All Flashcards
How do viruses damage cells?
inhibit protein synthesis, toxic viral proteins, competition, etc
How do viruses damage cells?
inhibit protein synthesis, toxic viral proteins, competition, etc
How do viruses alter gene expression?
apoptosi and cell transformation
induce antiviral atiity and enhance and modify immune response
interfereons
what do interferons save
neighboring ccells
What are the routes of viral entry?
resp, alimentary, skin, genital, conjunctiva
particles ___ micron in mucus membrane of trachea and bronchioles
5-10 microns
particles ___ microns inhaled to lungs and affect epithelial cells
infect by contactt of mucous membrane
large influenza droplets
infect the upper respiratory tract
intermediate influenze droplets
infect the lower respiratory tract
small influenza droplets
What are the mechanisms of spread in the body?
epithelial surfaces, sub epithelial invasion, lymph spread, viremia, invade skin, invade CNS, invade other organs, invade fetus
___ viremia is beofre it gets to other organs
1
___ viremia is after it gets to other organs
2
___ phagocytose ciruses, passively transferred to cells, or infects them
macrophages
pathology of enterovirus
enters through oral route, replicates in oropharny, 1 viremia, target, 2 viremia, shed in stool
Where can virus shed from?
respiratory and oropharngeal secretions, feces, skin, urine, milk, genitals, blood
cd4
helper t
cd8
cytotoxic
name the steps of one step growht
attachment/adsorption, penetration, eclipse, rise
Which DNA viruses replicate NA in the cytoplasm?
Pox and hepadna
Which RNA viruses replicate NA in the cytoplasm?
All except Ortho and Retro
Which virus buds from the nuclear envelope
Herpes
Which viruses bud from the golgi?
Pox, corona, bunya