Exam 2. Viruses Flashcards

Intro to viruses

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1
Q

Virus

A

Associated with evolution of organisms because they can transfer genes
obligate intracellular
Acellular
genetic material surrounded by a protein coat
Not considered because they cant reproduce on their own, they need another cell to reproduce them
Some bacteria are also obligate intracellular, but because they have more of a prokaryote structure are considered living (Chlamydia and Rickettsia)

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2
Q

Nucleic Acid

A

can be either DNA or RNA but not both

double or single stranded

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3
Q

Nucleocapsid

A

Simple virus

capsid and nucleic acid

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4
Q

Capsid

A

Made of capsomeres

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5
Q

Helical

A

Continues helix of capsomeres forming a cylindrical nucleocapsid

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6
Q

Icosahedral

A

3D
20 sided and 13 even corners
Might be most efficient shape

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7
Q

Envelope

A

Protection and attachment
mostly in animals viruses
acquired when virus leaves host cell
spikes outside

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8
Q

Complex virus

A

Bacteriophage

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9
Q

Animal virus multiplication

A
Adsorption
Penetration ( fusion-envelope fuses with membrane or endocytosis- entire virus is engulfed) 
Uncoating
Synthesis
Assembly 
Release
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10
Q

Latent virus

A

Temperate viruses
in cell for long time and cause persistent infection
Lysogenic cycle
not good for therapy

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11
Q

Bacteriophage cycle

A
Adsorption
Penetration
Replication
Assembly and maturation
Lysis and release
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12
Q

Oncovirus

A

Mammalian virus that can cause cancer

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13
Q

Lysogenic cycle

A

Temperate virus
protect the cell from other lytic virus from entering
Results in spread or the virus without killing the host cell
Some pathogens are more virulent because they have prophages

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14
Q

Prophage

A

When virus is retained and copied during normal cell division

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15
Q

in-vitro

A

Cell tissue cultures

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16
Q

In vivo

A

Bird embryos

Live animal inoculation

17
Q

Prions

A
Misfolded proteins
Kuru 
mad cow
No genetic material
Extremely resistant
spongiform encephalopathies
fatal diseases
50 years incubation period
18
Q

Satellite virus

A

Dependent on other viruses

19
Q

Viroid

A

Short pieces of RNA
no protein coat
Only in plants

20
Q

Satellite virus

A

Dependent on other viruses for replication

Adeno-virus: replicates only in cells infected with adenovirus