Endometriosis and Adenomyosis lecture powerpoint Flashcards
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What age range is endometriosis most often seen
reproductive age because of estrogen dependence
Severity of pain due to endometriosis is not related to…..
….extent of disease
3 types of endometriosis, which is most common?
1) pelvic endometriosis
2) ovarian endometrioma (most common)
3) deep infiltrating endometriosis (could even reach the bowel)
DES exposure is associated with increased….
….endometriosis
Retrograde menstruation theory (pathogenesis of endometriosis)
Endometrial cells shed during menstruation are transported thru fallopian tube ending up in the ovarian area
Coelomic meteaplasia theory (pathogenesis of endometriosis)
Endometrium, ovarian surface, and peritoneum share common embryologic precursor and thus multipotential cells can transform into endometrial cells
Vascular and lymphatic metastasis theory (pathogenesis of endometriosis)
Endometrial cells spread via vascular or lymphatic channels
3 common symptoms of endometriosis
1) dysmenorrhea
2) dyspareunia
3) infertility
1st line diagnosis for endometriosis and gold standard diagnosis
1st line - Transvaginal/transabdominal ultrasound
gold standard - laparoscopy
Gold standard for treatment of endometriosis
Hysterectomy - problem because sometimes women still want kids so ocp and second line agents must be employed instead
2ndary treatment for endometriosis
OCP’s that induce a state of pseudomenopause, includes aromatase inhibitors, progestins, androgen agonists
Pseudomotor cerebri
Benign induced intracranial pressure side effect from treatment of 2ndary endometriosis with ocp’s
Adenomyosis primarily effects..
….parous women over 40 years old
Adenomyosis
growth of glands and stroma within uterine myometrium
Pregnancy is a big risk factor in…
…adenomyosis
