Exam 1 Flashcards
Anatomy is
the study of body structures
Gross anatomy
large structures
macroanatomy
visible to the naked eye
microanatomy
requires microscope to observe
Cytology
study of cells
Histology
study of tissues
Regional anatomy
within a region, like thorax
Systemic anatomy
all structures making up a body system- like skeleton
Homeostasis
maintaining steady state
Structural organization of the body
chemical
cellular
tissue
organ
organ system
organism
Metabolism
changes food into energy
anabolism
builds
catabolism
breaks down
Differentiation
cells become specialized/functional
Growth
increase in size
hyperplasia
proliferation, increase cell number
hypertrophy
increase in cell size
deposition
of extracellular material, minerals in bone, connective tissue
Requirements for life
Oxygen
Water
Energy
Micronutrients
Narrow range of temperature
narrow range of atmospheric pressure
Negative feed back loop
reverses change
stimulus- sensor- control- effector
Positive feed back loop
snowball effect
example- birth
Homeohesis
the orchestrated or coordinated control in metabolism of body tissues necessary to support a physiological state
Sagittal plane
divides left vs right sides
Frontal plane
divides the anterior (front) from posterior (rear)
Transverse plane
divides upper vs lower
pleural cavity
surrounds the lungs
pericardium
surrounds the heart
peritoneum
surrounds organs in the abdominal cavity
Serous membranes
serosa
thin membranes that cover organs
Isotopes
each of two or more forms of the same element that contain equal numbers of protons but different numbers of neutrons in their nuclei, and hence differ in relative atomic mass but not in chemical properties
Types of isotopes
radioactive
stable
radioactive isotopes
decay causing radiation=detectable
Stable Isotopes
don’t decay but can be detected by mass spectrometry
used as markers
3 types of reactions
synthesis
decomposition
exchange
Synthesis
make something from ingredients
decomposition
destroy something
exchange
combined decomposition and synthesis
Inorganic
mostly lack carbon; always lack carbon and hydrogen
organic
carbon containing
key inorganics
water
salts
acids and bases
Acids
donate H+ in solution
Bases
donate OH- in solution, or accept H+ in solution
pH
negative base 10 of the H+ ion concentration
buffers
solution of weak acid and its conjugate base
Acidosis
lower than normal pH
Alkalosis
higher than normal pH
Bicarbonate buffering system
carbon dioxide and water added to carbonic acid results in bicarbonate and hydrogen ion
buffer system in the regulation of plasma pH
Key organic compounds
carbs
lipids
proteins
nucleotides
Monomers
single molecule
Oligomers
few molecules
Polymers
many molecules
Carbohydrates functions
energy storage, especially glucose polymers
two types of lipids
saturated
unsaturateds
saturated lipids
linear, higher melting point
unsaturated lipids
kinked chain, more fluid
Functions of proteins
structural
hormonal
buffers
transport electrolytes
bind water
bind carbs
energy source
Lipids nomenclature- delta system
carbons counted from the carboxyl end
#carbons, #double bonds, #carbons from carboxyl end to 1st carbon in the closest double bond
Omega system
carbons counted from the methyl end
Two types of nucleotides
purines
pyrimidines
Nucleoside
sugar and a base
nucleotide
nucleoside and phosphate
Cell membrane components
phospholipid bilayer
cholesterol
embedded proteins
ICF
intracellular fluid
ECF
extracellular fluid
IF
interstitial fluid
Integral proteins
proteins stuck in the membrane
Peripheral proteins
on inside or outside of the cell, may attach to integral proteins
Types of integral proteins
channel proteins
receptors
glycoproteins
The cell membrane is
selectively permeable
Types of transport
passive
-diffusion
-facilitated transport/diffusion
active-requires energy
Osmosis
the transport of water through the membrane
Filtration
a biological/ chemical or physical operation that results in the separation of solid matter from a liquid – by letting the mixture pass through a filter
Hydrostatic pressure
flows form high to lower pressure
In hydrostatic pressure the arterial side is ____ and the venous side is ______
higher pressure
lower pressure
Active transport requires ____ to move materials _____ the concentration gradient
ATP/energy
against
Sodium-potassium pump
Na+/K+ ATPase
pumps 3 Na+ out and 2 K+ in
Secondary active transport
transport of a solute in the direction of its increasing electrochemical potential coupled to the facilitated diffusion of a second solute (usually an ion) in the direction of its decreasing electrochemical potential
Symporters
move 2 molecules in the same direction
antiporters
move 2 molecules in the opposite direction
Endocytosis
a cellular process by which the extracellular materials or cargo are transported into intracellular compartments by a series of pathways followed by the formation of vesicles
Exocytosis
opposite of endocytosis
start in a membrane bound vesicle and secreted out of the cell
Endomembrane system
Endoplasmic reticulum, Golgi apparatus, lysosomes
Organelles for energy production and detoxification
mitochondria
peroxisomes
Cytoskeleton components
microtubules
microfilaments
intermediate filaments
Endoplasmic reticulum
membrane bound channels, continuous with nuclear membrane
Two types rough and smooth
Job of rough ER
covered with ribosomes that participate in protein synthesis
job of smooth ER
lacks ribosomes participates in lipid synthesis
Golgi apparatus
stack of membranes-cisternae
with two sides that sorts, modifies, and sends vesicles to their target site
cis=receives vesicles from ER
trans= releases new vesicles
Lysosomes
large vesicles containing hydrolytic enzymes
Autophagy
self eating
destroy damaged organelles
phago-lysosomes
phagocytized material vesicle fuses with lysosomes= killing chamber
Autolysis
cell self-destruction
digested from the inside out
Mitochondria
organelle with and outer and inner membrane
-highly folded=more surface area
contain DNA
site of cellular respiration