Ex. 3 - Asthma Drugs: LAMA

Question 1

LAMA

Answer 1

Long acting antimuscarinics

Question 2

LAMA MOA

Answer 2

Block the bronchoconstrictor effects of AcH on M3 and M2 receptors

Question 3

LAMA drugs

Answer 3

Aclidnium (Turdorza Pressair)
Glycopyrrolate (Seebri Neohaler)
Revenfenacin (Yupelri)
Tiotropium (Spiriva)
Umeclidnium (Incruse Elipta)

Question 4

Aclidnium

Answer 4

LAMA
Brand: Turdorza Pressair
Dosage form: DPI 400 mcg/inhalation

Question 5

Aclidnium dosing

Answer 5

Adult - COPD only

Question 6

Glycopyrrolate

Answer 6

LAMA
Brand: Seebri Neohaler
Dosage form:
15.6mcg capsule
Nebulization solution
25 mcg/mL (1mL)

Question 7

Glycopyrrolate dosing

Answer 7

DPI and Nebulization solution - Adult - COPD only

Question 8

Revefenacin

Answer 8

LAMA
Brand: Yupelri
Nebulization solution
175mcg/inhalation

Question 9

Revefenacin dosing

Answer 9

Adult - COPD only

Question 10

Tiotropium

Answer 10

LAMA
Brand: Spiriva
Dosage form:
HandiHaler: 18mcg/ capsule
Respimat: 1.2 or 2.5 mcg inhalation

Question 11

Tiotropium Dosing

Answer 11

> 6 - yes
Adult - COPD only

Question 12

Umeclidinium

Answer 12

LAMA
Brand: Incruse Ellipta
Dosage: DPI 62.5 mcg/inhalation

Question 13

Umeclidinium dosing

Answer 13

Adult - COPD only

Question 14

LAMA Adverse Effects:

Answer 14

Dry mouth, dizziness, blurred vision, upper respiratory infections, and paradoxical bronchospasms
Totropium *has been approved for use in asthma as an add-on option for children >12yo**