Equine Sarcoids Flashcards

1
Q

What are equine sarcoids

A

Spontaneous, locally invasive, fibroblastic skin tumors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common tumor in equine?

A

Sarcoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: Equine sarcoids has a high metastatic rate

A

FALSE- no metastasis but recurrence is common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the likely cause of Equine sarcoids?

A

Bovine papilloma virus 1 &2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the three types of sarcoids?

A

Fibroblastic
Verrucous
Occult

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which type of sarcoids appear similar in characteristic to proud flesh?

A

Fibroplastic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which type of sarcoids appear warty like in appearance?

A

Verrucous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which type of sarcoids appear to be slightly raised skin nodules?

A

Occult

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are some pathohistology characteristics of equine sarcoids?

A

Hyperplastic/hyperkeratotic epidermis
Marked rete-peg formation
Irregularly arranged fibroblasts (whorls)
No invasion of underlying muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: DDx of Equine sarcoids include exuberant granulation tissue, fibrosarcoma, cutaneous habronemiasis, squamous cell carcinoma and dermatophytosis

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T/F: Equine sarcoids can spontaneously regress

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are four extreme treatment options for equine sarcoids

A

Sx excision
Cryosurgery
Chemotherapy
Bacillus-Calmette-Guerinimmunotherapy (BCG)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If you use cryotherapy to treat equine sarcoids, how does the site heal?

A

Tissue will slough off and heal by second intention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the chemotherapy drug used to treat equine sarcoids?

A

Cisplatin w/ sesame oil

4 intratumoral injection given Q2wks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where are two common locations for equine sarcoids?

A

Inguinal region or on the head

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does cryosurgery result in tissue destruction?

A

formation of intra- and extracellular ice crystals
Thermal shock before freezing takes place
Cell dehydration
Denaturing lipoprotein complexes in cell membranes

17
Q

T/F: Cryosurgery achieves maximum lethal effects by using a fast freeze, fast thaw method

A

FALSE- fast freeze, slow thaw (at least twice)

18
Q

T/F: Cryosurgery heals by primary intention

A

FALSE- 2nd intention

Forms white hairs around the area
Can take up to 8 weeks to slough
Forms a leathery scar
Give tetanus prophylaxis

19
Q

T/F: BCG therapy has a specific effect on cell mediated immunity

A

FALSE- non-specific effect