Epinephrine Flashcards

1
Q

Epinephrine:
Classification -
1. ___

A

Epinephrine
Classification -
1. Beta adrenergic and alpha stimulator.

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2
Q
Epinephrine: 
Action - 
1. \_\_\_ 
     a. \_\_\_ 
     b. \_\_\_ 
     c. \_\_\_ 
     d. \_\_\_ 
     e. \_\_\_ 
     f. \_\_\_
A

Epinephrine
Action -
1. Alpha and beta adrenergic effects.
a. Increases force of myocardial contraction.
b. Increases pulse rate and systolic blood pressure.
c. Increases conduciton velocity through the A-V
node.
d. Increases irritability of ventricles.
e. Dilates bronchi and coronary arteries.
f. Increases cerebral blood flow (alpha effects).

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3
Q
Epinephrine: 
Onset of Action - 
1. \_\_\_ 
2. \_\_\_ 
3. \_\_\_ 
4. \_\_\_ 
5. \_\_\_
A
Epinephrine
Onset of Action - 
1. IV/ET/IO: Immediate. 
2. Push-dose IV: 1 minute. 
3. IM: Variable 
4. Inhalation: 3-5 minutes. 
5. SQ: 6-15 minutes.
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4
Q
Epinephrine: 
Duration of Action - 
1. \_\_\_ 
2. \_\_\_ 
3. \_\_\_ 
4. \_\_\_ 
5. \_\_\_
A
Epinephrine
Duration of Action - 
1. IV/ET/IO: 1-4 hours. 
2. Push-dose IV: 2-5 minutes. 
3. IM: Varies. 
4. Inhalation: 1-3 hours. 
5. SQ: Varies.
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5
Q
Epinephrine: 
Indication - 
1. \_\_\_ 
2. \_\_\_ 
3. \_\_\_ 
4. \_\_\_ 
5. \_\_\_ 
6. \_\_\_ 
7. \_\_\_ 
8. \_\_\_
A
Epinephrine
Indication - 
1. Cardiac arrest: VF, pulseless VT, asystole, PEA. 
2. Anaphylactic shock. 
3. Allergic reactions. 
4. Status asthmaticus. 
5. Bradycardia unresponsive to atropine, TCP, dopamine. 
6. Croup. 
7. Upper airway obstruciton edema. 
8. Hypotension.
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6
Q
Epinephrine: 
Contraindication - 
1. \_\_\_ 
2. \_\_\_ 
3. \_\_\_
A

Epinephrine
Contraindication -
1. Chest pain accompanied by ectopic beats or tachycardia.
2. Do not mix with sodium bicarbonate.
3. Do not use to treat VT secondary to cocaine, or hydrocarbon overdose.

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7
Q

Epinephrine:
Use with Caution -
1. ___
2. ___

A

Epinephrine
Use with Caution -
1. Bronchial asthma and significant emphysema, when patients may also have congestive heart disease.
2. Raising BP and P may cause myocardial ischemia, angina, and increase O2 demand.

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8
Q
Epinephrine: 
Dosage and Administration - 
(1:10,000 = _(concentration)_; 1:1,000 = _(concentration)_) 
1. Adult: 
     a. Cardiac Arrest:
          i. IV/IO: \_\_\_ 
          ii. ET: \_\_\_
A

Epinephrine
Dosage and Administration -
(1:10,000 = 0.1 mg/mL; 1:1,000 = 1 mg/mL)
1. Adult:
a. Cardiac Arrest:
i. IV/IO: 1 mg (10 mL of 1:10,000) every 3-5
minutes; follow with 20 mL NS flush and
elevate arm for 10-20 seconds after dose.
ii. ET: 2-2.5 mg of 1:1,000 mixed with 10 mL NS.

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9
Q
Epinephrine: 
Dosage and Administration - 
1. Adult: 
     b. Profound Bradycardia or Hypotension: 
          i. Push-dose IV: \_\_\_ 
          ii. Infusion IV: \_\_\_
A

Epinephrine:
Dosage and Administration -
1. Adult:
b. Profound Bradycardia or Hypotension:
i. Push-dose IV: Mix 1 mL of 1:10,000 epi with 9
mL NS in a 10 mL syringe (10 mcg/mL) and
administer 0.5-2 mL of push-dose epi eery 2-5
minutes; or
ii. Infusion IV: Infusion IV: Mix 1 mg in 250 mL NS;
administer at 2-10 mcg/minute (om5 mL-2.5
mL), titrating to effect.

