Epilepsy Flashcards

1
Q

Pathology of epilepsy?

A

Abnormal synchronisation of neural activity

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2
Q

Types of epilepsy?

A

Generalised

Partial / focal

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3
Q

When does generalised epilepsy tend to present?

A

Childhood / adolescence

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4
Q

ECG of generalised epilepsy?

A

Spike wave abnormalities

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5
Q

Treatment of generalised epilepsy?

A

Sodium valproate

Lamotrigine if pregnant as sodium valproate is teratogenic

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6
Q

Types of generalised epileptic seizures?

A
Absence
Tonic-clonic
Tonic
Colonic
Atonic
Myoclonic
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7
Q

Abscence seizures

A

Brief <10second pauses

Presents in childhood

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8
Q

Tonic- clinic seizures?

A

Loss of consciousness
Limbs stiffen (tonic) and jerk (clonic)
Post-ictal confusion and drowsiness

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9
Q

Atonic seizure?

A

Sudden loss of muscle tone -> fall

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10
Q

Myoclonic seizure?

A

Sudden jerk of limb, face or trunk

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11
Q

Cause of focal epilepsy?

A

Underlying structural cause

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12
Q

Onset of focal epilepsy?

A

Any age

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13
Q

Types of seizures in focal epilepsy?

A

Simple

Complex

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14
Q

Treatment of of focal epilepsy?

A

Carbamazepine

Lamotrigine

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15
Q

Simple seizures?

A

Awareness is unimpaired

No post-ictal symptoms

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16
Q

Complex seizures?

A

Awareness impaired
Most commonly from the temporal lobe
Post ictal confusion with the temporal lobe
Rapid recovery with frontal lobe

17
Q

What is status epilepticus?

A

seizure >30 mins / repeated seizures without full recovery

18
Q

Treatment for status epilepticus?

A
Lorazepam 
Phenytoin 
Diazepam
Dexamethasone 
General anaesthesia
19
Q

can you take progesterone only pill if taking anticonvulsants?

A

No

20
Q

Affect of anticonvulsants on contraception?

A

Depot progesterone needs more frequent dosing
Progesterone implants not effective
Can alter efficacy of COCP
Morning after pill not adequate if taking AEDs