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Virology > All > Flashcards

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1
Q

How do viruses damage cells?

A

inhibit protein synthesis, toxic viral proteins, competition, etc

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2
Q

How do viruses damage cells?

A

inhibit protein synthesis, toxic viral proteins, competition, etc

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3
Q

How do viruses alter gene expression?

A

apoptosi and cell transformation

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4
Q

induce antiviral atiity and enhance and modify immune response

A

interfereons

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5
Q

what do interferons save

A

neighboring ccells

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6
Q

What are the routes of viral entry?

A

resp, alimentary, skin, genital, conjunctiva

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7
Q

particles ___ micron in mucus membrane of trachea and bronchioles

A

5-10 microns

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8
Q

particles ___ microns inhaled to lungs and affect epithelial cells

A
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9
Q

infect by contactt of mucous membrane

A

large influenza droplets

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10
Q

infect the upper respiratory tract

A

intermediate influenze droplets

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11
Q

infect the lower respiratory tract

A

small influenza droplets

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12
Q

What are the mechanisms of spread in the body?

A

epithelial surfaces, sub epithelial invasion, lymph spread, viremia, invade skin, invade CNS, invade other organs, invade fetus

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13
Q

___ viremia is beofre it gets to other organs

A

1

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14
Q

___ viremia is after it gets to other organs

A

2

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15
Q

___ phagocytose ciruses, passively transferred to cells, or infects them

A

macrophages

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16
Q

pathology of enterovirus

A

enters through oral route, replicates in oropharny, 1 viremia, target, 2 viremia, shed in stool

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17
Q

Where can virus shed from?

A

respiratory and oropharngeal secretions, feces, skin, urine, milk, genitals, blood

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18
Q

cd4

A

helper t

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19
Q

cd8

A

cytotoxic

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20
Q

name the steps of one step growht

A

attachment/adsorption, penetration, eclipse, rise

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21
Q

Which DNA viruses replicate NA in the cytoplasm?

A

Pox and hepadna

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22
Q

Which RNA viruses replicate NA in the cytoplasm?

A

All except Ortho and Retro

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23
Q

Which virus buds from the nuclear envelope

A

Herpes

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24
Q

Which viruses bud from the golgi?

A

Pox, corona, bunya

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25
Q

Which viruses bud from the ER?

A

Hepadna, Flavi

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26
Q

Which virus bud from the plasma membrane?

A

toxa, paramyxo, rhabido, ortho, arena, retro

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27
Q

Viral replication steps

A

Attachment, penetration, uncaring, transcription, replication, assemly, release

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28
Q

How do viruses get in?

A

endocytosis, invaination, viroplexis, interact with cell receptors, and attracted to heparin sulfate

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29
Q

amount of infectious viruses adsorbed per cell

A

MOI

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30
Q

___ ____ helps spill the NA into the cell by helping to unoat

A

M2

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31
Q

what virus uses viral transcriptase

A

pox virus

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32
Q

_____ viruses bud to be released

A

enveloped

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33
Q

_____ viruses lyses

A

naked

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34
Q

types of virus-cell interactions

A

permisive, lytic, productive, abortive, persistant, latent, cytopathic efffects

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35
Q

What are some cytopathic effects

A

plaque formation, enlargement, chance membrane, fusion, vacuoles, inclusion bodies

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36
Q

list DNA viruses

A

Hepadna, Hepres, Adeno, Parvo, Polyoo, Papillo, Pox

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37
Q

list ss + RNA

A

calci pico flavi toga corona retro

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38
Q

What do virsuses in the same order have in common>

A

Same NA and gene order

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39
Q

What do viruses in the same fam have in common?

A

Same NA, gene order and morphology

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40
Q

What do viruses in the same genus have in common

A

same NA, reproductive strategy, differences in genome

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41
Q

Name the 6 orders of viruses

A

Mononega, Nido, Cauda, Picorna, Tymo, Herpes

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42
Q

What are the families in mononega?

A

borna, filo, rhabido, Paramyxo

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43
Q

What are the genesis in Paramyxoco?

A

Parainfluenze, RSV, measles, mumps

44
Q

Which fam is ss - RNA

A

Paramyoxo

45
Q

What families are in Nido?

A

Mesno, Roni, Corona, Arteri

46
Q

What fans are in Cauda?

A

bacteriophages

47
Q

What fams are in Picorna?

A

Cardio, Entero, Hepato, Parnchymo

48
Q

What fans are in Sepses?

A

Alpha, beta, gamm

49
Q

What are some of the smallest viruses?

