Epilepsy Flashcards

1
Q

what is epilepsy

A

abnormal discharge of neurons in the brain

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2
Q

what is epilepsy associated with

A

reduced GABA levels in the brain which leads to abnormal cell-cell message propagation

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3
Q

what are febrile seizures

A

seizures the same as chronic epilepsy but only present in children during fevers

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4
Q

how do you prevent febrile seizures

A

cool down
paracetamol
ibuprofen
remove clothes
cool sponging
cool bath

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5
Q

what are the 2 main classifications of epilpesy

A

generalised and partial

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6
Q

what are the types of generalised epilepsy

A

tonic/clonic, absence, myoclonic/atonic

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7
Q

what are the types of partial stroke

A

simple partial, complex partial, simple sensory

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8
Q

what are epilepsy triggers

A

idiopathic, trauma, CNS disease, social (late nights/flashing lights/alcohol)

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9
Q

what does it mean if the epileptic focus is generalised

A

central focus which spreads signals out to all parts of the cortex so all parts of the body are involved

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10
Q

what does it mean if the epileptic focus is partial

A

the focus is closer to one particular part of the cortex and will primarily affect this part

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11
Q

what does an EEG record

A

electrical activity of brain

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12
Q

what are the stages of the tonic clonic seizure

A

prodromal aura
loss of consciousness
initial tonic (stiff)
clonic (contraction/relaxtion)
post-ictal drowsiness

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13
Q

what is status epilepticus

A

recurrent seizures one after the other

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14
Q

what are petit mal seizures

A

short lived episodes of loss of awareness like vacant stares

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15
Q

what can you do to help someone having a tonic clonic seizure

A

remove objects from mouth and try to prevent injury
use supplemental oxygen

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16
Q

what are the precipitators for seizures

A

withdrawal, epileptogenic drugs (alcohol, SSRIs), fatigue/stress, infection, menstruation

17
Q

what is a jacksonian seizure

A

starts in extremities of upper limb and moves upwards

18
Q

what does a partial seizure affect

A

sensory modality, automatism

19
Q

what is the preventative treatment for epilepsy

A

anticonvulsants (carbamazepine for tonic clonic, levetiracetam for absence)

20
Q

what is emergency care for epilepsy

A

airway and oxygen
benzodiazepines for status epilepticus

21
Q

what is the action of sodium valproate

A

GABA transaminase inhibitor

22
Q

what is the action of benzodiazepines

A

GABA receptor action on CI enhanced

23
Q

what does carbamazepine do to the sodium channel

A

stabilises it

24
Q

what are the dental aspects of epilepsy

A

complications of fits (injuries/fractures)
complications of treatment (hyperplasia, bleeding, folate deficiency)

25
Q

what is the effect of phenytoin on the gingiva

A

gingival hyperplasia

26
Q

what questions do you need to ask an epileptic

A

when last 3 fits
compliance with medication
changes in medication