Epi Curves and Determinants of Disease Flashcards

1
Q

What is a latent period?

A

Microbes are replicating, but not yet enough for the host to be INFECTIOUS.

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2
Q

What is the incubation period?

A

Microbes are replicating, but not yet SYMPTOMATIC. NOTE: Doesn’t always correlate with the latent period.

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3
Q

Define infection.

A

Invasion and multiplication in/on a host.

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4
Q

Define infestation.

A

Invasion, but NOT multiplication in/on a host.

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5
Q

Define contagious.

A

Disease transmissible via direct or airborne routes.

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6
Q

Define communicable.

A

Disease transmissible by direct, airborne or indirect routes.

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7
Q

What do epi curves represent?

A

The number of new cases of disease over time.

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8
Q

What information can an epi curve provide (4 things)?

A

Most probable source of outbreak If pathogen is contagious If outbreak is ending or not Incubation period Outliers

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9
Q

What is the incubation period in this epi curve?

A

3 days

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10
Q

Describe the propagated source pattern.

A

Exposure followed by waves of cases.

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11
Q

What diseases have a propagated source?

A

Contagious diseases

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12
Q

What epi curve pattern is this?

A

Propagated source.

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13
Q

Describe the common source single point exposure pattern.

A

All animals are exposed at once from the same source, has a bell-curve shape.

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14
Q

What diseases show a common source single point exposure pattern?

A

Non-contagious diseases.

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15
Q

What type of incubation time can be determined from a common source single point exposure pattern.

A

The minimum, average and maximum incubation time can be determined.

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16
Q

What epi curve pattern is this?

A

Common source single point exposure

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17
Q

Describe the common source with intermittent exposure curve.

A

No pattern. Animals are exposed at different times.

18
Q

What type of incubation time can you determine from a common source with intermittent exposure curve?

A

Incubation period is not clearly shown.

19
Q

What epi curve pattern is this?

A

Common source with intermittent exposure.

20
Q

What main 3 factors does the epi curve depend on?

A

Host, agent an environment.

21
Q

What factors fall under the “host” umbrella?

A

Host immunity or resistance, direct transmission.

22
Q

What factors fall under the “agent” umbrella?

A

Infectiousness of agent, latent and incubation periods, duration of infectivity.

23
Q

What factors fall under the “environment” umbrella?

A

Fomites, etc.

24
Q

Describe endemic vs. epidemic.

A

Endemic is always present at a steady state in a given population, epidemic is a big spike.

25
Q

What is a determinant of disease?

A

Factors that help determine the probability, distribution or severity in a population.

26
Q

Why are determinants of disease important to know?

A

Helps identify animals at risk, helps prevent disease, helps with differential diagnoses.

27
Q

What is a primary determinant?

A

A MAJOR contributing factor, usually necessary.

28
Q

What is a secondary determinant?

A

Factors that make the disease more or less likely (predisposing or enabling factors).

29
Q

What is an intrinsic determinant?

A

Factors that are internal to the animal (age, breed, sex).

30
Q

What is an extrinsic determinant?

A

Factors that are external to the animal (housing, medical treatment, etc.)

31
Q

T/F: Primary determinants must always be present.

A

True.

32
Q

What are the two agent determinants?

A

Mutations

Resistance

33
Q

What are the 6 environmental determinants?

A

Demographics

Macroclimate

Microclimate

Housing and crowding

Diet

Stress

34
Q

What are the 6 host determinants?

A

Age

Sex and behaviour

Genotype

Breed

Nutrition

Immunity

35
Q

T/F: Genetic diseases are entirely determined by genotype.

A

True

36
Q

T/F: Genetic susceptibilities are entirely determined by genotype.

A

False. Genetic susceptibilities are only partially determined by genotype.

37
Q

T/F: Breeds cannot be used as a visual cue to other, less haritable traits.

A

False. Breed CAN be used as a visual cue.

38
Q

T/F: Diet is intrinsic, Nutrition is extrinsic.

A

False. Diet is extrinsic because it’s a management issue. Nutrition is intrinsic because it directly pertains to the animal.

39
Q

T/F: Immunity is intrinsic, vaccines are extrinsic.

A

True.

40
Q

Define “herd immunity”.

A

Infectious disease can be contained if the population’s resistance to infection is high enough. Doesn’t protect individuals, but many others will be protected indirectly.