Environmental Influences Flashcards

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1
Q

Pathological environmental influences

A

Environmental factors disturb the course of normal development

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2
Q

Facultative environmental influences

A

The organism has evolved to assimilate environmental influences into its genetic programs
ex: ants

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3
Q

Teratogen

A

An exogenous agent that might interfere with normal development of a fetus
ex: thalomide caused los of long bones in arms

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4
Q

Teratogen sensitive period

A

An exogenous agent that might interfere with the normal development of a fetus

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5
Q

Thalidomide

A
  • Thalidomide binds to Cereblon (CRBN) protein
  • CRBN with mutated Thalidomide binding site
  • When Thalidomide binds to CRVN, SALL4 gets targeted
  • No SALL4 txn factor, no limb feedback loop.
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6
Q

Polyphenism

A

Set environmentally determined phenotypes

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7
Q

Reaction Norm

A

A continuous range of environmentally determined phenotypes

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