Enzyme Inhibtors Flashcards
1
Q
Explain compeptive inhibtors
A
1 active site, 2 substrtaes both substrates fit into the active site so it comperes for the AS substrate 1 is simialr to S2
If the inhibtor goes into the AS it forms a physhical barrier it prevents the eznyme substrate complex
Often reversible
2
Q
What is a non compeptive inhibitor
A
They inhibtor enzyme binds to a diffrent part of the enzyme (allerosteric site)
Binding of the NCI causes a conformational change in the enzyme
This changes shape of the enzyme AS so that it is non complemntary its substarte
Inhibtor binds permantly
3
Q
What is end product inhibtion
A
Enzyme at the begining of the pathway is inhibited by one of the end product of the reaction
