Exam 1 Flashcards
Antifreeze tx
Alcohol IV
not after 4 hrs or if
after 30 min since ingestion of a corrosive metal
Hydrocarbon solvents ingested
Coma, stupor, delirium or convultions are present
Lavage
Double vision, paralysis
Botox
wrist drop
lead
RBC stippling
lead
anemia and irritable
lead
Keizer… ring around cornea
copper
jaundice
copper
lung cancer
Asbestos
cherry red blood
CO
almond smell
cyanide
SOB
O2 is tx for
cyanide
Do not use lavage
Bleaches
Strong acids
metabolized by CYP450 to free radicals
CCl4 chloroform Carbon tetrachloride
carcinogenic
cirrhosis of liver
Arsenic
CO mechanism
greater affinity for Hb than O2
impares ability of Hb to transport O2
Carboxyhemoglobin is CHERRY RED
isoniazid is example of
PhII before Ph1
Phase 1
Modification of mol thru OXIDATION Rxns
hydroxylation or demethylation (+OH, -CH3)
enzymes attack fx’l groups
can be excreted or to PhII
Phase II
Conjugation: adds Ionized, charged group to PhI to make it more water soluble