A

parvo, pappilo, pico, toga

50
Q

What are some of the largest viruses

A

herpes, pox, mini, rhabido, mega

51
Q

Which virus has ds RNA

A

reo

52
Q

Which virus has ambisense RNA

A

bunya

53
Q

Class __ form outside the cell

A

II

54
Q

Class __ form inside the cell

A

I

55
Q

How do viruses alter gene expression?

A

apoptosi and cell transformation

56
Q

induce antiviral atiity and enhance and modify immune response

A

interfereons

57
Q

what do interferons save

A

neighboring ccells

58
Q

What are the routes of viral entry?

A

resp, alimentary, skin, genital, conjunctiva

59
Q

particles ___ micron in mucus membrane of trachea and bronchioles

A

5-10 microns

60
Q

particles ___ microns inhaled to lungs and affect epithelial cells

A
61
Q

infect by contactt of mucous membrane

A

large influenza droplets

62
Q

infect the upper respiratory tract

A

intermediate influenze droplets

63
Q

infect the lower respiratory tract

A

small influenza droplets

64
Q

What are the mechanisms of spread in the body?

A

epithelial surfaces, sub epithelial invasion, lymph spread, viremia, invade skin, invade CNS, invade other organs, invade fetus

65
Q

___ viremia is beofre it gets to other organs

A

1

66
Q

___ viremia is after it gets to other organs

A

2

67
Q

___ phagocytose ciruses, passively transferred to cells, or infects them

A

macrophages

68
Q

pathology of enterovirus

A

enters through oral route, replicates in oropharny, 1 viremia, target, 2 viremia, shed in stool

69
Q

Where can virus shed from?

A

respiratory and oropharngeal secretions, feces, skin, urine, milk, genitals, blood

70
Q

cd4

A

helper t

71
Q

cd8

A

cytotoxic

72
Q

name the steps of one step growht

A

attachment/adsorption, penetration, eclipse, rise

73
Q

Which DNA viruses replicate NA in the cytoplasm?

A

Pox and hepadna

74
Q

Which RNA viruses replicate NA in the cytoplasm?

A

All except Ortho and Retro

75
Q

Which virus buds from the nuclear envelope

A

Herpes

76
Q

Which viruses bud from the golgi?

A

Pox, corona, bunya

77
Q

Which viruses bud from the ER?

A

Hepadna, Flavi

78
Q

Which virus bud from the plasma membrane?

A

toxa, paramyxo, rhabido, ortho, arena, retro

79
Q

Viral replication steps

A

Attachment, penetration, uncaring, transcription, replication, assemly, release

80
Q

How do viruses get in?

A

endocytosis, invaination, viroplexis, interact with cell receptors, and attracted to heparin sulfate

81
Q

amount of infectious viruses adsorbed per cell

A

MOI

82
Q

___ ____ helps spill the NA into the cell by helping to unoat

A

M2

83
Q

what virus uses viral transcriptase

A

pox virus

84
Q

_____ viruses bud to be released

A

enveloped

85
Q

_____ viruses lyses

A

naked

86
Q

types of virus-cell interactions

A

permisive, lytic, productive, abortive, persistant, latent, cytopathic efffects

87
Q

What are some cytopathic effects

A

plaque formation, enlargement, chance membrane, fusion, vacuoles, inclusion bodies

88
Q

list DNA viruses

A

Hepadna, Hepres, Adeno, Parvo, Polyoo, Papillo, Pox

89
Q

list ss + RNA

A

calci pico flavi toga corona retro

90
Q

What do virsuses in the same order have in common>

A

Same NA and gene order

91
Q

What do viruses in the same fam have in common?

A

Same NA, gene order and morphology

92
Q

What do viruses in the same genus have in common

A

same NA, reproductive strategy, differences in genome

93
Q

Name the 6 orders of viruses

A

Mononega, Nido, Cauda, Picorna, Tymo, Herpes

94
Q

What are the families in mononega?

A

borna, filo, rhabido, Paramyxo

95
Q

What are the genesis in Paramyxoco?

A

Parainfluenze, RSV, measles, mumps

96
Q

Which fam is ss - RNA

A

Paramyoxo

97
Q

What families are in Nido?

A

Mesno, Roni, Corona, Arteri

98
Q

What fans are in Cauda?

A

bacteriophages

99
Q

What fams are in Picorna?

A

Cardio, Entero, Hepato, Parnchymo

100
Q

What fans are in Sepses?

A

Alpha, beta, gamm

101
Q

What are some of the smallest viruses?

A

parvo, pappilo, pico, toga

102
Q

What are some of the largest viruses

A

herpes, pox, mini, rhabido, mega

103
Q

Which virus has ds RNA

A

reo

104
Q

Which virus has ambisense RNA

A

bunya

105
Q

Class __ form outside the cell

A

II

106
Q

Class __ form inside the cell

A

I

Virology (12 decks)

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