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10
Q

Epinephrine:
Dosage and Administration -
1. Adult:
a. Allergic reaction: ___

A

Epinephrine:
Dosage and Administration -
1. Adult:
a. Allergic reaction: 0.3-0.5 mg 1:1,000 IM

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11
Q
Epinephrine: 
Dosage and Administration - 
1. Adult:
     a. Anaphylactic shock:
          i. IM: \_\_\_
          ii. IV/IO: \_\_\_
          iii. ET: \_\_\_
A

Epinephrine:
Dosage and Administration -
1. Adult:
a. Anaphylactic shock:
i. IM: 0.3-0.5 mg 1:1,000
ii. IV/IO: 0.5 mg (5 mL of 1:10,000)
iii. ET: 2-2.5 mg of 1:1,000 mixed with 10 mL NS

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12
Q

Epinephrine:
Dosage and Administration -
1. Adult:
a. Asthma: ___

A
Epinephrine: 
Dosage and Administration - 
1. Adult:
     a. Asthma: 0.3 mg of a 1:1,000 IM; may repeat in 20 
         minutes if necessary.
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13
Q
Epinephrine: 
Dosage and Administration - 
1. Adult:
     a. Upper airway edema due to obstruction:
          i. IM: \_\_\_
          ii. IV: \_\_\_
A
Epinephrine: 
Dosage and Administration - 
1. Adult:
     a. Upper airway edema due to obstruction:
          i. IM: 0.3 mg of a 1:1,000
          ii. IV: 0.3 mg of a 1:10,000
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14
Q
Epinephrine: 
Dosage and Administration -
1. Pediatric:
     a. Croup: _(concentration)_
          i. \_\_\_
          ii. \_\_\_
A

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Croup: 1:1,000
i. 2 mL (undiluted) given blow-by < 6 years old
ii. 3 mL (undiluted) given blow-by >= 6 years old

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15
Q
Epinephrine: 
Dosage and Administration -
1. Pediatric:
     a. Cardiac Arrest/Bradycardia/Anaphylaxis: 
          i. IV/IO: \_\_\_
          ii. ET: \_\_\_
A

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Cardiac arrest/Bradycardia/Anaphylaxis:
i. IV/IO: 0.01 mg/kg of 1:10,000 solution
(0.1 mL = 0.01 mg of 1:10,000 solution, maximum
dose 1 mg)
ii. ET: 0.1 mg/kg (1:1,000 0.1 mL/kg)

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16
Q
Epinephrine: 
Dosage and Administration -
1. Pediatric:
     a. Anaphylactic shock: 
          i. IM:
               a) \_\_\_ for pediatric patients >= 
                   66 lbs
               b) \_\_\_ for pediatric patients < 66 lbs
          ii. IV/IO: \_\_\_
          Iii. ET: \_\_\_
A

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Anaphylactic shock:
i. IM:
a) 1:1,000 0.3-0.5 mg for pediatric patients >=
66 lbs
b) 1:1000 0.15 mg for pediatric patients < 66 lbs
ii. IV/IO: 1:10,000 0.3 mg
iii. ET: use 0.1 mg/kg (1:1,000 0.1 mL/kg)

17
Q

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Allergic reaction/Asthma: ___

A

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Allergic reaction/Asthma: 0.01 mg/kg to maximum
of 0.3 mg IM (0.01 mg = 0.01 mL of 1:1,000)

18
Q
Epinephrine: 
Dosage and Administration -
1. Pediatric:
     a. Upper airway edema due to obstruction:
          i. IM: \_\_\_.
          ii. IV/IO: \_\_\_.
A

Epinephrine:
Dosage and Administration -
1. Pediatric:
a. Upper airway edema due to obstruction:
i. IM: 1:1,000 0.01 mg/kg up to 0.3 mg.
ii. IV/IO: 1:10,000 0.01 mg/kg up to 0.3 mg.

19
Q

Epinephrine
Adverse Reaction -
1. (list of seven)

A

Epinephrine
Adverse Reaction -
1. Myocardial Infarction, Hypertension, Supraventricular tachycardia, Ventricular arrhythmias (Premature ventricular contraction, Ventricular tachycardia, Ventricular fibrillation).