Enzymes Flashcards

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1
Q

What is the definition of an enzyme

A

A biological catalyst

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2
Q

What do catalysts do

A

They increase the rate of reaction without being used up

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3
Q

How do enzymes increase the rate of reaction

A

They do this by decreasing the amount of activation energy that is required for a reaction to take place, so more molecules have the activation energy or more allowing them to react.

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4
Q

What is an example of an intracellular enzyme and what does it do

A

Catalase binds to H2O2 also known as hydrogen peroxide and catalyses it’s breakdown into water and oxygen

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5
Q

What is an example of an extracellular enzyme

A

Amylase which is produced in the pancreas and released into the small intestine, catalysing the breakdown of starch into glucose.

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6
Q

What is the molecule that binds to the enzyme called

A

It is called the substrate molecule

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7
Q

What are the molecules that are produced called

A

The products

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8
Q

What is the active site

A

The active site is where the substrate binds to

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9
Q

When the enzyme binds to the substrate what is it called

A

An enzyme substrate complex

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10
Q

What is the substrate in relationship to the active site

A

The active site is complementary to the substrate

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11
Q

What does the complementary nature mean

A

Each enzyme is specific to the substrate ion binds to

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12
Q

What happens once the substrate binds to the active site

A

Amino acids on the active site can form temporary bonds with the substrate ion

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13
Q

What happens to molecules that aren’t complementary

A

It will not be able to bind to the active site

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14
Q

What happens once the reaction is catalysed

A

A product complex is formed and then the product is released from the active site

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15
Q

What are catabolic enzymes

A

enzymes that can break down larger molecules into smaller molecules

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16
Q

What are anabolic enzymes

A

Enzymes that can build up larger molecules from smaller molecules

17
Q

What is the lock and key model

A

The substrate molecule fits perfectly into the active site similar to how a key fits into a lock. Furthermore, only one key can fit into the lock demonstrating the highly specific nature of enzymes.

18
Q

What is the induced fit model

A

The tertiary structure of the active site changes as the substrate approaches. As the substrate starts to form bonds with the active site, the active site undergoes a conformational change so that the active site moulds around the substrate. The conformational change allows the active site to perfectly fit the substrate

19
Q

How does the induced fit model show enzyme specificity

A

Molecules that aren’t the substrate can;t form the correct bonds to the correct amino acids in the active site. So the structure of the enzyme doesn’t adjust to fit the molecule.