Ex. 4 L1 - MHT 1 (35) Flashcards
When menopause is diagnosed
Confirmed after 12 consecutive months of amenorrhea (absence of menstruation)
Premenopause
The time period of endocrine changes BEFORE cessation of menstruation
Perimenopause (Climacteric)
The period of endocrine changes SURROUND the menopause
Menopause Median age of onset US
51 years (40-58)
Postmenopause
The time period of endocrine changes AFTER cessation of menstruation
Women spend _% of their lives postmenopausal
40%
Premature menopause
AKA “premature Ovarian Insufficiency” (POI)
Occurs before age 40
Hysterectomy, radiation therapy, chemotherapy
1% of women develop premature ovarian failure before 40
Increase risk of mortality and morbidity
Symptom statistics
Worst symptoms occur during first 1-2 years
Symptoms last 7+ years for most women
Causes of menopause
Physiologic
-Extensive deterioration of the follicular cells and ova w/aging
-Decrease estrogen and progesterone levels -> increase FSH and LH level
Surgery
-Removal of ovaries (oophorectomy)
Chemotherapy
-Breast cancer chemotherapy
Radiation therapy
Clinical presentations of menopause: Vasomotor
Hot flashes
Night sweats
(50-87% of symptoms)
Clinical presentations of menopause: Mix
Irregular Menses
Episodic Amenorrhea
Sleep Disturbance
Mood changes (depression, irritability)
Fatigue
(generally lower number due to embarrassment of reporting)
Clinical presentations of menopause: Genitourinary
Vulvovaginal atrophy (vaginal dryness, dyspareunia)
Urinary tract dysfunction
Sexual dysfunction
Urinary frequency, urgency
(27-84%)
Lower incidence of reporting due to embarrassment
Long term consequences of menopause
CV disease
Bone loss
Osteoarthritis
Body composition
Skin changes
Balance
Treatment of Menopausal symptoms: Nonpharmacologic therapies: recommended
Weight loss
Cognitive behavioral therapy
Clinical hypnosis
Stellate ganglion block
Treatment of Menopausal symptoms: Nonpharmacologic therapies: NOT recommended
Lifestyle:
-cooling techniques
-Avoid triggers
-Yoga/exercise
-Dietary modifications
Mind body techniques
-Mindfulness-based interventions
Paced respiration
Dietary supplements
-Soy foods and soy extracts, soy metabolite equol
Supplements/herbal remedies
-cannabis
Others:
Acupuncture, calibration of neural oscillations, chiropractic intervention