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Pharmacology Liza > DOC > Flashcards

DOC Flashcards

0
Q

Neisseria miningitis

A

Pen G (G - cocci)

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1
Q

Neisseria gonorrhoeae (G - cocci)

A

Ceftriaxone or (cefpodoxime ?)

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2
Q

E Coli, Klebsiella, Proteus (G - rod O2)

A

1st or 2nd gen cephalosporin (Cefazolin or Cefaclor) OR

TMP-SMZ (bactrim)

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3
Q

Enterobacter, Citrobacter, Serratia (G- rods O2)

A

TMP-SMZ (bactrim - UTI), quinolone, carbapenem

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4
Q

DOC for UTI

A

1) DOC is bactrium TMP-SMZ
2) Cipro (x pregs/kids)
3) methamine if pregs/kid(UTI drug, not Nitro bc x pregs, 4 mo) OR
(if not pregs/kid: nitrofurantoin?, then if not pregs, why skip Cipro?)

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5
Q

Helicobacter pylori (G- rods O2)

A

BISMUTH+ METROnidazole and tetra or amoxicillin

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6
Q

Vibrio (Cholera)

A

Tetracycline

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7
Q

Pseudomonas Aeruginosa (G- rod O2)

A

AP pen (gr4) + aminoglycoside

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8
Q

Legionella (G- rod O2)

A

Azithromycin (macrolide 50S) + rifampin or

quinolone + rifampin

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9
Q

Strep pneumoniae (G + cocci)

A

Penicillin

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10
Q

Strep pyogenes (G+ cocci)

A

Pen or clindamycin

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11
Q

B-lactamase negative Staph Aureus (G+ cocci)

A

Penicillin

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12
Q

B-lactamase positive Staph Aureus (G+ cocci)

A

Pen resistant penicillin (gr 2)

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13
Q

MRSA

A

Vanco

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14
Q

Enterococcus (G + cocci)

A

Pen +/- amino

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15
Q

Listeria (G + rod)

A

Ampicilline +/- amino

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16
Q

C Diff (- O2)

A

Metronidazole (-02 only!)

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17
Q

Cryptococcus

A

Amphotericin B (no CNS) +/- flucytosine (5FC) (goes to CNS)

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18
Q

Candida

A

Amph B + caspofungin

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19
Q

Aspergillus (fungus)

A

Amph B + Voriconazole

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20
Q

Chlamydia

A

Tetra or macrolide

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21
Q

mycoplasma pneumoniae

A

tetra or erythromycin (macrolide)

22
Q

Mycobacterium Leprae

A

Dapson + rifampin

23
Q

mycobacterium TB

A

isoniazid + rifampin (replace with ______ if renal/liver dysfx or if HIV?) + ethambutol (narrow) + pyrazinamide

24
Q

drugs that treat G+ only

A

Vanco, bacitracin, Daptomycin

25
Q

Drugs that treat G - only

A

Aztreonam, Polymyxin B, (Aminos?)

26
Q

drugs that treat AEROBIC only?

A

Aztreonam, Cipro/quinolones (exc moxi, gemi), AMINOS

27
Q

Drugs that treat anaerobic bacteria only?

A

Metronidazole

28
Q

Clindomycin is DOC for

A 
Strep pyogenes (or pen)
osteomylitis
29
Q

Ampicillin is DOC for

A

Listeria (+/- aminos)

30
Q

Tetracycline is DOC for

A

Vibrio (Cholera)
Mycobacteria Pneumonia (or erythro (macrolide)
Chlamydia (or macrolide: azithro/erythro
H Pylori (Bismuth+Metro and either tetracycline or amoxicillin)
B. burgdorferi (Lyme Dz) (or ceftriaxone)

31
Q

Drugs that should be avoided in pregs and kids

A

1) tetracyclines (<2mo, CNS)

4) Dalfopristin/Quinupristin (kids)

32
Q

Drugs with high drug interaction

A

Dalfopristin/QUinupristin

Erythromycin (highest), azithromycin (lowest)

33
Q

SE of bone marrow depression, gray baby and fatal aplastic anemia

A

CLORamphenicol

34
Q

SE of tendon rupture

A

CIRPO (quinolones)

35
Q

broad and wide spectrum drugs

A 
chloramphenicol
cefepime (4th gen cephalosporin)
3rd gen cephalosporins
Methanamine (broad, esp G-)
Nitrofurantoin (wide)
Cipro (broad or wide)
tetracyclines (and tige(r)cycline)
Telithromycin (ketolide - similar to macrolides)
clindamycin (wide)
Fosfomycin (wide)
Imipenem + meropenem (broad and AP)
Entrapenem (wide - AP)
36
Q

drugs administered orally

A 
Pen V (natural(
Oxacilline (pen resistant Gr2)
Cefixime (3rd gen cephalosporin)
Cipro (quinolone)
Levofloxacin (quinolone)
Bactrim (oral,  parenteral)
Metronidazole (oral, IV, topical)
37
Q

CefOTAXime

A

3rd gen cephalosporin

CNS

38
Q

CeftAZIDime

A

3rd gen cephalosporin

AP, no CNS

39
Q

CefIXime

A

3rd gen cephalosporin

no AP, no CNS but ORAL!

40
Q

CefUROxime

A

2nd gen cephalosporin

41
Q

Does cefepime have AP?

A

Yes

42
Q

CefPROzil

A

2nd gen cephalosporin

43
Q

B.Burgdorgeri (Lyme Dz)

A

doxycycline or amoxicillin or ceftriaxone

44
Q

Mycobacterium Avium

A

Clarithro/Azithro(macrolides) + ethumbutol + rifambutin/refampin/cirpo (quinolones) +/- amikacin (amino)

45
Q

Nocardia (not sure will be asked)

A

TMP-SMX (bactrim) or sulfadiazine

46
Q

Aspergillus

A

Voriconazole + Amph B

47
Q

CAndida

A

CAspofungin + Amph B

GI candida and topical Primarily treated by NYSTATIN!

48
Q

Cryptococcus

A

Amph B (no CNS) +/- Flucytosine (goes to CNS)

49
Q

1) Invasive ASPergillus (in retractive pts) is treated by

2) Non invasive Aspergillus is treated by

A

1) cASPofungin

2) Voriconazole + Amph B

50
Q

Moxarella

A

TMP or Cephalospon gen 2 or 3!! (not gen 1 or 2 which is E. coli, Kleb, Proteus (along with TMP))

51
Q

Mycobacterium Leprae

A

Dapsone + rifampin

do we need to diff multi ( clofazimine-didn’t cover this one?)) or paucibacillary?

52
Q

Lyme Dz

A

doxycycline (tetra - don’t use if pregs/kid) or amoxicillin (pen 3) or ceftriaxone (don’t use if allergy to pens)

Pharmacology Liza (19 decks)

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