Erysipelothyrx Flashcards
what species is it more prominent in
swine
medically most important
E rhusiopathiae
infects tonsils first
E tonsillarum
gram, shape, respiration, catalase, oxidase, motility, spore, virulence
-gram positive
-long filamentous rod
-facultative anaerobe
-catalase negative
-oxidase negative
-non motile
-non spore forming
-few virulence factors
serotypes of E rhusiopathaie that casue swine erysipelas
1a
1b
2
culture media for growth
-blood agar – alpha hemolytic
-heart infusion supplemented with sodium azide and crystal violet
-nutrient broth and 1% glucose
-triple sugar iron
-requires enriched media
-hydrogen sulfide
smell??
fart smell
habitat
-tonsils
-lymphoid tissue of intestinal tract in carrier animals
-slurry of cattle hers
-sewages from abattoirs
host range
-diverse
transmission
-entry – oral, transmission by flies
-exit – feces, urine, saliva, nasal secretions
virulence factors
only surface structures and enzymes, no toxins
surface structures – capsule
-lipopolysaccharide, slime, glycocalyx
-ressitance to phagocytosis
surface strcutres – surface protective proteins (spA, B, and C antigens)
-biofilm formation
-adhesion
-elicit immune response
-can be used as protective vaccine
enzymes – neuraminidae (sialidase)
-attachment, invasion, destroy blood vessels (hemorrhage and thrombosis)
enzymes – hyaluronidase
-spreading via destroying hyaluronic acid and polysaccharides between adjacent cells
enzymes – superoxide dismutase
-protection from intracellular killing by macropahges
-detoxify free radicals
pigs
diamond skin disease
rhomboid urticarial skin lesions
turkeys
swollen snood
acute turkey erysipelas
humans
erysipeloid
purplish, swollen, hard, painful rash
fish handlers
pig and poultry farmers
abattoir workers
veterinarians
skin problems – dissemination
endocarditis
pneumonia
meningitis
osteomyleitis
arthritis
aboriton
cardiovascular form
-cyanotic extremities
-purplish balck discoloration of abdomen
-septicemia, emboli, infartc, vegetative endocarditis in pigs
joint form
polyarthritis
elbow, hip, hock, stifle, knee
uterine form
-abortion due to fever
-bacteria isolated from fetuses
-can pass placental layers
lacy skin diseasse
-not pus forming bacteria
-diamond shaped skin lesions in pigs
-swollen snood in turkeys
treatment
-penicillin, ampicillin, ceftiofur
control
-vaccinate pigs less than 3m with formalin killed vaccines
-remove sick animals form herd
-good hygiene and biosecurity
-wellbeing and good hygiene
any toxins as virulence factors
no
target body sites
skin
joints
lungs
heart