All Flashcards

1
Q

How do viruses damage cells?

A

inhibit protein synthesis, toxic viral proteins, competition, etc

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2
Q

How do viruses damage cells?

A

inhibit protein synthesis, toxic viral proteins, competition, etc

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3
Q

How do viruses alter gene expression?

A

apoptosi and cell transformation

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4
Q

induce antiviral atiity and enhance and modify immune response

A

interfereons

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5
Q

what do interferons save

A

neighboring ccells

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6
Q

What are the routes of viral entry?

A

resp, alimentary, skin, genital, conjunctiva

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7
Q

particles ___ micron in mucus membrane of trachea and bronchioles

A

5-10 microns

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8
Q

particles ___ microns inhaled to lungs and affect epithelial cells

A
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9
Q

infect by contactt of mucous membrane

A

large influenza droplets

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10
Q

infect the upper respiratory tract

A

intermediate influenze droplets

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11
Q

infect the lower respiratory tract

A

small influenza droplets

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12
Q

What are the mechanisms of spread in the body?

A

epithelial surfaces, sub epithelial invasion, lymph spread, viremia, invade skin, invade CNS, invade other organs, invade fetus

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13
Q

___ viremia is beofre it gets to other organs

A

1

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14
Q

___ viremia is after it gets to other organs

A

2

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15
Q

___ phagocytose ciruses, passively transferred to cells, or infects them

A

macrophages

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16
Q

pathology of enterovirus

A

enters through oral route, replicates in oropharny, 1 viremia, target, 2 viremia, shed in stool

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17
Q

Where can virus shed from?

A

respiratory and oropharngeal secretions, feces, skin, urine, milk, genitals, blood

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18
Q

cd4

A

helper t

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19
Q

cd8

A

cytotoxic

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20
Q

name the steps of one step growht

A

attachment/adsorption, penetration, eclipse, rise

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21
Q

Which DNA viruses replicate NA in the cytoplasm?

A

Pox and hepadna

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22
Q

Which RNA viruses replicate NA in the cytoplasm?

A

All except Ortho and Retro

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23
Q

Which virus buds from the nuclear envelope

A

Herpes

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24
Q

Which viruses bud from the golgi?

