Esofagul Barrett Flashcards

1
Q

Definitie

A

Aparitia epiteliului columnar pe o lungime de minim 1cm
- metaplazi intestinala cu celule caliciforme pe HP
= leziune premaligna

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2
Q

HP

A
  • 3 tipuri de epiteliu
  • intestinal - risc maxim de malignizare
  • jonctional
  • gastric fundic
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3
Q

Explorari diagnostice

A
  1. EDS
    - 1-3 cm = sd Barrett scurt - minim 4 biopsii
    - > 3cm = segment lung - minim 8 biopsii
    Clasificarea PRAGA
    C = marginea proximala a segmentului circumferential - marginea proximala a pliurilor cardiale
    M = marginea proximala a celui mai lung segment de esofag Barrett - marginea proximala a pliurilor cardiale
  2. Examenul baritat
    - poate identifica ulcer esofagian / stenoza
  3. Ecoendoscopia
    - aprecierea rezecabilitatii endoscopice la un pac cu displazie de grad inalt / ADK
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4
Q

Tratament

A
  1. Medical
    - nu poate induce reversibilitatea metaplaziei; poate ameliora simptomatologia
    IPP 40mg = 12 sapt
  2. Endoscopic = pac cu displazie + ADK st T1a
    - ablatia RFA
    - coagularea in plasma de argon
    - crioterapie
    - electrocoagularea multipolara
    - mucosectomia
  3. Chiururgia
    - tt antireflux
    - esofagectomia - ADK cu invazie submucoasa sau mai profund
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5
Q

Complicatii

A

Ulcerul Barrett - HDS, stenoza, ADK

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6
Q

Supravegherea endoscopica

A

Segment scurt - la 5 ani
Segment lung - la 3 ani
Barrett peste 10cm - trimitere catre centru specializat
la pac >75 ani care nu au fost dg cu displazie pana la acest moment = nu se recomanda supraveghere EDS

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7
Q
A
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