Exam 1 Flashcards
Functions of the kidney?
1) RBC Synthesis
2) H2O and Electrolyte Balance
3) Excrete Metabolic Wastes and Foreign Chemicals
4) Regulate Arterial Blood Pressure via RAAS
5) Regulate RBC and Vit D Production
Functions of the kidney?
1) RBC Synthesis
2) H2O and Electrolyte Balance
3) Excrete Metabolic Wastes and Foreign Chemicals
4) Regulate Arterial Blood Pressure via RAAS
5) Regulate RBC and Vit D Production
The afferent arterioles contain ____ and___ cells
osmoreceptors and granular cells (renin)
The distal tubule contains ___ cells
macula densa (osmoreceptors)
___: Intersection of distal tubule and both the afferent/efferent arterioles
Juxtaglomerular Apparatus (JGA)
Deposition of immune complex in the ____ can trigger immune response lead to sclerosis→loss of glomerular function
Mesangial Cells
Macula Densa have ___ cell type
cuboidal epithelial
Although both cortical and JM Nephrons are located in the cortex of the kidney, ___ dips deeper into the salty medulla and is more important for concentrating urine
JM Nephrons
The ____ contains fenestrations that aid in filtration and is surrounded by podocytes
Glomerulus
Na/K/2Cl- (apical) is located where?
Thick Ascending Limb
What is the role of the Na/K/2Cl-?
Creates salty medulla and establishes ionic gradient that allows water reabsorption in collecting duct
What two cell types are found in the collecting duct?
Intercalated and Principal
Principal Cells reabsorb ____ by secreting __ into lumen
Intercalated Cells reabsorb __ by secreting _ into lumen
Na/H2O; K
K; H
The endothelium, basement membrane, podocytes and Slit Diaphragm all make up the ____