A

Pox, corona, bunya

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25
Which viruses bud from the ER?
Hepadna, Flavi
26
Which virus bud from the plasma membrane?
toxa, paramyxo, rhabido, ortho, arena, retro
27
Viral replication steps
Attachment, penetration, uncaring, transcription, replication, assemly, release
28
How do viruses get in?
endocytosis, invaination, viroplexis, interact with cell receptors, and attracted to heparin sulfate
29
amount of infectious viruses adsorbed per cell
MOI
30
___ ____ helps spill the NA into the cell by helping to unoat
M2
31
what virus uses viral transcriptase
pox virus
32
_____ viruses bud to be released
enveloped
33
_____ viruses lyses
naked
34
types of virus-cell interactions
permisive, lytic, productive, abortive, persistant, latent, cytopathic efffects
35
What are some cytopathic effects
plaque formation, enlargement, chance membrane, fusion, vacuoles, inclusion bodies
36
list DNA viruses
Hepadna, Hepres, Adeno, Parvo, Polyoo, Papillo, Pox
37
list ss + RNA
calci pico flavi toga corona retro
38
What do virsuses in the same order have in common>
Same NA and gene order
39
What do viruses in the same fam have in common?
Same NA, gene order and morphology
40
What do viruses in the same genus have in common
same NA, reproductive strategy, differences in genome
41
Name the 6 orders of viruses
Mononega, Nido, Cauda, Picorna, Tymo, Herpes
42
What are the families in mononega?
borna, filo, rhabido, Paramyxo
43
What are the genesis in Paramyxoco?
Parainfluenze, RSV, measles, mumps
44
Which fam is ss - RNA
Paramyoxo
45
What families are in Nido?
Mesno, Roni, Corona, Arteri
46
What fans are in Cauda?
bacteriophages
47
What fams are in Picorna?
Cardio, Entero, Hepato, Parnchymo
48
What fans are in Sepses?
Alpha, beta, gamm
49
What are some of the smallest viruses?
parvo, pappilo, pico, toga
50
What are some of the largest viruses
herpes, pox, mini, rhabido, mega
51
Which virus has ds RNA
reo
52
Which virus has ambisense RNA
bunya
53
Class __ form outside the cell
II
54
Class __ form inside the cell
I
55
How do viruses alter gene expression?
apoptosi and cell transformation
56
induce antiviral atiity and enhance and modify immune response
interfereons
57
what do interferons save
neighboring ccells
58
What are the routes of viral entry?
resp, alimentary, skin, genital, conjunctiva
59
particles ___ micron in mucus membrane of trachea and bronchioles
5-10 microns
60
particles ___ microns inhaled to lungs and affect epithelial cells
61
infect by contactt of mucous membrane
large influenza droplets
62
infect the upper respiratory tract
intermediate influenze droplets
63
infect the lower respiratory tract
small influenza droplets
64
What are the mechanisms of spread in the body?
epithelial surfaces, sub epithelial invasion, lymph spread, viremia, invade skin, invade CNS, invade other organs, invade fetus
65
___ viremia is beofre it gets to other organs
1
66
___ viremia is after it gets to other organs
2
67
___ phagocytose ciruses, passively transferred to cells, or infects them
macrophages
68
pathology of enterovirus
enters through oral route, replicates in oropharny, 1 viremia, target, 2 viremia, shed in stool
69
Where can virus shed from?
respiratory and oropharngeal secretions, feces, skin, urine, milk, genitals, blood
70
cd4
helper t
71
cd8
cytotoxic
72
name the steps of one step growht
attachment/adsorption, penetration, eclipse, rise
73
Which DNA viruses replicate NA in the cytoplasm?
Pox and hepadna
74
Which RNA viruses replicate NA in the cytoplasm?
All except Ortho and Retro
75
Which virus buds from the nuclear envelope
Herpes
76
Which viruses bud from the golgi?
Pox, corona, bunya
77
Which viruses bud from the ER?
Hepadna, Flavi
78
Which virus bud from the plasma membrane?
toxa, paramyxo, rhabido, ortho, arena, retro
79
Viral replication steps
Attachment, penetration, uncaring, transcription, replication, assemly, release
80
How do viruses get in?
endocytosis, invaination, viroplexis, interact with cell receptors, and attracted to heparin sulfate
81
amount of infectious viruses adsorbed per cell
MOI
82
___ ____ helps spill the NA into the cell by helping to unoat
M2
83
what virus uses viral transcriptase
pox virus
84
_____ viruses bud to be released
enveloped
85
_____ viruses lyses
naked
86
types of virus-cell interactions
permisive, lytic, productive, abortive, persistant, latent, cytopathic efffects
87
What are some cytopathic effects
plaque formation, enlargement, chance membrane, fusion, vacuoles, inclusion bodies
88
list DNA viruses
Hepadna, Hepres, Adeno, Parvo, Polyoo, Papillo, Pox
89
list ss + RNA
calci pico flavi toga corona retro
90
What do virsuses in the same order have in common>
Same NA and gene order
91
What do viruses in the same fam have in common?
Same NA, gene order and morphology
92
What do viruses in the same genus have in common
same NA, reproductive strategy, differences in genome
93
Name the 6 orders of viruses
Mononega, Nido, Cauda, Picorna, Tymo, Herpes
94
What are the families in mononega?
borna, filo, rhabido, Paramyxo
95
What are the genesis in Paramyxoco?
Parainfluenze, RSV, measles, mumps
96
Which fam is ss - RNA
Paramyoxo
97
What families are in Nido?
Mesno, Roni, Corona, Arteri
98
What fans are in Cauda?
bacteriophages
99
What fams are in Picorna?
Cardio, Entero, Hepato, Parnchymo
100
What fans are in Sepses?
Alpha, beta, gamm
101
What are some of the smallest viruses?
parvo, pappilo, pico, toga
102
What are some of the largest viruses
herpes, pox, mini, rhabido, mega
103
Which virus has ds RNA
reo
104
Which virus has ambisense RNA
bunya
105
Class __ form outside the cell
II
106
Class __ form inside the cell
I