Escape Behaviour Flashcards
When does escape behaviour occur?
Once threat level cross threshold
What are the 2 key processes in escape behaviour?
Integrating information that stimulus is threatening - for threat recognition
Comparing threat against threshold
What is the effect of higher innate aversive stimulus contrast on escape behaviour in mice?
Faster reaction time for escape
Faster movement
What is the effect of low innate aversive stimulus contrast on escape behaviour in mice?
More variation in escape reaction time - low stimulus quality - may not have seen
Which part of the superior colliculus is involved in mouse escape behaviour and why?
Medial part
Represents upper visual field
Threat stimuli from above
What is the role of the dorsal PAG in mouse escape behaviour?
Active defence - e.g. fighting, running away
What is the effect of dorsal PAG inactivation on mouse escape behaviour?
Switches threat response from escape to freezing
What is the effect of medial superior colliculus inactivation on mouse escape behaviour and why?
Abolishes defensive response to threat
Name a calcium sensor
GCaMP6
What does the calcium transient in the mSC represent?
Presence of stimulus
Regardless of escape or not
Stronger with escape response
When does the calcium transient in the mSC occur?
Between threat stimulus and escape response
What does the calcium transient in the dorsal PAG represent?
When animal escapes
When does the calcium transient in the dorsal PAG occur?
Starts at start of escape
Peaks at escape
Describe the escape decision model
Escape once threat intensity threshold reached
Which brain area is activated below the threat intensity threshold for escape?
mSC
