Ex. 5 L1: Preventative Health/Nonhormonal Contraception (43) Flashcards
Menstrual cycle
Two Phases:
Follicular
-Onset of menses through ovulation
Luteal
-Ovulation through onset of next menses
Drop in estrogen -> LH surge -> release of matured follicle (ovulation)
Preventative health: annual exam
Vital signs
Breast exam
Pelvic exam and or screening
Breast exam
Average risk women:
-Self exam or clinical breast exam (varying recommendations)
-Mammogram
Recommended to start by age 40-50
Complete every 1-2 years
Continue until age 75 or when life expectancy is less than 10 years
High risk women:
-I.e. BRCA1 or BRCA2 gene mutations and first-degree relatives
Recommended to receive breast MRI and a mammogram annually starting at age 30
Pelvic exam
Utility
-Screening tool for STIs, gynecologic cancers, pelvic inflammatory disease, ovarian cysts, polyps or fibroids
Components
-Assessments of external genitalia, internal speculum exam or rectovaginal exam
Recommendation
-Not routine in asymptomatic patients
-Performed when indicated by medical hx or symptoms
Cervical screening (PAP) recommendations:
21-29: Pap every 3 years
30-65: Anyone:
-Pap smear every 3 years
-HPV testing every 3 years
-Co-testing (Pap + HPV testing) every 5 years
> 65 years (no prior screenings were normal)
-No screening
Hysterectomy with cervix removal
(no screening)
Additional screening and counseling (PAP)
Cancer
-Endometrial, ovarian, colorectal
Substance use
Domestic violence
Hyperlipidemia
HTN
Diabetes
STIs
Thyroid function
Infertility
Osteoporosis
Obseity
Eating disorders
Sexual dysfunction
Depression
Anxiety
Contraception
Immunizations
HPV
-Most common STI in the US, containing >150 viruses
-14 million new infections every year
-Genital HPV affects 42.5% of adults aged 18-59
-Commonly causes warts (papilloma)
-Genital warts may lead to an increased risk of multiple cancers
HPV transmission
HPV associated cancer cases per year - female
Cervix
11,869
11%
Vagina
875
75%
Vulva
4238
69%
Anus
5150
93%
Oropharynx
3557
63%
HPV associated cancer cases per year - male
Penis:
1,364
63%
Anus:
2,410
89%
Oropharynx
17,248
72%
HPV prevention
Barrier protection (condoms, dental dams)
Mutually monogamous
Male circumcision
HPV screening
HPV vaccination
HPV screening
Patients w/a cervix
-Follow recommended cervical screening guidelines
Patients w/a penis
-Routine screening not currently recommended
Patients at higher risk include men who have sex w/men and or HIV+
May benefit from anal PAP smears
HPV Vaccines
Cervarix (2vHPV)
Serotypes: 16, 18
Admin - no longer available in the US
Gardasil (4vHPV) - no longer available in the US
Gardasil 9 (9vHPV)
Serotypes:
6,11,16,18,31,33,45,52,58
Admin schedule:
Start <15y/o: 2 dose series
-0,6-12 months
Staer >15y/o: 3 dose series
0,2,and 6 months
Females 9-45
Males 9-45
HPV vaccines ages
Ages 19-26:
-Administer 2 or 3 doses series in those who did not start or finish the vaccine series
Ages 27-45:
Vaccination provides less benefit after exposure
Risk vs benefit discussion
HPV vaccine - efficacy
Aged 16-26:
F: 98% cervical cancer
100% vulvar cancer
100% vaginal cancer
M: ~75%
Aged 27-45:
~88-95% effective genital warts, vulvar cancer, vaginal cancer, and cervical cancer in Females
Efficacy in men aged 27-45 is inferred based on this data