defense promotes recovery from influenza and deters spread down the respiratory tract
cell mediated immunity

Virology (12 decks)

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