EUGLYCEMIC DKA IN DIFFRENT FORMS

Question 1

What is Euglycemic Diabetic Ketoacidosis (DKA)?

Answer 1

Diagnosed with acidosis and ketosis but glucose concentration at $250 mg/dL ($13.9 mol/L)

This condition is characterized by the presence of ketoacidosis without significantly elevated blood glucose levels.

Question 2

What are some causes of Euglycemic DKA?

Answer 2

• Recent insulin administration in type 1 diabetes with inadequate basal insulin
• Decreased caloric intake
• Substantial alcohol consumption
• Chronic liver disease
• Rarely, glycogen storage issues

These factors contribute to the development of euglycemic DKA by affecting metabolic processes.

Question 3

Which medications are known to potentially cause euglycemic DKA?

Answer 3

SGLT-2 Inhibitors

While SGLT-2 inhibitors can lead to euglycemic DKA, this is unlikely in well-controlled type 1 diabetes.

Question 4

What is a likely scenario for a patient experiencing euglycemic DKA?

Answer 4

Patient is most likely rationing insulin

Rationing insulin can lead to inadequate basal insulin levels, triggering euglycemic DKA.

Question 5

How does alcohol intoxication typically affect glucose levels?

Answer 5

Leads to lower glucose levels due to suppressed gluconeogenesis

This metabolic effect can contribute to the development of ketoacidosis.

Question 6

Is adrenal insufficiency likely in cases of euglycemic DKA?

Answer 6

Less likely due to lack of hypotension

The absence of hypotension makes adrenal insufficiency an unlikely cause in this context.