Enzymes Flashcards
Oxidoreductase
Alcohol dehydrogenase
Lactate dehydrogenase
Transferase
Hexokinase
Transaminase
Hydrolases
Lipase
Trypsin
Pepsin
(Triacylglycerol ———> 1,2 diacylglycerol + fatty acid)
Lyases
Aldolase
Fumarase
Fructose 16….———-> DHAP
Isomerase
Triose phosphate isomerase
Ligases
Glutamine synthetase
Acetyl CoA carboxylase
Competitive inhibition
Malonate and oxalate are inhibitors of succinic dehydrogenase
Non competitive inhibition
Fluoride inhibits enolase
Cyanide inhibits cytochrome oxidase
Uncompetitive inhibition
Placental alkaline phosphotase inhibited by phenylalanine
Suicide inhibition
Allopurinol is oxidised by xanthine oxidase to alloxanthane
Used to treat gouty arthritis
Feedback inhibition
Heme , ala synthetase
Induction
Insulin induces glucokinase
Repression
Cholesterol synthesis inhibited by inhibiting HMG CoA
Covalent modification
Glycogen synthase
Compartmentation
Fatty acid synthesis — cytosol
B oxidation — mitochondria