CFRD

Question 1

What is the recommended treatment for cystic fibrosis-related diabetes (CFRD)?

Answer 1

Insulin

Insulin is the best approach due to its beneficial effects on nutrition, pulmonary function, and survival.

Question 2

What are the effects of insulin on patients with CFRD?

Answer 2

Beneficial effects on nutrition, pulmonary function, and survival

Insulin plays a crucial role in managing health outcomes for individuals with CFRD.

Question 3

Are oral hypoglycemic agents effective for enhancing insulin production in CFRD?

Answer 3

Largely ineffective

This includes medications that are typically used for type 2 diabetes.

Question 4

What is the clinical data status on SGLT-2 inhibitors, GLP-1 receptor agonists, or DPP-4 inhibitors for CFRD?

Answer 4

No clinical data available

These classes of medications have not been studied specifically for CFRD.

Question 5

Is metformin expected to be effective for CFRD?

Answer 5

Not expected to be effective

Metformin is commonly used in type 2 diabetes but is not suitable for CFRD.

Question 6

Why is referral to a nutritionist important in the treatment of CFRD?

Answer 6

It supports overall management but insulin therapy is the best approach

Nutritionists can help with dietary adjustments that complement insulin therapy.

Question 7

At what age should screening for CFRD begin?

Answer 7

Age 10

Early screening is crucial for timely diagnosis and management.

Question 8

How often should screening for CFRD be conducted?

Answer 8

Annually

Regular screening helps in early detection and management of CFRD.

Question 9

What method is recommended for screening and diagnosing CFRD?

Answer 9

Two-hour oral glucose tolerance test (OGTT)

This method is standard for diagnosing diabetes, including CFRD.