Brain Tumours Flashcards
Types of glioma?
Astrocytoma
Oligodendroglioma
Ependymoma
What are astrocytomas derived from?
Astrocytes
Who gets astrocytomas?
Children and young adults
What is a low grade glioma?
An astrocytoma - slow growing and truly benign
Treatment for grade 1 glioma?
Surgery is curative
How does a low grade/ grade II glioma/astrocytoma present?
Seizures
Treatment for grade II astrocytoma?
Surgery
+/- radiation / chemo
What is a grade 3 astrocytoma?
Anaplastic astrocytoma - malignant
Survival of a grade 3 astrocytoma?
2 years
What is a grade 4 glioma?
Glioblastoma multiforme - malignant
Survival with grade 4 glioma?
< 1 year
Treatment for malignant gliomas?
Surgery
Post op radiotherapy
Chemo - temozolamide
What are oligodendrogliomas derived from?
Oligodendrocytes
Where are oligodendrogliomas usually found?
Mainly in frontal lobes
Who normally gets oligodendrogliomas?
25-45 year olds
Diagnosis for oligodendrogliomas?
MRI
CT
Biopsy
Treatment of oligodendrogliomas?
Chemo sensitive
Surgery and chemo
Median survival of low grade oligodendrogliomas?
10 years
Who gets meningiomas?
More females
Older
Where do meningiomas starts?
Meninges
Are meningiomas fast growing?
No majority are benign and slow growing
Presentation of meningiomas?
Majority asymptomatic
Headaches
Regional anatomical disturbance
If affect skull base -> cranial nerve neuropathies
Diagnosis of meningiomas?
CT
MRI
Angiography
Treatment of meningiomas?
Small - expectant
Perioperative embolisation
Surgery
Radiotherapy
