Epithelial Tissue Flashcards
covers body surfaces, lines body cavities, and forms glands; characterized by production of keratin intermediate filaments
epithelia
developmental area that gives rise to epidermis, cornea and lens epithelia of eye, enamel organ and enamel of teeth, anterior pituitary, and inner ear
ectoderm
developmental area that gives rise to the neural tube (CNS): pineal body, posterior pituitary, sensory epithelium of eye, ear and nose; and the neural crest (PNS): ganglia, nerves, glial cells, adrenal medulla, melanocytes, neuroendocrine cells
neuroectoderm
developmental area that gives rise to the epithelium of kidneys and gonads, mesothelium lining pleura, peritoneal, and pericardial cavities, endothelium of blood and lymph vessels, and the adrenal cortex
mesoderm
developmental area that gives rise to epithelium of respiratory system, alimentary epithelium excluding the anal and oral cavity, liver, pancreas, gallbladder, thyroid, parathyroid, thymus, tympanic cavity and Eustachian tubes, transitional epithelium of bladder
endoderm
functions as barrier, semi-permeable membrane, secretion, absorption, transport, and sensation
epithelium
epithelium never penetrated by blood vessels
epithelia avascular
_______ is supported by basement membrane, separates epithelium from underlying connective tissue and blood vessels, relies on diffusion of O2 and nutrients from underlying tissue
epithelium
epithelium that lines cavities that connect with outside world (alimentary, respiratory, urogenital); contains surface epithelium of ectoderm, basement membrane, supporting connective tissue (lamina propria), and sometimes layers of smooth muscle
mucous membrane
epithelium that lines closed body cavities (peritoneal, pleural, or pericardial); consists of epithelial lining, mesothelium, basement membrane, and supporting connective tissue; lacks muscularis mucosae
serous membrane
epithelium that lines blood and lymph vessels; associated with variable numbers of muscle and connective tissue layers or tunics
endothelium
T/F Most epithelial cells have finite lifespan
True
extracellular matrix proteins (external lamina) that provides structural support, scaffolding for growth, differentiation, and migration of cells during embryonic growth and regeneration
basement membrane
major components of ________ include GAG’s, type 4 collagen, and structural glycoproteins (laminin, fibronectin, and entactin)
basement membrane
layer of basement membrane in contact with basal cell membrane
lamina lucida
layer of basement membrane that merges with surrounding tissue
lamina reticularis
layer of basement membrane anchored to underlying connective tissue by microfibrils of type 4 collagen
lamina densa
3 functional types of cell junctions
occluding, adhering, and communicating
located immediately beneath luminal surface of simple columnar epithelia that seals intercellular space and prevents leakage
occluding (tight) junctions
continuous, circumferential band formed around the cell where portions of opposing cell membranes fuse together
zonula occludens
present between endothelial cells in wall of blood vessels that promote extravasation of WBCs
fascia occludens
cell junction that binds cells together and act as anchoring points for cell cytoskeleton
adhering (anchoring) junctions
continuous band characterized by transmembrane glycoproteins called cadherins where the adjacent cell membranes are not fused
zonula adherens
small circular patches (spot welds) located on lateral surface of cell that are associated with attachment plaques containing attachment proteins like desmoplakins, desmogleins, and tonofilaments
macula adherens (desmosomes)
most common type of cell junction
macula adherens (desmosomes)
cell junctions found on basal surface of cell only, anchoring it to basement membrane via integrins that are associated with high mechanical abrasion/shearing forces
hemidesmosomes
a specialized, circumferential, intercellular connection that is a hybrid between adhering and occluding junctions that forms diffusion barrier between cells
junctional complex (terminal bar)
zonula occludens (tight junction), zonula adherens (adherens junction), and macula adherens (desmosomes) comprise the ____________
junctional complex (terminal bar)
focal or regional adherent zones located on lateral border of cell that permit passage of small molecules between adjacent cells and allows transport of information and metabolites between cells
gap (nexus) junctions